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1.
J Int Adv Otol ; 20(3): 225-230, 2024 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-39158317

RESUMO

The aim of this article is to determine the efficacy of otoendoscopy during microscopic cholesteatoma surgery on residual cholesteatoma rates postoperatively. The medical records of patients (aged 4-90) with primary acquired cholesteatoma who underwent microscopic cholesteatoma surgery (exclusively transcanal approach or canal wall-up tympano-mastoidectomy) with subsequent otoendoscopic examination (80 ears) for intraoperative cholesteatoma residues were retrospectively reviewed. All cases with mixed microscopic/endoscopic, fully endoscopic, or fully microscopic dissection were excluded, as well as cases where a canal wall-down technique was used. After microscopic cholesteatoma removal, the otoendoscope was used to inspect the middle ear recesses for intraoperative cholesteatoma residues. The intra- and postoperative cholesteatoma residue rate were evaluated. On endoscopic examination, intraoperative cholesteatoma residues were encountered in 24 patients (30%). A total of 30 foci were detected. Most of them were found in the superior retrotympanum (15 foci). In 9 cases an antral remnant guided the surgeon to convert to a canal wall up tympanomastoidectomy. During the postoperative follow-up period, residual cholesteatoma was detected on postoperative magnetic resonance imaging in 6 patients (7.5%). Adding an otoendoscopic examination to microscopic cholesteatoma surgery reduced the postoperative cholesteatoma residues rate (odds ratio=0.16). A negative otoendoscopic examination led to a cholesteatoma residue-free follow-up period in 95% of cases(NPV=0.95). Otoendoscopy is effective in identifying intraoperative cholesteatoma residues after microscopic cholesteatoma surgery. It reduces the postoperative cholesteatoma residue rate, and a negative otoendoscopic examination increases the likelihood of a cholesteatoma residue-free follow-up.


Assuntos
Colesteatoma da Orelha Média , Endoscopia , Humanos , Colesteatoma da Orelha Média/cirurgia , Colesteatoma da Orelha Média/patologia , Idoso , Criança , Masculino , Feminino , Estudos Retrospectivos , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Adulto , Adolescente , Pré-Escolar , Endoscopia/métodos , Adulto Jovem , Resultado do Tratamento , Otoscopia/métodos , Mastoidectomia/métodos , Procedimentos Cirúrgicos Otológicos/métodos , Microcirurgia/métodos , Doença Crônica
2.
J Int Adv Otol ; 20(3): 231-235, 2024 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-39158348

RESUMO

Although advanced technologies and surgical procedures are used, cholesteatoma is a disease with the possibility of recurrence. The aim of this study was to determine the long-term effect of sodium 2-mercaptoethane sulfonate (MESNA) on cholesteatoma surgery. Patients who underwent cholesteatoma surgery between January 2009 and July 2014 by the same surgeon were divided into 2 groups: those where MESNA was used and those where it was not. Otomicroscopic examinations were performed to see the presence of cholesteatoma recurrence in the patients who had surgery at least 8 years ago. Pure-tone audiometry was performed to evaluate the hearing results. Sodium 2-mercaptoethane sulfonate was used in 23 patients and was not used in 39 patients who came to the control. In the MESNAused group, cholesteatoma was seen in only 1 of the patients who underwent a canal wall-down (CWD) mastoidectomy. In the MESNA non-used group, cholesteatoma was seen in 3 patients who underwent CWD. The difference was not statistically significant. Although there was no statistically significant difference, recurrence of cholesteatoma was seen less frequently in patients who received MESNA during surgery. Studies to be conducted in larger patient series may clarify this issue.


Assuntos
Colesteatoma da Orelha Média , Mastoidectomia , Mesna , Recidiva , Humanos , Colesteatoma da Orelha Média/cirurgia , Feminino , Masculino , Adulto , Pessoa de Meia-Idade , Mesna/uso terapêutico , Mesna/administração & dosagem , Resultado do Tratamento , Mastoidectomia/métodos , Audiometria de Tons Puros , Adolescente , Adulto Jovem , Estudos Retrospectivos , Idoso , Criança
3.
J Int Adv Otol ; 20(4): 325-330, 2024 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-39161175

RESUMO

This study aimed to compare total endoscopic ear surgery (TEES) and microscopic postauricular canal-wall-down tympanomastoidectomy (CWD) in cholesteatoma surgery in our clinic. This study included 59 patients, of whom 30 and 29 were operated on with CWD in 2016-2018 and TEES in 2019-2021, respectively and compared regarding intraoperative findings, hearing outcomes, long-term outcomes, and recidivism rates between groups. This study excluded patients in stage IV according to the European Academy of Otology and Neurotology/Japan Otological Society Staging System on Middle Ear Cholesteatoma, aged < 18, with congenital cholesteatoma, who underwent revision surgery. Two patients in the TEES group had recidivism (6.9%), with recurrent disease observed in both patients and residual disease in none, whereas 3 patients in the CWD group had recidivism (10%), including recurrent disease in 2 and residual disease in 1 patient. Tympanic membrane perforation occurred in 2 (6.9%) and 1 (3.3%) patients in the TEES and CWD groups, respectively. The 2 groups revealed no significant difference in terms of recidivism and perforation rates (P=1.000, P = .612). The CWD group had a longer mean operation time (225.54 ± 47.86 minutes) than the TEES group (160.55 ± 24.98 minutes) (P < .001). The 2 groups demonstrated no significant difference regarding pre- and postoperative air-bone gap (ABG) and ABG gain (P = .105, P=.329, P=.82, respectively). Total endoscopic ear surgery provides similar results in terms of hearing, recidivism, and long-term outcomes with the microscopic CWD approach. However, the CWD approach is still important, especially in patients in advanced stages.


Assuntos
Colesteatoma da Orelha Média , Endoscopia , Mastoidectomia , Humanos , Masculino , Feminino , Colesteatoma da Orelha Média/cirurgia , Endoscopia/métodos , Adulto , Pessoa de Meia-Idade , Resultado do Tratamento , Mastoidectomia/métodos , Procedimentos Cirúrgicos Otológicos/métodos , Recidiva , Estudos Retrospectivos , Meato Acústico Externo/cirurgia , Meato Acústico Externo/patologia , Adulto Jovem , Adolescente , Idoso , Timpanoplastia/métodos
4.
J Int Adv Otol ; 20(4): 372-374, 2024 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-39162066

RESUMO

Hemangioma is a common vascular neoplasm that arises in the head and neck regions but is rare in the petrous bone. We report the first case of a solitary cavernous hemangioma in the mastoid antrum. A 68-year-old woman visited our hospital with a complaint of tinnitus without any other symptoms. Tinnitus of the right ear occurred especially when the patient yawned or swallowed. Both tympanic membranes appeared normal on otoscopic examination. On pure-tone audiometry, mild hearing loss up to 25 dB was detected in the right ear. Temporal bone computed tomography revealed a 7.0 mm × 4.5 mm × 5 mm, solitary soft tissue mass in the aditus ad antrum. Excisional biopsy was performed under general anesthesia through the canal wall as in a mastoidectomy. The mass was completely removed without any bleeding or ossicular chain damage. The mass was confirmed as a cavernous hemangioma. During follow-up, the patient's tinnitus and right low-tone hearing loss improved. No solitary hemangioma of the mastoid antrum has been reported previously. Surgical excision of the lesion appears to be proper treatment to achieve pathologic confirmation along with resolution of symptoms.


Assuntos
Hemangioma Cavernoso , Processo Mastoide , Zumbido , Humanos , Feminino , Idoso , Hemangioma Cavernoso/cirurgia , Hemangioma Cavernoso/patologia , Hemangioma Cavernoso/diagnóstico por imagem , Hemangioma Cavernoso/diagnóstico , Processo Mastoide/cirurgia , Processo Mastoide/patologia , Zumbido/etiologia , Mastoidectomia/métodos , Tomografia Computadorizada por Raios X , Audiometria de Tons Puros/métodos , Neoplasias Cranianas/cirurgia , Neoplasias Cranianas/patologia , Neoplasias Cranianas/diagnóstico , Neoplasias Cranianas/diagnóstico por imagem , Resultado do Tratamento
5.
Artigo em Chinês | MEDLINE | ID: mdl-38973032

RESUMO

Objective:To investigate the changes in hearing threshold of the acquired primary cholesteatoma of the middle ear with different degrees of eustachian tube dysfunction after balloon eustachian tuboplasty. Methods:This retrospective study included forty cases with middle ear cholesteatoma and eustachian tube dysfunction who underwent open mastoidectomy + tympanoplasty + balloon eustachian tuboplasty were enrolled. All patients were admitted from November 2020 to April 2022. The preoperative eustachian tube score of 0-2 were defined as the lower group, and the scores of 3-5 were defined as the higher group. Pure tone audiometry was measured preoperatively and 1, 3, 6 and 12 months postoperatively. The average value of bone conduction threshold and air conduction threshold of 250-4 000 Hz were calculated, and the air-bone gap was calculated simultaneously. SPSS 25.0 was used for statistical analysis. P<0.05 was considered statistically significant. Results:In the lower group, the air conduction threshold and air-bone gap at 3 months postoperatively were significantly decreased in comparison with those preoperatively(P<0.05),as was the air-bone gap at 6 months postoperatively(P<0.05). In the higher group, the air conduction threshold and air-bone gap were significantly decreased at 3, 6 and 12 months postoperatively(P<0.05). Conclusion:The air conduction threshold and air-bone gap of patients with the acquired primary cholesteatoma of the middle ear and eustachian tube dysfunction were significantly decreased after eustachian tube balloon dilatation. Hearing improvement lasted longer in patients with slight eustachian tube dysfunction.


Assuntos
Audiometria de Tons Puros , Colesteatoma da Orelha Média , Tuba Auditiva , Timpanoplastia , Humanos , Tuba Auditiva/fisiopatologia , Tuba Auditiva/cirurgia , Estudos Retrospectivos , Feminino , Colesteatoma da Orelha Média/cirurgia , Masculino , Timpanoplastia/métodos , Adulto , Pessoa de Meia-Idade , Limiar Auditivo , Mastoidectomia/métodos , Condução Óssea
6.
Artigo em Chinês | MEDLINE | ID: mdl-38973037

RESUMO

Objective:To analyze the surgical efficacy and safety of tympanoplasty with and without mastoidectomy for the treatment of active simple chronic suppurative otitis media(CSOM), and to investigate whether mastoidectomy can be avoided in tympanoplasty for active CSOM. Methods:The clinical data of 55 patients(55 ears) with active CSOM were retrospectively analyzed. Based on the development of the mastoid process and the upper tympanic chamber, patients who met the criteria for wall-up mastoidectomy were classified as group A (30 patients), and underwent tympanoplasty combined with wall-up mastoidectomy. Patients who did not meet the criteria for wall-up mastoidectomy were classified as group B(25 cases), and underwent tympanoplasty with the opening of the middle and upper tympanic chambers and sinus drainage after partial removal of the shield plate bone. The survival rate of tympanic membrane grafts, hearing before and after surgery, and complications such as reperforation were compared between the two groups at 3 months postoperatively. Results:The overall postoperative tympanic membrane survival rate of patients with active CSOM was 96.4%(53/55), including 96.7% in group A; 96.0% in group B. There was no significant difference in the tympanic membrane survival rate between the two groups(P>0.05). The postoperative mean air-bone gap(ABG) was significantly reduced in both groups compared with the preoperative period, but there was no significant difference in ABG gain between the two groups(P>0.05). No patients experienced serious adverse conditions such as peripheral facial paralysis, cerebrospinal fluid leakage, or sensorineural deafness after surgery. Conclusion:Microscopic tympanoplasty with patency of the middle and upper tympanic chambers and tympanic sinus drainage can be used to treat active simple chronic otitis media with satisfactory tympanic membrane viability and hearing improvement efficacy. This approach reduces patient trauma, prevents complications such as skin depressions in the mastoid area due to abrasion of the mastoid bone, and shortens the waiting time before surgery.


Assuntos
Mastoidectomia , Otite Média Supurativa , Timpanoplastia , Humanos , Otite Média Supurativa/cirurgia , Timpanoplastia/métodos , Estudos Retrospectivos , Mastoidectomia/métodos , Masculino , Feminino , Resultado do Tratamento , Doença Crônica , Pessoa de Meia-Idade , Adulto , Membrana Timpânica/cirurgia , Processo Mastoide/cirurgia
7.
Am J Otolaryngol ; 45(5): 104411, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39059170

RESUMO

OBJECTIVE: To suggest a comprehensive algorithm for the surgical approach for correcting of sources of temporal bone CSF leaks. METHODS: A case series for patients operated in a single academic tertiary referral center between 2011 and 4.2022. Included in the study were 46 patients, 5 of whom had a bilateral problem, resulting in 51 pathologic temporal bones. The presentation was an active CSF leak (38 patients) or bacterial otogenic meningitis (8 patients). Follow up ranged from 8 months to 5 years. RESULTS: Of the 42 ears operated via the default middle fossa approach, 37 were successful (88 %) in controlling CSF leak. None had intracranial complications or sensorineural hearing loss. Location, number and size of the defects, hearing status, associated superior semicircular canal dehiscence, additional intra-temporal or intra-cranial pathologies may indicate a transmastoid approach. Of the six ears that had a canal wall up mastoidectomy as a primary procedure, one required revision due to ongoing CSF leak. Five revision cases and three primary cases were effectively sealed with a subtotal petrosectomy and obliteration. One was lost to follow-up. Hearing was reconstructed with bone-anchored hearing implants in 6 out of these 8 ears. CONCLUSIONS: The middle fossa approach could be used as a default approach for sealing TD. There are a number of indications for transmastoid approaches in both primary and revision cases. Obliteration of the ear was used in all revision cases. The suggested algorithm can help in planning surgery for temporal bone CSF leaks or a history of otogenic meningitis.


Assuntos
Algoritmos , Vazamento de Líquido Cefalorraquidiano , Osso Temporal , Humanos , Osso Temporal/cirurgia , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Vazamento de Líquido Cefalorraquidiano/cirurgia , Vazamento de Líquido Cefalorraquidiano/etiologia , Resultado do Tratamento , Idoso , Seguimentos , Adulto Jovem , Meningites Bacterianas/cirurgia , Mastoidectomia/métodos , Estudos Retrospectivos , Adolescente , Procedimentos Cirúrgicos Otológicos/métodos
8.
BMJ Open ; 14(5): e087062, 2024 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-38806427

RESUMO

INTRODUCTION: Radical mastoidectomy is a common procedure for chronic suppurative otitis media, typically performed under a microscope. The smooth operation is closely related to the clarity of the operative field. Our trial is designed to investigate whether the intravenous administration of tranexamic acid (TXA) can improve the clarity of the operative field, reduce the operative time, and increase surgeon satisfaction. METHODS AND ANALYSIS: This study is a prospective, randomised, double-blinded, controlled trial that aims to investigate the effects of TXA on patients with otitis media. The trial will include patients between the ages of 18 and 65 who will be randomly assigned to either the TXA group or the control group. In the TXA group, patients will receive 1 g of TXA diluted to 20 mL of normal saline before anaesthesia induction while the control group will receive 20 mL of normal saline. The primary outcome measure will be the Modena Bleeding Score, which will assess the clarity of the surgical field. Secondary outcomes will include the surgeon's satisfaction with surgical conditions, operation time, laboratory measurements (prothrombin time, activated partial thromboplastin time, fibrin degradation products, D-dimer) and levels of inflammatory factors (such as IL-6) at 24 hours postoperatively. In addition, the incidence of general adverse reactions such as postoperative nausea, vomiting and dizziness; serious adverse events such as arterial and venous thromboembolism, myocardial infarction and epilepsy within 90 days will be compared between the two groups. ETHICS AND DISSEMINATION: The protocol was approved by the Ethics Committee of Peking University People's Hospital (2021PHB173-001), on 19 July 2021. The trial results will be submitted for publication in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ChiCTR2100049183.


Assuntos
Administração Intravenosa , Antifibrinolíticos , Mastoidectomia , Ácido Tranexâmico , Humanos , Ácido Tranexâmico/administração & dosagem , Ácido Tranexâmico/uso terapêutico , Ácido Tranexâmico/efeitos adversos , Método Duplo-Cego , Antifibrinolíticos/administração & dosagem , Antifibrinolíticos/uso terapêutico , Estudos Prospectivos , Adulto , Mastoidectomia/métodos , Pessoa de Meia-Idade , Feminino , Masculino , Adolescente , Otite Média Supurativa/cirurgia , Otite Média Supurativa/tratamento farmacológico , Adulto Jovem , Ensaios Clínicos Controlados Aleatórios como Assunto , Duração da Cirurgia , Idoso
9.
Int J Comput Assist Radiol Surg ; 19(7): 1273-1280, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38816649

RESUMO

PURPOSE: Skullbase surgery demands exceptional precision when removing bone in the lateral skull base. Robotic assistance can alleviate the effect of human sensory-motor limitations. However, the stiffness and inertia of the robot can significantly impact the surgeon's perception and control of the tool-to-tissue interaction forces. METHODS: We present a situational-aware, force control technique aimed at regulating interaction forces during robot-assisted skullbase drilling. The contextual interaction information derived from the digital twin environment is used to enhance sensory perception and suppress undesired high forces. RESULTS: To validate our approach, we conducted initial feasibility experiments involving a medical and two engineering students. The experiment focused on further drilling around critical structures following cortical mastoidectomy. The experiment results demonstrate that robotic assistance coupled with our proposed control scheme effectively limited undesired interaction forces when compared to robotic assistance without the proposed force control. CONCLUSIONS: The proposed force control techniques show promise in significantly reducing undesired interaction forces during robot-assisted skullbase surgery. These findings contribute to the ongoing efforts to enhance surgical precision and safety in complex procedures involving the lateral skull base.


Assuntos
Procedimentos Cirúrgicos Robóticos , Base do Crânio , Humanos , Base do Crânio/cirurgia , Procedimentos Cirúrgicos Robóticos/métodos , Estudos de Viabilidade , Mastoidectomia/métodos
10.
Ann Otol Rhinol Laryngol ; 133(7): 665-671, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38676449

RESUMO

OBJECTIVE: To compare the cost-effectiveness of serial non-echo planar diffusion weighted MRI (non-EP DW MRI) versus planned second look surgery following initial canal wall up tympanomastoidectomy for the treatment of cholesteatoma. METHODS: A decision-analytic model was developed. Model inputs including residual cholesteatoma rates, rates of non-EP DW MRI positivity after surgery, and health utility scores were abstracted from published literature. Cost data were derived from the 2022 Centers for Medicare and Medicaid Services fee rates. Efficacy was defined as increase in quality-adjusted life year (QALY). One- and 2-way sensitivity analyses were performed on variables of interest to probe the model. Total time horizon was 50 years with a willingness to pay (WTP) threshold set at $50 000/QALY. RESULTS: Base case analysis revealed that planned second-look surgery ($11 537, 17.30 QALY) and imaging surveillance with non-EP DWMRI ($10 439, 17.26 QALY) were both cost effective options. Incremental cost effectiveness ratio was $27 298/QALY, which is below the WTP threhshold. One-way sensitivity analyses showed that non-EP DW MRI was more cost effective than planned second-look surgery if the rate of residual disease after surgery increased to 48.3% or if the rate of positive MRI was below 45.9%. A probabilistic sensitivity analysis at WTP of $50 000/QALY found that second-look surgery was more cost-effective in 56.7% of iterations. CONCLUSION: Non-EP DW MRI surveillance is a cost-effect alternative to planned second-look surgery following primary canal wall up tympanomastoidectomy for cholesteatoma. Cholesteatoma surveillance decisions after initial canal wall up tympanomastoidectomy should be individualized. LEVEL OF EVIDENCE: V.


Assuntos
Colesteatoma da Orelha Média , Análise Custo-Benefício , Imagem de Difusão por Ressonância Magnética , Anos de Vida Ajustados por Qualidade de Vida , Cirurgia de Second-Look , Humanos , Cirurgia de Second-Look/economia , Imagem de Difusão por Ressonância Magnética/economia , Imagem de Difusão por Ressonância Magnética/métodos , Colesteatoma da Orelha Média/cirurgia , Colesteatoma da Orelha Média/diagnóstico por imagem , Colesteatoma da Orelha Média/economia , Mastoidectomia/economia , Mastoidectomia/métodos , Técnicas de Apoio para a Decisão , Estados Unidos
11.
Am J Otolaryngol ; 45(4): 104299, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38657531

RESUMO

INTRODUCTION: Acute mastoiditis (AM) can rapidly become life-threatening with various intracranial complications. The standard care includes antibiotics, mastoidectomy, and drainage. Reports show varying preferences for conservative and surgical treatments, with a more conservative approach gaining popularity. In this study we aim to evaluate the presenting symptoms, management and outcomes of patients presenting with intracranial complications secondary to acute mastoiditis. METHODS: Retrospective review for all children admitted for acute mastoiditis for 12 years period (January 2010-December 2021). Children who had mastoiditis associated with intracranial complications were included in the study. STROBE guidelines were followed in this study. RESULTS: 23 patients were diagnosed with acute mastoiditis with intracranial complications. The mean age was 2.1 years. The most common presenting sign was fever, followed by otalgia. The most common pathogens were Fusobacterium necrophorum and Streptococcus pneumoniae. The most common intracranial complication was sinus vein thrombosis (SVT) affecting 13 patients. Eventually, 10 patients underwent cortical mastoidectomy during 1-6 days upon admission, with an average of 3.2 days. During the follow-up period patients were monitored for clinical progression. Patients who did not show clinical improvement such as persistent fever, worsening symptoms, or the presence of neurological symptoms were treated surgically. The length of stay was an average of 15.5 days overall, with no significantly longer hospital stay in patients who were treated surgically compared to patients who were treated conservatively (17.1 days vs. 14.2 days, P = .26). CONCLUSION: Intracranial complications of acute mastoiditis remain a significant challenge. Selected patients with intracranial complications can be treated conservatively with close monitoring, without increasing the risk of immediate or long-term complications. Initial antimicrobial treatment should cover anaerobic bacteria, as it correlates with severe complications.


Assuntos
Mastoidite , Humanos , Mastoidite/terapia , Mastoidite/microbiologia , Mastoidite/complicações , Mastoidite/etiologia , Masculino , Feminino , Pré-Escolar , Doença Aguda , Estudos Retrospectivos , Criança , Lactente , Mastoidectomia/métodos , Antibacterianos/uso terapêutico , Trombose dos Seios Intracranianos/etiologia , Trombose dos Seios Intracranianos/terapia , Dor de Orelha/etiologia , Febre/etiologia , Tempo de Internação , Resultado do Tratamento
12.
Eur Arch Otorhinolaryngol ; 281(9): 4611-4615, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38642086

RESUMO

PURPOSE: The definitive treatment for chronic suppurative otitis media is surgery. Surgical technique and procedure varies according to individual case findings and pathology and may require mastoidectomies in which the canal wall is preserved or lowered to eradicate disease from mastoid air cells. Surgical treatment of chronic middle ear disease carries a risk of damage to the inner ear. The aim of this study was to investigate whether the noise produced by the tour system following chronic ear surgery causes sensorineural hearing loss, a condition for which not many studies have been published in the literature. METHODS: The study consisted of a total of 49 patients with type I, type II and type III canal wall preservation and 62 patients with tympanoplasty with canal wall preservation and lowering. Bone and air thresholds were compared before and after middle ear surgery. Changes in bone and air thresholds were compared according to the type of tympanoplasty. RESULTS: In the ICW-I, ICW-II and ICW-III tympanoplasties, and in the ICW and CWD tympanoplasties, the preoperative and postoperative values of the opposite ear hearing measurements were performed, and did not differ according to the type of surgery. There is no correlation drilling duration and hearing for the opposite ear. CONCLUSION: The prevention of postoperative sensorineural hearing loss depends on multiple factors, and assessing the magnitude of hearing loss in relation to these factors is important in determining the success of the surgery.


Assuntos
Perda Auditiva Neurossensorial , Mastoidectomia , Otite Média Supurativa , Timpanoplastia , Humanos , Timpanoplastia/métodos , Masculino , Feminino , Mastoidectomia/métodos , Adulto , Pessoa de Meia-Idade , Otite Média Supurativa/cirurgia , Perda Auditiva Neurossensorial/etiologia , Perda Auditiva Neurossensorial/cirurgia , Doença Crônica , Adolescente , Adulto Jovem , Idoso , Complicações Pós-Operatórias/etiologia , Limiar Auditivo , Fatores de Risco , Audiometria de Tons Puros
13.
Am J Otolaryngol ; 45(4): 104263, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38547748

RESUMO

OBJECTIVES: To describe a rare complication of cholesteatoma. METHODS: Case report with literature review. RESULTS: We report a case of a 37-year-old male who presented for evaluation of otorrhea, headache, and progressive left sensorineural hearing loss. Clinical and radiologic evaluation demonstrated a large recurrent attic cholesteatoma with erosion into the lateral and superior semicircular canals, and diffuse enhancement of the internal auditory canal and cerebellopontine angle suggestive of hypertrophic pachymeningitis secondary to cholesteatoma. After treatment with a course of antibiotics and canal wall down mastoidectomy surgery for cholesteatoma exteriorization, he experienced improvement of his symptoms and resolution of hypertrophic pachymeningitis. CONCLUSION: Hypertrophic pachymeningitis is a rarely described complication of cholesteatoma. In the context of cholesteatoma, treatment with antibiotics and surgical removal or exteriorization of cholesteatoma are effective treatments for HP.


Assuntos
Ângulo Cerebelopontino , Colesteatoma da Orelha Média , Hipertrofia , Meningite , Humanos , Masculino , Adulto , Meningite/etiologia , Meningite/complicações , Ângulo Cerebelopontino/cirurgia , Ângulo Cerebelopontino/diagnóstico por imagem , Colesteatoma da Orelha Média/complicações , Colesteatoma da Orelha Média/cirurgia , Recidiva , Orelha Interna/diagnóstico por imagem , Orelha Interna/cirurgia , Imageamento por Ressonância Magnética , Mastoidectomia/métodos , Tomografia Computadorizada por Raios X
14.
Int J Surg ; 110(7): 4170-4175, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38518079

RESUMO

BACKGROUND: The microscopic middle ear surgery involves a limited operating space and numerous important anatomical structures in which good visualization is crucial, as even a small amount of bleeding can greatly affect the clarity of surgical field. This study aims to investigate whether intravenous 1 g of tranexamic acid can improve surgical visualization and further shorten the operation time in microscopic middle ear surgery. METHODS: This study is a prospective, randomized, double-blind, controlled trial conducted from December 2021 to December 2022, enrolling patients who were scheduled for microscopic modified radical mastoidectomy due to chronic otitis media. In addition to standard techniques to optimize the surgical field, participants were randomized into the TXA (tranexamic acid) group (1 g diluted to 20 ml normal saline) and the control group (20 ml normal saline). The primary outcome was assessed based on the clarity of the surgical field using the Modena Bleeding Score. Secondary outcomes included operation time, the surgeon satisfaction with the visual clarity, postoperative 24 h coagulation parameters, and the incidence of adverse events. Student's t -test, χ2 test, and ANOVA of repeated measures were used for statistical analyses. RESULTS: A total of 28 patients were enrolled in each group using a 1:1 randomized allocation with similar demographic characteristics, including 24 male and 32 female individuals, and the mean age is 45.6±11.9 years. The surgical visualization in the TXA group was significantly better than that of the control group (2.29±0.46 vs. 2.89±0.31, P <0.001) as assessed by the Modena Bleeding Score. Furthermore, the TXA group demonstrated a shorter operation time compared to the control group (88.61±10.9 vs. 105.2±15.9, P <0.001) and higher surgeon satisfaction with surgical field (7.82±0.55 vs. 6.50±0.64, P <0.001). No statistically significant differences were found in postoperative coagulation parameters in the two groups. No TXA-related adverse events or complications occurred during the 12-month follow-up. CONCLUSION: Intravenous 1 g of TXA can further significantly improve the visual clarity in the microscopic middle ear surgery and shorten the operation time based on other standard measures implemented.


Assuntos
Antifibrinolíticos , Orelha Média , Duração da Cirurgia , Ácido Tranexâmico , Humanos , Ácido Tranexâmico/administração & dosagem , Masculino , Feminino , Método Duplo-Cego , Pessoa de Meia-Idade , Adulto , Antifibrinolíticos/administração & dosagem , Estudos Prospectivos , Orelha Média/cirurgia , Procedimentos Cirúrgicos Otológicos/métodos , Microcirurgia/métodos , Administração Intravenosa , Perda Sanguínea Cirúrgica/prevenção & controle , Otite Média/cirurgia , Mastoidectomia/métodos
15.
Otol Neurotol ; 45(4): 410-414, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38437812

RESUMO

OBJECTIVES: The operating microscope (OM) commonly used in ear surgeries has several disadvantages, including a low depth of field, a narrow field of view, and unfavorable ergonomic characteristics. The exoscope (EX) was developed to overcome these disadvantages. Herein, we compared OM and EX during mastoidectomy and found out the feasibility of the EX. STUDY DESIGN: Prospective randomized comparative study. SETTING: Tertiary academic medical center. PATIENTS: Patients who had mastoidectomy for chronic otitis media with or without cholesteatoma between January 2022 and April 2022. INTERVENTION: Canal wall-up mastoidectomy (CWUM) or canal wall-down mastoidectomy (CWDM) using OM or EX without endoscope. MAIN OUTCOME MEASURES: Operative setting time (the time between the end of general anesthesia and incision), operative time (from incision to suture), postoperative audiologic outcomes, perioperative complications, and the decision to switch from EX to OM. RESULTS: Of 24 patients who were diagnosed with chronic otitis media or cholesteatoma, 12 each were randomly assigned to the OM or EX group. The mean operation time was 175 ± 26.5 minutes and 172 ± 34.6 minutes in the EX and OM group, respectively, which was not significantly different ( p = 0.843). The procedures in the EX group were successfully completed using a three-dimensional (3D)-EX without conversion to OM. All surgeries were completed without any complications. The postoperative difference in the air and bone conduction was 11.2 and 12.4 dB in the EX and OM groups, respectively, which was not significantly different ( p = 0.551). CONCLUSIONS: EX is comparable to OM in terms of surgical time, complications, and audiologic outcomes following mastoidectomy. The EX system is a potential alternative to OM. However, further improvements are required to overcome some drawbacks (deterioration of image resolution at high magnification, requirement of an additional controller for refocusing).


Assuntos
Colesteatoma da Orelha Média , Otite Média , Humanos , Colesteatoma da Orelha Média/cirurgia , Doença Crônica , Processo Mastoide/cirurgia , Mastoidectomia/métodos , Otite Média/cirurgia , Estudos Prospectivos , Estudos Retrospectivos , Resultado do Tratamento
16.
Otolaryngol Head Neck Surg ; 170(6): 1555-1560, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38520201

RESUMO

OBJECTIVE: To develop a convolutional neural network-based computer vision model to recognize and track 2 mastoidectomy surgical instruments-the drill and the suction-irrigator-from intraoperative video recordings of mastoidectomies. STUDY DESIGN: Technological development and model validation. SETTING: Academic center. METHODS: Ten 1-minute videos of mastoidectomies done for cochlear implantation by varying levels of resident surgeons were collected. For each video, containing 900 frames, an open-access computer vision annotation tool was used to annotate the drill and suction-irrigator class images with bounding boxes. A mastoidectomy instrument tracking module, which extracts the center coordinates of bounding boxes, was developed using a feature pyramid network and layered with DETECTRON, an open-access faster-region-based convolutional neural network. Eight videos were used to train the model, and 2 videos were used for testing. Outcome measures included Intersection over Union (IoU) ratio, accuracy, and average precision. RESULTS: For an IoU of 0.5, the mean average precision for the drill was 99% and 86% for the suction-irrigator. The model proved capable of generating maps of drill and suction-irrigator stroke direction and distance for the entirety of each video. CONCLUSIONS: This computer vision model can identify and track the drill and suction-irrigator from videos of intraoperative mastoidectomies performed by residents with excellent precision. It can now be employed to retrospectively study objective mastoidectomy measures of expert and resident surgeons, such as drill and suction-irrigator stroke concentration, economy of motion, speed, and coordination, setting the stage for characterization of objective expectations for safe and efficient mastoidectomies.


Assuntos
Aprendizado Profundo , Mastoidectomia , Redes Neurais de Computação , Gravação em Vídeo , Humanos , Mastoidectomia/métodos , Implante Coclear/métodos , Processo Mastoide/cirurgia , Cirurgia Assistida por Computador/métodos
17.
Eur Arch Otorhinolaryngol ; 281(6): 3283-3287, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38530458

RESUMO

BACKGROUND: While mastoid obliteration techniques have received much attention in decreasing the disadvantages associated with the resultant mastoid cavity from canal wall down procedures, techniques for an anatomically normal looking ear canal reconstruction to increase the feasibility of hearing aid fitting are less commonly discussed as an alternative. METHODS: Our mastoidoplasty technique basically utilises an inferiorly based periosteal flap with or without temporalis muscles and fascia to obliterate the epitympanum and reconstruct the external auditory canal (EAC). Stay sutures are used to keep them in place. For larger cavities, demineralized bone matrix (DBM) is used to obliterate the mastoid cavity and support the neo-EAC. CONCLUSIONS: The concept of our mastoidoplasty potentially provides a very useful alternative in recreating a near normal ear canal anatomy avoiding cavity problems as well as facilitating hearing aid fitting with canal type hearing aids after canal wall down mastoidectomy.


Assuntos
Meato Acústico Externo , Processo Mastoide , Mastoidectomia , Retalhos Cirúrgicos , Humanos , Mastoidectomia/métodos , Meato Acústico Externo/cirurgia , Processo Mastoide/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade
18.
Otol Neurotol ; 45(5): 542-548, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38511274

RESUMO

OBJECTIVE: To compare recidivism rates, audiometric outcomes, and postoperative complication rates between soft-wall canal wall reconstruction (S-CWR) versus bony-wall CWR (B-CWR) with mastoid obliteration (MO) in patients with cholesteatoma. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary neurotologic referral center. PATIENTS: Ninety patients aged ≥18 years old who underwent CWR with MO, either S-CWR or B-CWR, for cholesteatoma with one surgeon from January 2011 to January 2022. Patients were followed postoperatively for at least 12 months with or without second-look ossiculoplasty. INTERVENTIONS: Tympanomastoidectomy with CWR (soft vs. bony material) and mastoid obliteration. MAIN OUTCOME MEASURES: Recidivism rates; conversion rate to CWD; pre- versus postoperative pure tone averages, speech reception thresholds, word recognition scores, and air-bone gaps; postoperative complication rates. RESULTS: Middle ear and mastoid cholesteatoma recidivism rates were not significantly different between B-CWR (17.3%) and S-CWR (18.4%, p = 0.71). There was no significant difference in pre- versus postoperative change in ABG (B-CWR, -2.1 dB; S-CWR, +1.6 dB; p = 0.91) nor in the proportion of postoperative ABGs <20 dB (B-CWR, 41.3%; S-CWR, 30.7%; p = 0.42) between B-CWR and S-CWR. Further, there were no significant differences in complication rates between B-CWR and S-CWR other than increased minor TM perforations/retractions in B-CWR (63% vs. 40%, p = 0.03). CONCLUSIONS: Analysis of recidivism rates, audiometric outcomes and postoperative complications between B-CWR with MO versus S-CWR with MO revealed no significant difference. Both approaches are as effective in eradicating cholesteatoma while preserving relatively normal EAC anatomy and hearing. Surgeon preference and technical skill level may guide the surgeon's choice in approach.


Assuntos
Colesteatoma da Orelha Média , Processo Mastoide , Mastoidectomia , Humanos , Masculino , Feminino , Estudos Retrospectivos , Pessoa de Meia-Idade , Colesteatoma da Orelha Média/cirurgia , Adulto , Processo Mastoide/cirurgia , Mastoidectomia/métodos , Resultado do Tratamento , Timpanoplastia/métodos , Complicações Pós-Operatórias/epidemiologia , Procedimentos de Cirurgia Plástica/métodos , Idoso , Meato Acústico Externo/cirurgia , Adulto Jovem , Audiometria de Tons Puros , Recidiva
20.
Eur Arch Otorhinolaryngol ; 280(8): 3897-3900, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37195344

RESUMO

PURPOSE: It is unusual to have communication from the external auditory canal (EAC) directly to the mastoid, totally sparing the tympanum. These patients need a different surgical approach, a modified canal wall-down procedure, to completely clear the disease but fully preserve the tympanum. We present one such exceptional case. CASE PRESENTATION: A 28-year-old lady presented with ear discharge for 1 year. Imaging confirmed the canal-mastoid fistula, but the entire tympanum was normal. We performed a modified-modified radical mastoidectomy. CONCLUSIONS: Canal-mastoid fistula is an infrequent entity and may be idiopathic. Despite being evident on clinical examination, imaging aids in assessing size and location of the defect. Although EAC reconstruction may be attempted, the majority require a canal wall-down procedure.


Assuntos
Colesteatoma da Orelha Média , Otopatias , Feminino , Humanos , Adulto , Mastoidectomia/métodos , Estudos Retrospectivos , Processo Mastoide/diagnóstico por imagem , Processo Mastoide/cirurgia , Orelha Média , Otopatias/cirurgia , Meato Acústico Externo/diagnóstico por imagem , Meato Acústico Externo/cirurgia , Colesteatoma da Orelha Média/diagnóstico por imagem , Colesteatoma da Orelha Média/cirurgia
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