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2.
Ann Vasc Surg ; 66: 171-178, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31705993

RESUMO

BACKGROUND: Frailty, characterized by physiologic depletion, predicts postoperative morbidity and mortality in vascular surgery patients. CT-derived sarcopenia is a valuable method for objectively staging frailty preoperatively. PURPOSE: With prior analyses primarily measuring psoas cross-sectional area on CT, we compared a method of measuring thoracic sarcopenia to existing techniques of lumbar sarcopenia and assessed the association with long-term survival and outcomes post-Thoracic Endovascular Aortic Repair (TEVAR). METHODS: Prospectively collected data of 217 patients undergoing TEVAR from 2009 to 2012 were reviewed. Thoracic sarcopenia was quantified by measuring total area of the rectus abdominis, latissimus dorsi, intercostal, erector spinae, and external and internal oblique muscles at the T12 vertebral level. Total psoas area at the L3 was used to measure lumbar sarcopenia. RESULTS: 200 patients had preoperative imaging enabling measurements of thoracic sarcopenia, 186 of these patients were also assessed for lumbar sarcopenia. Thoracic sarcopenic patients were older, had lower body mass indices, were more commonly female, and most commonly being treated for aneurysms. Thoracic sarcopenic patients had significantly higher rates of congestive heart failure, hypertension, prior vascular intervention, and TEVAR-related adverse events. Thoracic sarcopenia was associated with significantly higher mortality at 2 and 5 years post-TEVAR (2-year mortality: 19% vs 8%, P = 0.02; 5-year mortality: 31% vs 18%, P = 0.03). Lumbar sarcopenia was not associated with increased mortality at any time point. Patients whose muscle mass degraded over 48-month follow-up did not experience significantly higher rates of adverse events. CONCLUSIONS: CT-derived thoracic sarcopenia, but not lumbar sarcopenia, is significantly associated with 5-year mortality post-TEVAR.


Assuntos
Aorta Torácica/cirurgia , Doenças da Aorta/cirurgia , Implante de Prótese Vascular/mortalidade , Procedimentos Endovasculares/mortalidade , Músculo Esquelético/diagnóstico por imagem , Sarcopenia/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Músculos Abdominais Oblíquos/diagnóstico por imagem , Adulto , Idoso , Aorta Torácica/diagnóstico por imagem , Doenças da Aorta/diagnóstico por imagem , Doenças da Aorta/mortalidade , Implante de Prótese Vascular/efeitos adversos , Composição Corporal , Ensaios Clínicos como Assunto , Procedimentos Endovasculares/efeitos adversos , Feminino , Nível de Saúde , Humanos , Músculos Intercostais/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Reto do Abdome/diagnóstico por imagem , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Sarcopenia/mortalidade , Sarcopenia/fisiopatologia , Músculos Superficiais do Dorso/diagnóstico por imagem , Fatores de Tempo , Resultado do Tratamento
3.
Surg Endosc ; 32(5): 2474-2479, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29264755

RESUMO

BACKGROUND: Component separation (CS) is a technique which mobilizes flaps of innervated, vascularized tissue, enabling closure of large ventral hernia defects using autologous tissue. Disadvantages include extensive tissue dissection when creating these myofascial advancement flaps, with potential consequences of significant post-operative skin and wound complications. This study examines the benefit of a novel, ultra-minimally invasive single port anterior CS technique. METHODS: This was a prospective study of 16 external oblique (EO) releases performed in 9 patients and 4 releases performed in 3 fresh frozen cadavers. All patients presented with recurrent complex ventral hernias, and were administered preoperative Botulinum Toxin A to their lateral oblique muscles to facilitate defect closure. At the time of elective laparoscopic repair, patients underwent single port endoscopic EO release using a single 20-mm incision on each side of the abdomen. Measurements were taken using real-time ultrasound. Postoperatively, patients underwent serial examination and abdominal CT assessment. RESULTS: Single port endoscopic EO release achieved a maximum of 50-mm myofascial advancement per side (measured at the umbilicus). No complications involving wound infection, hematoma, or laxity/bulge have been noted. All patients proceeded to laparoscopic or laparoscopic-open-laparoscopic intraperitoneal mesh repair of their hernia, with no hernia recurrences to date. CONCLUSIONS: Single port endoscopic EO release holds potential as an adjunct in the repair of large ventral hernia defects. It is easy to perform, is safe and efficient, and entails minimal disruption of tissue planes and preserves abdominal wall perforating vessels. It requires only one port-sized incision on each side of the abdomen, thus minimizing potential for complications. Further detailed quantification of advancement gains and morbidity from this technique is warranted, both with and without prior administration of Botulinum Toxin A to facilitate closure.


Assuntos
Músculos Abdominais Oblíquos/cirurgia , Endoscopia , Hérnia Ventral/cirurgia , Músculos Abdominais Oblíquos/diagnóstico por imagem , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Laparoscopia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Ultrassonografia
4.
Clin Nucl Med ; 42(10): 782-783, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28806250

RESUMO

A Tc-MDP bone scintigraphy was performed in an 88-year-old man with a history of right external oblique muscle leiomyosarcoma, which was resected 8 months ago. The static images showed abnormal tracer uptake in the region of resection bed. SPECT/CT images demonstrated that the increased activity was from a partially calcified soft tissue mass in external oblique muscle. Subsequent pathological examination confirmed recurrent tumor.


Assuntos
Músculos Abdominais Oblíquos/diagnóstico por imagem , Leiomiossarcoma/diagnóstico por imagem , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único , Medronato de Tecnécio Tc 99m , Idoso de 80 Anos ou mais , Humanos , Masculino , Recidiva
5.
Masui ; 65(12): 1276-1278, 2016 12.
Artigo em Japonês | MEDLINE | ID: mdl-30379470

RESUMO

A 41-year-old female patient with no remarkable medical history underwent a uterine myomectomy under general anesthesia. Ultrasound-guided lateral TAP block was performed using a 21-gauge blunt needle after surgery. Heparin calcium at 5,000 units was administered subcutaneously twice on postopera- tive day (POD)Y 1, and fondaparinux at 2.5 mg was administered subcutaneously once daily from POD 2 to POD 5. On POD 3, right-sided flank pain was noticed, which persisted until POD 7. Abdominal ultrasonogra- phy revealed an abdominal oblique muscle hematoma with a size of 43x19x31 mm. The patient had no anemia, and was discharged on POD 8. Right-sided flank pain disappeared, and the hematoma could not be identified by ultrasonography on POD 20.


Assuntos
Músculos Abdominais Oblíquos/diagnóstico por imagem , Hematoma/etiologia , Bloqueio Nervoso/efeitos adversos , Adulto , Anestesia Geral , Feminino , Hematoma/diagnóstico por imagem , Humanos , Dor Pós-Operatória , Ultrassonografia , Ultrassonografia de Intervenção/efeitos adversos
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