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1.
Cent Eur J Public Health ; 31(1): 57-62, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37086422

RESUMO

OBJECTIVES: The aim of the study was to evaluate the immune status of young people from the Vojvodina province, Serbia, through the detection of IgG antibodies specific for the L1 protein of HPV types 6, 11, 16, and 18 contained in quadrivalent vaccine. METHODS: The study enrolled 514 healthy persons of both genders, aged between 18 and 30 years. All potential participants were informed about the project's aims by trained interviewers before venous blood collection. Also, participants completed a specially designed anonymous questionnaire to identify socio-demographic characteristics and individual behaviours associated with HPV seroprevalence. VPL HPV L1-specific IgG antibodies were measured using a semi-quantitative HPV IgG ELISA kit (Dia.Pro, Italy). RESULTS: A total of 472 (91.8%) young subjects had no detectable antibodies against high- and low-risk HPV types covered by the quadrivalent vaccine. A slightly higher number of seropositive individuals were detected in the age group of 26-30 years compared to younger than 25. Multivariate analysis showed that the number of lifetime sexual partners was the most powerful predictor of HPV seropositivity (OR = 3.483, 95% CI: 1.294-9.379). CONCLUSIONS: Obtained data point out low levels of naturally induced HPV-specific serum antibodies among the target population in the Vojvodina province. The present work highlights the significance and potential benefits of HPV vaccination. Routine HPV vaccination should be the public health priority in our country and should be included in the national immunization programme as soon as possible.


Assuntos
Infecções por Papillomavirus , Vacinas contra Papillomavirus , Humanos , Masculino , Feminino , Adolescente , Adulto , Adulto Jovem , Sérvia/epidemiologia , Papillomavirus Humano , Iugoslávia , Infecções por Papillomavirus/epidemiologia , Infecções por Papillomavirus/prevenção & controle , Estudos Soroepidemiológicos , Anticorpos Antivirais , Imunoglobulina G , Vacinas Combinadas
2.
Acta Vet Hung ; 69(3): 274-281, 2021 09 06.
Artigo em Inglês | MEDLINE | ID: mdl-34506299

RESUMO

In the present study, 64 golden jackals were examined for intestinal helminths in three regions of Vojvodina, Serbia. Among the examined jackals 57.8% were infected with at least one parasite species. Using the intestinal scraping technique (SCT), eight species of intestinal helminths were found: Alaria alata (7.8%), Toxascaris leonina (9.4%), Toxocara canis (4.7%), Uncinaria stenocephala (20.3%), Echinococcus multilocularis (14.1%), Mesocestoides sp. (42.2%), Taenia pisiformis, and Taenia hydatigena (the overall prevalence of Taenia infection was 6.3%). To the best of our knowledge, this is the first report of T. leonina in jackals from Serbia. In comparison with the SCT results, coprological tests were less sensitive and specific for parasite identification, as only two nematode species (T. leonina and T. canis) as well as ancylostomatid and taeniid eggs were identified. The total prevalence of intestinal helminths was higher in males (71.9% males, 45% females), but the difference was not statistically significant (χ 2 = 3.76; P = 0.052). Co-infection with two species of intestinal helminths was found in 35% of the examined golden jackal individuals, three-species co-infection was demonstrated in 21.6%, whereas four-species co-infection was detected in 2.7% of the golden jackals examined. Echinococcus multilocularis has previously been recorded in jackals and foxes in Serbia, but only in Vojvodina. Our results corroborate the findings of previous studies, and indicate that the Vojvodina Province, more specifically the Srem region, is probably a high-risk area for E. multilocularis transmission to humans.


Assuntos
Helmintíase Animal , Helmintos , Animais , Equinococose , Feminino , Raposas , Helmintíase Animal/epidemiologia , Chacais , Masculino , Prevalência , Sérvia/epidemiologia , Iugoslávia
3.
Acta Med Hist Adriat ; 18(2): 291-316, 2021 01 20.
Artigo em Servo-Croata (Latino) | MEDLINE | ID: mdl-33535764

RESUMO

Medical history of the city of Rijeka is a rich treasure trove of events, celebrities and valuable innovations in the field of healthcare. The historical development of Rijeka was largely determined by her geopolitical position as a border town with a multicultural population, marked by strong conflicts of interest and numerous identity turmoil. The great exodus of the domicile population of Italian nationality after World War II has significantly changed the social picture of the city. Among many of such esuli (immigrants) were brothers Giovanni (b. 1932) and Abdon (b. 1933) Pamich, whose lives are reminiscent of the fate of many displaced people from Rijeka who were forced to live in exile after the war. After leaving their hometown during the formative years of their childhood, they had successful careers in Italy in the fields of medicine and healthcare. The older brother Giovanni became a successful surgeon and the younger Abdon a psychologist. Along with his positions as the head of general surgery at the Monfalcone and Gorizia Hospitals, Giovanni Pamich was teaching at the University of Trieste. Abdon Pamich collaborated with the best Italian tennis players in the field of sports psychology, and was a psychologist for the Italian handball team. They both practiced athletics, and Abdon Pamich won the silver medal in speed walking at the 1958 European Championships in Sweden and the gold medal at the 1964 Tokyo Olympics. In addition to emphasizing the achievements of the two brothers in the field of medicine, this paper also addresses the position of the migrant, which is highlighted in Robert Covaz's book "Abdon Pamich, memorie di un marciatore (Rome, 2016), an exciting biography of an emigrant from Rijeka. The paper also explores the concept of thematizing the limits of differences and experiences of migration of Rijeka residents facing the existential issues.


Assuntos
Atletas/história , Emigrantes e Imigrantes/história , Psicologia/história , Cirurgiões/história , Croácia , História do Século XX , História do Século XXI , Itália , Iugoslávia
4.
Environ Sci Pollut Res Int ; 28(13): 16065-16080, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33244701

RESUMO

The investigation conducted in the Vojvodina Province, as a typical European and one of the biggest agricultural regions in the Balkans, offers the research methodology that could be used for any non/flooded agricultural region. The flood impact on heavy elements (HE) content in the flooded arable soil (n = 16) in relation to the control soil (n = 16) was examined, as well as their accumulation in the most often cultivated vegetables (n = 96) in the studied area. Results revealed that the flood did not significantly change the pseudo total HEs concentration in the soil as well as their amounts accumulated in different soil fractions. In both soils, only the average content of Ni exceeded the maximum permissible values set by Serbian soil quality standard which is in line with the Dutch standard. In comparison with the background values, notable enrichment is found for most of analyzed elements in both soils. Soil pollution status was assessed through several indices indicating that contamination range was in the domain from a moderate to a highly polluted. The principal component analysis demonstrated that soil contamination was probably originated from agricultural/anthropogenic activities (Cd, Cu, As, Pb), apart from Ni, Cr, and Co which came from natural weathering of the parent material. Carcinogenic and non-carcinogenic risks of selected HEs for Serbian population in the investigated region were below the threshold values. The average levels of Pb in investigated potato and carrot samples were higher than the maximum allowable concentrations established by EU/Serbian regulation. The total hazard quotients (THQ) of HEs through intake of analyzed vegetables were below the safe threshold (˂ 1), suggesting the absence of adverse health effects.


Assuntos
Metais Pesados , Poluentes do Solo , Península Balcânica , China , Monitoramento Ambiental , Poluição Ambiental/análise , Inundações , Metais Pesados/análise , Medição de Risco , Sérvia , Solo , Poluentes do Solo/análise , Verduras , Iugoslávia
5.
J BUON ; 25(2): 655-661, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32521849

RESUMO

PURPOSE: Breast cancer is the most common type of malignant tumor in women and one of the most significant public health problems in the world. The purpose of this work was to determine breast cancer epidemiology in the Autonomous Province of Vojvodina in a 20-year period (1993 to 2012) by determining breast cancer incidence and mortality in female population and analyzing the trend in the specified period. METHODS: The research involved the population of women in Vojvodina in the period from 1993 to 2012. Data were obtained from the Register for malignant neoplasms of Vojvodina. Incidence and mortality trends were analyzed by a joinpoint regression analysis. RESULTS: A total of 20,242 cases of breast cancer were registered in the observed period. Standardized incidence ratio in 2012 was 71.2/100,000. The trend of incidence increased with an average annual percentage of growth of 2.10. A total 10,062 deaths due to breast cancer were documented. Standardized incidence ratio in 2012 was 28.6/100,000. An increase of mortality rate by 1.70% per year was recorded in the period from 1992 to 2006 and a decline in the mortality rate by 1.56% was noticed afterwards. The highest percentage of deaths due to breast cancer was recorded in a group aged 60-69 years (26.7%).


Assuntos
Neoplasias da Mama/mortalidade , Feminino , Humanos , Incidência , Mortalidade , Iugoslávia/epidemiologia
6.
PLoS One ; 15(1): e0227679, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31940403

RESUMO

Motivated by the One Health paradigm, we found the expected changes in temperature and UV radiation (UVR) to be a common trigger for enhancing the risk that viruses, vectors, and diseases pose to human and animal health. We compared data from the mosquito field collections and medical studies with regional climate model projections to examine the impact of climate change on the spreading of one malaria vector, the circulation of West Nile virus (WNV), and the incidence of melanoma. We analysed data obtained from ten selected years of standardised mosquito vector sampling with 219 unique location-year combinations, and 10 years of melanoma incidence. Trends in the observed data were compared to the climatic variables obtained by the coupled regional Eta Belgrade University and Princeton Ocean Model for the period 1961-2015 using the A1B scenario, and the expected changes up to 2030 were presented. Spreading and relative abundance of Anopheles hyrcanus was positively correlated with the trend of the mean annual temperature. We anticipated a nearly twofold increase in the number of invaded sites up to 2030. The frequency of WNV detections in Culex pipiens was significantly correlated to overwintering temperature averages and seasonal relative humidity at the sampling sites. Regression model projects a twofold increase in the incidence of WNV positive Cx. pipiens for a rise of 0.5°C in overwintering TOctober-April temperatures. The projected increase of 56% in the number of days with Tmax ≥ 30°C (Hot Days-HD) and UVR doses (up to 1.2%) corresponds to an increasing trend in melanoma incidence. Simulations of the Pannonian countries climate anticipate warmer and drier conditions with possible dominance of temperature and number of HD over other ecological factors. These signal the importance of monitoring the changes to the preparedness of mitigating the risk of vector-borne diseases and melanoma.


Assuntos
Mudança Climática , Malária/epidemiologia , Melanoma/epidemiologia , Febre do Nilo Ocidental/epidemiologia , Animais , Anopheles/metabolismo , Anopheles/patogenicidade , Culex/virologia , Humanos , Incidência , Insetos Vetores/virologia , Mosquitos Vetores/virologia , Estações do Ano , Sérvia/epidemiologia , Temperatura , Vírus do Nilo Ocidental , Iugoslávia/epidemiologia
7.
Eur J Cancer Care (Engl) ; 27(2): e12825, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29345023

RESUMO

This study aimed at exploring how women from Iraq and the former Yugoslavia, diagnosed with breast cancer and living in Sweden, experience their everyday life during radiation therapy. A qualitative research design was used comprising interviews with ten women, five originating from Iraq and five from the former Yugoslavia. Striving to survive, the women experienced their everyday life during radiation therapy as extremely challenging. This experience can be placed into three categories: strategies for survival, keeping up appearances and staying in control. Because of these specific challenges, immigrant women may need additional information and guidance in conjunction with the diagnosis, which may enable them to identify possible sources of support from those closest to them. Also, greater attention should focus on acknowledging the woman behind the diagnosis, regardless of her origin, to develop an individualised support programme to help her cope with everyday life during radiation therapy.


Assuntos
Neoplasias da Mama/psicologia , Sobreviventes de Câncer/psicologia , Acontecimentos que Mudam a Vida , Adaptação Psicológica , Adulto , Idoso , Atitude Frente a Saúde , Neoplasias da Mama/etnologia , Neoplasias da Mama/radioterapia , Relações Familiares , Feminino , Humanos , Iraque/etnologia , Pessoa de Meia-Idade , Suécia/epidemiologia , Revelação da Verdade , Iugoslávia/etnologia
8.
Hist. ciênc. saúde-Manguinhos ; 24(supl.1): 91-103, 2017. tab
Artigo em Inglês | LILACS | ID: biblio-892575

RESUMO

Abstract The paper shortly presents the early roles of Budapest, Prague, and Belgrade in the development of psychoanalytic movement in Central-Europe before the Second World War. Mapping this historical heritage, it suggests how psychoanalysts of former Soviet Bloc countries could restore their own psychoanalytic communities. The study investigates the consequences of these dictatorial and authoritarian regimes for psychoanalysis and for psychoanalysts focusing on similarities and differences in Hungary, in former Czechoslovakia, and Yugoslavia. Furthermore, it emphasizes the contribution of the international professional organizations - the International Psychoanalytic Association, and the European Psychoanalytic Federation - for reintegration of Budapest, Prague, and Belgrade to the international psychoanalytic community.


Resumo O artigo apresenta brevemente os papéis de Budapeste, Praga e Belgrado no desenvolvimento do movimento psicoanalítico na Europa central antes da Segunda Guerra Mundial. Mapeando essa herança histórica, o artigo sugere como psicanalistas do antigo bloco soviético puderam restaurar suas próprias comunidades psicoanalíticas. O estudo investiga as consequências desses regimes ditatoriais e autoritários para a psicanálise e para os psicanalistas focalizando as semelhanças e diferenças na Hungria e nas antigas Tchecoslováquia e Iugoslávia. Além disso, destaca a contribuição das organizações profissionais internacionais - a International Psychoanalytic Association e a European Psychoanalytic Federation - na reintegração de Budapeste, Praga e Belgrado à comunidade psicoanalítica internacional.


Assuntos
Humanos , História do Século XX , Psicanálise/história , Iugoslávia , Tchecoslováquia , História do Século XX , II Guerra Mundial , Hungria
9.
Turk J Med Sci ; 46(1): 97-104, 2016 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-27511341

RESUMO

BACKGROUND/AIM: The aim of this study was to determine the presence and age distribution of different oncogenic human papilloma virus (HPV) types in women in the South Backa region and its relationship to Pap results. MATERIALS AND METHODS: In a group of 1087 women with normal and abnormal cytology, the commercial HR HPV Real-TM kit (Sacace Biotechnologies, Italy) was used. RESULTS: Overall, 50.5% of the women were HPV positive. The presence of HPV types 18, 31, 51, and 58 was significantly influenced by age, while the presence of HPV types 16 and 45 was significantly influenced by cervical cytology. Results of the LSD test show a wide spectrum of high risk HPV among women with normal cytology and women with a low grade cervical lesion rate (atypical squamous cell of undetermined significance (ASCUS) and low grade squamous intraepithelial lesions (LSIL). The most prevalent HPV types found were 16, 31, 51, 18, and 52. In the HSIL group the most prevalent HPV types were 16 and 45. CONCLUSION: The reported results provide new data on the circulation of oncogenic HPV genotypes and frequency of multiple infections among women in Vojvodina and suggest that a prophylactic vaccine against HPV 16 and 18 has the potential to prevent approximately half of the high-grade lesions.


Assuntos
Papillomaviridae , Feminino , Humanos , Infecções por Papillomavirus , Sérvia , Neoplasias do Colo do Útero , Iugoslávia , Displasia do Colo do Útero
10.
Med Pregl ; 68(7-8): 277-82, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26591642

RESUMO

As a peacetime work of Katherine S. Macphail (Glasgow, 1887- St.Andrews, 1974) MB ChB (Bachelor of Medicine and Surgery), the Anglo-Serbian Children's Hospital in Belgrade was established after World War I, and the English-Yugoslav Children's Hospital for Treatment of Osteoarticular Tuberculosis was founded in Sremska Kamenica in 1934. Situated on the Fruska Gora slope, the hospital-sanatorium was a well-equipped medical institution with an operating theatre and x-ray machine providing very advanced therapy, comparable to those in Switzerland and England: aero and heliotherapy, good quality nourishment, etc. In addition, school lessons were organized as well as several types of handwork as the work-therapy. It was a privately owned hospital but almost all the children were treated free of cost. The age for admission was up to 14. During the period from 1934 to 1937, around 458 children underwent hospital treatment, most of them with successful results. During the war years the Sanatorium was closed but after the war it was reactivated. In 1948 by the act of final nationalization of all medical institutions in the communist Yugoslavia, the hospital was transformed into a ward of orthopedic surgery under the supervision of the referent departments in Belgrade and Novi Sad. Today, hospital is out of work and deprived of its humanitarian mission. The building is neglected and in ruins although it has been proclaimed the national treasure by the Regional Institute for Protection of Monuments of Culture.


Assuntos
Hospitais de Doenças Crônicas/história , Hospitais Pediátricos/história , Médicas/história , Tuberculose Osteoarticular , I Guerra Mundial , História do Século XX , Sérvia , Iugoslávia
11.
13.
Vojnosanit Pregl ; 71(3): 239-44, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24697009

RESUMO

BACKGROUND/AIM: In a combat environment the extremities continue to be the most common sites of injury with associated high rates of infectious complications due to initial contamination. The aim of this observational study was to determine therapeutic procedures effective in a combat environment and to assess functional outcomes of definitive Scare. METHODS. A total of 44 casualties with combat-related lower extremities fractures sustained during combat operations in former Yugoslavia in a 2-year period (1993-1994) were enrolled. Initial management of these injuries was performed at battlefield (echelon 1), surgical treatment was provided in the hospital in Trebinje (echelon II) and definitive care was provided in the Orthopedic Ward of General Hospital in Nikiid (echelon III). RESULTS. All combat casualties received surgical treatment within 6-48 hours. Antibiotics were administered during hospitalization in 37 (84%) of all the patients. In all the cases fractures healed, while 15 (38.59%) of them developed complications (most notably osteomyelitis in 3 of the cases, dysfunction in adjacent joints in 3 of the cases and infection of the soft tissue around pins in 3 of the cases). Follow-up period was a little bit over 2 years and reliable conclusions regarding the therapy and the outcomes could be made. Good functional outcomes were prevalent (63.63%), satisfactory were present in one fifth and inadequate in 13.63% of all the cases. There were no amputations or fatalities. Internal fixation was shown to be the method of definitive surgical care of combat-related lower extremity fractures. CONCLUSION. The management of combat-related lower extremity fractures is complex, multidisciplinary approach through echelons is necessary and internal fixation as the method of definitive surgical care is essential.


Assuntos
Antibacterianos/uso terapêutico , Traumatismos da Perna/cirurgia , Militares , Procedimentos Ortopédicos/métodos , Infecção dos Ferimentos/tratamento farmacológico , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Centros Cirúrgicos , Guerra , Adulto Jovem , Iugoslávia
14.
Med Glas (Zenica) ; 11(1): 132-7, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24496354

RESUMO

AIM: To evaluate clinical status of patients with chronic subdural hematoma (CSDH) on hospital admission and to predict their outcome after the neurosurgery treatment using Karnofsky index scale (KI). METHODS: Clinical and surgery data of patients with CSDH were collected prospectively. Fifty 50 adults aged over 41 with CSDH diagnosed and hospitalized between November 2010 and April 2012 were investigated. In the analyzed sample there were more CSDHs in males than in females (1.5:1). The diagnosis of CSDH on hospital admission in patients was confirmed by non-contrast computed tomography (CT). Forty-three patients had undergone surgery with Burr-hole drainage and craniotomy, while seven patients were treated conservatively. The KI was used for evaluation of the patient's clinical state before neurosurgery treatment and the quality of survival in all patients, six months after hospital discharge. RESULTS: A statistically significant difference was found between the KI values in patients with CSDHs on hospital admission and KI after the surgical treatment. Six months after, out of 43 patients who underwent surgery in 24 (55.8%) patients KI was between 80-100%, in nine (20.9%) patients KI was between 50-70% and in 10 (23.2%) patients KI was 0-40%. CONCLUSION: Although the elderly with CSDHs are vulnerable because of their age, associated diseases and risk of recurrence of CSDH, their outcome assessed by KI after surgical treatment was good. The Glasgow Coma Scale (GCS) is used for rapid assessment of the state of consciousness in patients on admission and monitoring of the changes in their condition. KI scale could be used as a complementary assessment tool for the general condition of patients with chronic subdural hematoma. This study highlighted that the KI scale had a predictive value for patient's outcome with chronic subdural hematoma.


Assuntos
Hematoma Subdural Crônico/diagnóstico , Hematoma Subdural Crônico/cirurgia , Avaliação de Estado de Karnofsky , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Iugoslávia
15.
Asian Pac J Cancer Prev ; 15(24): 10779-82, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25605175

RESUMO

PURPOSE: Analysis of descriptive epidemiological characteristics of pancreatic cancer in Vojvodina, Serbia. MATERIALS AND METHODS: The study covers population of Vojvodina in the period from 2000 to 2009. The method used for data processing was the descriptive. The data, referring to a specified period of time, were analyzed from chronological and demographic aspects and according to histological diagnosis. RESULTS: In the period from 2000 to 2009, there were 2,108 registered cases of pancreatic cancer of which 1,886 had a fatal outcome. Standardized incidence rates varied between 5.7 and 9.1 per 100,000 population in males and between 4.2 and 5.3 in females. Linear incidence trends in males in the specified period of time, based on crude (r=0.7883, p<0.05) and standardized (r=0,6373, p<0,05) incidence rates, demonstrated increase. Annual percent increase in the crude incidence rate was 4.5% in males, and 2.8% in females. Age-standardized mortality rates varied between 5.2 and 7.5 per 100,000 population in males and 3.6 and 4.7 in females. Linear mortality trends in males in the specified period of time, based on crude (r=0.8795, p<0.05) and standardized (r=0.7669, p<0.05) mortality rates, also demonstrated annual percent increase. CONCLUSIONS: Data analysis shows unfavorable onco-epidemiological situation related to pancreatic cancer in Vojvodina, in aspects of both incidence and mortality. Absence of primary and secondary prevention does not allow medical institutions to successfully fight against this disease.


Assuntos
Adenocarcinoma/epidemiologia , Adenocarcinoma/mortalidade , Neoplasias Pancreáticas/epidemiologia , Neoplasias Pancreáticas/mortalidade , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Demografia , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Prognóstico , Sistema de Registros , Taxa de Sobrevida , Iugoslávia/epidemiologia
16.
Acta Med Hist Adriat ; 11(2): 237-50, 2013.
Artigo em Servo-Croata (Latino) | MEDLINE | ID: mdl-24304107

RESUMO

Ljubica Bosner, MD (2 February 1902 - 21 October 1990) was a distinguished woman surgeon, who worked in Rijeka, and all over Croatia, including the posts in Ogulin, Bjelovar, Petrinja, and VaraZdin, that are marginally known to wider medical circles and general public from her biography. Archive records point to her beginnings as a surgeon at the regional hospital of Ogulin in the 1930s, and then at the Department of Surgery and Gynaecology of the regional hospital and later state hospital of Bjelovar, where she had operated over the first two years of World War 2. From the end of 1942 to May 1943, she worked as a surgeon and the head of the hospital in Petrinja, and then as the head of the Soft Tissue Unit, Department of Surgery at Rebro Hospital in Zagreb until May 1945. She then headed the hospital in Mali Losinj until 1946 and moved to the Sobol Brothers Hospital in Rijeka, where she worked until retirement. Ljubica Bosner was one of the few women who had spent all her working life in general surgery, gynaecology and obstetrics, war surgery, and later paediatric surgery. Thousands of surgery records witness to her unrelenting dedication and high professionalism in regular as well as in emergency war situations. Her mentorship, loyalty to colleagues and medicine, social sensitivity and good will are still being recalled by her students.


Assuntos
Cirurgia Geral/história , Ginecologia/história , Obstetrícia/história , Croácia , História do Século XX , Iugoslávia
17.
Ned Tijdschr Geneeskd ; 157(27): A5958, 2013.
Artigo em Holandês | MEDLINE | ID: mdl-23838400

RESUMO

We report 2 cases of visceral leishmaniasis in Dutch patients after a stay in Greece and the former Yugoslavia, respectively. Patient A, a 69-year-old woman, was referred to our department with abdominal pain. Additional examinations were suggestive of chronic liver disease. After a liver biopsy, which demonstrated hepatic granulomas, we admitted the patient due to a sudden onset of cyclic fever. Patient B, a 50-year-old woman, was admitted with cyclic fever and abdominal pain. We treated the patient with IV antibiotics and discontinued the methotrexate treatment for her rheumatoid arthritis. Both patients were diagnosed with visceral leishmaniasis and treated with liposomal amphotericin-B. Patient A, an immunocompetent patient, had stayed in Greece for prolonged periods. Patient B had lived in the former Yugoslavia until 1999, and her methotrexate use had likely activated an asymptomatic Leishmania infection. Visceral leishmaniasis, a potentially lethal protozoan disease, should be considered in patients who have travelled in Southern Europe.


Assuntos
Dor Abdominal/diagnóstico , Anfotericina B/uso terapêutico , Antiprotozoários/uso terapêutico , Leishmania infantum/isolamento & purificação , Leishmaniose Visceral/diagnóstico , Dor Abdominal/tratamento farmacológico , Idoso , Artrite Reumatoide/tratamento farmacológico , Feminino , Grécia/etnologia , Humanos , Leishmaniose Visceral/tratamento farmacológico , Metotrexato/efeitos adversos , Metotrexato/uso terapêutico , Pessoa de Meia-Idade , Países Baixos , Viagem , Resultado do Tratamento , Iugoslávia/etnologia
18.
Med Glas (Zenica) ; 10(1): 106-12, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23348171

RESUMO

AIM: To compare clinical and cost outcomes of psoriasis in non-biological treatment of adherent and non-adherent patients in a developing Balkans country going through socio-economic transition. METHODS: The study was designed as a retrospective cohort study involving patients with psoriasis adherent and non-adherent to the prescribed treatment regimen. The patients were followed for a period of one year, through four visits with intervals of three months. The adherence to the prescribed regimen was measured at the end of the follow-up period by the medication possession ratio. Clinical outcomes of the treatment were estimated by the Psoriasis Area Severity Index (PASI) at each visit and the treatment costs were collected from patients' files at each visit. RESULTS: The study enrolled 108 patients, 61 (56.5%) were adherent to the prescribed treatment, and 47 (43.5%) were non-adherent. A signiicant decrease of PASI score was noted in the patients adherent to prescribed therapy (p < 0.001). The costs also decreased significantly in the group of adherent patients (p=0.001), and the drop of costs was the highest from the visit 3. The decrease in PASI score and costs were less rapid in non-adherent patients. CONCLUSION: Better treatment adherence leads to faster clinical improvement and a more rapid decrease in costs of treatment, which diminish overall expenditure of the health system and society, leaving room for treatment of other diseases more efficiently. Therefore, health systems of developing countries should support additional research of causes of treatment non-adherence in patients with psoriasis, in order to minimize this fenomenon more efficiently, and make significant savings.


Assuntos
Dietoterapia , Custos de Cuidados de Saúde , Cooperação do Paciente , Psoríase/economia , Psoríase/terapia , Adulto , Idoso , Consumo de Bebidas Alcoólicas/efeitos adversos , Índice de Massa Corporal , Café/efeitos adversos , Dietoterapia/estatística & dados numéricos , Feminino , Seguimentos , Custos de Cuidados de Saúde/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Cooperação do Paciente/estatística & dados numéricos , Psoríase/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Fumar/efeitos adversos , Resultado do Tratamento , Iugoslávia/epidemiologia
19.
Eur J Prev Cardiol ; 20(6): 1013-21, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22642981

RESUMO

BACKGROUND: Risk of cardiovascular disease varies between ethnic groups and the aim of this study was to investigate differences in cardiovascular risk factors, and total cardiovascular risk between ethnic groups in Norway. DESIGN: Cross-sectional study using data from the Cohort of Norway (CONOR). METHODS: A sample of 62,145 participants, 40-65 years of age, originating from 11 geographical regions, were included in our study. Self-reported variables, blood samples and physical measurements were used to estimate age- and time-adjusted mean values of cardiovascular risk factors for different ethnic groups. The 10-year risks of cardiovascular mortality and cardiovascular events were calculated using the Framingham and NORRISK risk models. RESULTS: We observed differences between ethnic groups for cardiovascular risk factors and both Framingham and NORRISK risk scores. NORRISK showed significant differences by ethnicity in women only. Immigrants from the Indian subcontinent had the lowest high-density lipoprotein (HDL) levels, the highest levels of blood glucose, triglycerides, total cholesterol/HDL ratio, waist hip ratio and diabetes prevalence. Immigrants from the former Yugoslavia had the highest Framingham scores, high blood pressure, high total cholesterol/HDL ratio, overweight measures and smoking. Low cardiovascular risk was observed among East Asian immigrants. CONCLUSION: The previously reported excess cardiovascular risk among immigrants from the Indian subcontinent was supported in this study. We also showed that immigrants from the former Yugoslavian countries had a higher total 10-year risk of cardiovascular events than other ethnic groups. This study adds information about ethnic groups in Norway which needs to be addressed in further research and targeted prevention strategies.


Assuntos
Doenças Cardiovasculares/etnologia , Emigrantes e Imigrantes , Etnicidade , Adulto , Idoso , Ásia/etnologia , Doenças Cardiovasculares/diagnóstico , Doenças Cardiovasculares/mortalidade , Estudos Transversais , Diabetes Mellitus/etnologia , Dislipidemias/etnologia , Feminino , Humanos , Hipertensão/etnologia , Índia/etnologia , Estilo de Vida/etnologia , Masculino , Pessoa de Meia-Idade , Noruega/epidemiologia , Obesidade/etnologia , Prevalência , Fatores de Risco , Fatores Sexuais , Fatores de Tempo , Iugoslávia/etnologia
20.
Int. j. morphol ; 30(3): 786-790, Sept. 2012. ilus
Artigo em Inglês | LILACS | ID: lil-665479

RESUMO

The goals of this study were to find the average intracranial capacity of the living male-entities of Kosovo Albanian population, to define cephalofacial indexes and their interrelations with intracranial capacity and to explore their latent structure. Eight cephalofacial variables have been measured in 571 male entities of the Kosovo Albanian population, aged 18-35 years old. Of these measurements, 6 cephalofacial indexes and intracranial capacity were calculated. According to the results of Table it can be concluded that most of Albanian males from Kosovo have long, wide and average height head, as well as most of them have brachiocephalic head, low hypsicephalic, and tapeinocephalic head, with intracranial capacity 1379.2cc. Regression Analyzes show that among other cephalofacial indexes, vertical cephalic index and transversal cephalic index have higher predictive influence on size of the intracranial capacity (VCI=1.764; TCI=-1.45).The possibility of the prediction of Intracranial Capacity (ICC) based on the values of VCI and TCI argues their joint projection on the first extracted latent factor, which has been nominated as factor of the head volume. The latent structure of the cephalofacial indexes consists of three latent factors: 1) factor of the head volume; 2) facial factor; 3) cephalic factor...


Los objetivos de este estudio fueron conocer la capacidad intracraneal (CIC) media en hombres de población Albanesa de Kosovo, para definir los índices cefalofaciales y sus interrelaciones con la CIC, así como para explorar su estructura latente. Ocho variables cefalofaciales fueron medidas en 571 hombres de población Albanesa de Kosovo, con edades entre 18-35 años. A partir de estas mediciones se calcularon 6 índices cefalofaciales y CIC. De acuerdo con el primer objetivo, la mayoría de los hombres Albaneses de Kosovo tienen una cabeza larga, ancha y de altura media, así como la mayoría de ellos son braquiocefálicos, hipsicefálicos leves y de cabeza tapeinocefálica, con CIC de 1379,2cc. El análisis de regresión muestra que entre otros índices cefalofaciales, el índice cefálico vertical (ICV) e índice cefálico transversal (ICT) tienen la mayor influencia de predicción del tamaño de la capacidad intracraneal (ICV = 1,764; ICT = -1,45). La posibilidad de la predicción del ICV e ICT sobre la CIC, argumentan su proyección (junto con CIC) sobre el primer factor latente extraído, el cual ha sido denominado factor del volumen de la cabeza. La estructura latente de los índices cefalofaciales está constituida por tres factores latentes: 1) el factor del volumen de la cabeza, 2) el factor facial y 3) el factor cefálico...


Assuntos
Humanos , Masculino , Adolescente , Adulto , Adulto Jovem , Cefalometria , Crânio/anatomia & histologia , Encéfalo/anatomia & histologia , Albânia , Análise Fatorial , Tamanho do Órgão , Análise de Regressão , Iugoslávia
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