Knee joint distraction in regular care for treatment of knee osteoarthritis: A comparison with clinical trial data.

OBJECTIVES: Knee joint distraction (KJD) has been evaluated as a joint-preserving treatment to postpone total knee arthroplasty in knee osteoarthritis patients in three clinical trials. Since 2014 the treatment is used in regular care in some hospitals, which might lead to a deviation from the original indication and decreased treatment outcome. In this study, baseline characteristics, complications and clinical benefit are compared between patients treated in regular care and in clinical trials. METHODS: In our hospital, 84 patients were treated in regular care for 6 weeks with KJD. Surgical details, complications, and range of motion were assessed from patient hospital charts. Patient-reported outcome measures were evaluated in regular care before and one year after treatment. Trial patients (n = 62) were treated and followed as described in literature. RESULTS: Patient characteristics were not significantly different between groups, except for distraction duration (regular care 45.3±4.3; clinical trials 48.1±8.1 days; p = 0.019). Pin tract infections were the most occurring complication (70% regular care; 66% clinical trials), but there was no significant difference in treatment complications between groups (p>0.1). The range of motion was recovered within a year after treatment for both groups. WOMAC questionnaires showed statistically and clinically significant improvement for both groups (both p<0.001 and >15 points in all subscales) and no significant differences between groups (all differences p>0.05). After one year, 70% of patients were responders (regular care 61%, trial 75%; p = 0.120). Neither regular care compared to clinical trial, nor any other characteristic could predict clinical response. CONCLUSIONS: KJD as joint-preserving treatment in clinical practice, to postpone arthroplasty for end-stage knee osteoarthritis patient below the age of 65, results in an outcome similar to that thus far demonstrated in clinical trials. Longer follow-up in regular care is needed to test whether also long-term results remain beneficial and comparable to trial data.

Simultaneous lateral column shortening along with differential distraction by Joshi's external stabilization system for rigid neglected clubfoot correction.

Correction of rigid clubfoot in an older child by gradual differential distraction using the Ilizarov's device or Joshi's external stabilization system (JESS) is a time-consuming procedure. We simultaneously combined the lateral column shortening by cuboid wedge resection along with the differential distraction by application of JESS fixator for the treatment of severe, rigid, neglected, or relapsed congenital talipes equinovarus (CTEV) foot deformity in 30 feet in 18 children with mean age of 5.3 years and mean follow-up of 27.6 months. The mean pretreatment Pirani score was 5.3 which improved to mean Pirani score after treatment of 1.4. Excellent results were obtained in 22 (71.33%) feet, good results in four (13.33%) feet, and poor results in four (13.33%) feet. The average period for distraction in our series was 6.3 weeks, and total average period of fixator in place was 11.2 weeks. To conclude, lateral column shortening with JESS application simultaneously gives early good to excellent short-term results, and the combination of techniques permits rapid correction of deformity, and thus reducing the time for which the fixator is in place and hence has better acceptance by the patient.

Distração osteogênica mediossagital da mandíbula: avaliação em modelos de estudo / Mandibular symphyseal distraction osteogenesis: dental casts evaluation

Introdução: a distração osteogênica mediossagital da mandíbula (DOMM) tem sido apresentada como tratamento para apinhamento inferior associado à atresia mandibular. Objetivo: avaliar, por meio de modelos de estudo, os efeitos da DOMM na arcada inferior de pacientes que utilizam aparelhos dentossuportados....Métodos: a amostra consistiu de 14 pacientes com idades variando de 13 a 19 anos, ao início do tratamento. Modelos de estudos foram obtidos de cada paciente ao início do tratamento (T1), três meses após a DOMM (T2) e no momento da remoção dos aparelhos fixos (T3). Os dados foram submetidos à Análise de Variância e teste complementar de Duncun. Resultados: todas as dimensões transversais aumentaram com a DOMM, o comprimento da arcada não sofreu alteração estatisticamente significativa, o perímetro da arcada aumentou e o índice de irregularidade diminuiu consideravelmente, refletindo a correção das cúspides do que as cervicais, indicando uma possível inclinação causada pelo uso de aparelho dontossuportado. Todas as medidas mostraram algum grau de recidiva, que variou de 2,8% a 8,84%. Conclusões: os achados dessa pesquisa permitem concluir que a DOMM é uma alternativa eficaz para o tratamento do apinhamento associado à deficiência transversal da mandíbula.

The trans-sutural distraction osteogenesis for 22 cases of craniosynostosis: a new, easy, safe, and efficient method in craniosynostosis surgery.

BACKGROUND: Distraction osteogenesis for the treatment of craniosynostosis is becoming more widely used as it is simple, there are less transfusions, and a decreased incidence of complications, although a secondary procedure for the removal of the distractors is necessary. However, to date all previous procedures have still been complicated. The authors present a novel trans-sutural distraction osteogenesis method (TSuDO) for the treatment of all types of craniosynostosis. METHODS: The TSuDO consisted of simple suturectomy of the pathologic suture followed by direct distraction of the suturectomy site only. Types of TSuDO conducted were sagittal TSuDO in 6 patients, coronal TSuDO in 5 patients, unilateral coronal TSuDO in 8 patients, lambdoid TSuDO in 2 patients, and metopic TSuDO in 1 patient (total = 22). Mean age was 9.3 ± 12.7 months. RESULTS: The mean operation time was 143.6 ± 50.2 min, and mean total transfusion volume of blood components was 131.1 ± 78.3 ml. Immediate correction of the abnormal head contour after distraction was observed in all patients, and no complications were encountered except for 1 patient whose distractor malfunctioned and 2 who showed prolonged discharges from the pin sites (controlled by antibiotics). CONCLUSION: TSuDO is a simple, effective, and safe method for the treatment of all types of craniosynostosis, and is especially effective for the correction of unilateral coronal craniosynostosis.

Distracción osteogénica segmentaria de maxilar superior con distractores intraorales / Segmentary osteogenic distraction of maxillary with intraoral distractors

La retrusión mediofacial, con oclusión invertida clase III de Angle, en hipoplasias maxilares secundarias es frecuente en adolescentes con fisuras labiopalatinas. Deformidades similares se ven en las disostosis craneofacilaes operadas en la infancia...Se presenta un nuevo modelo de DOG con osteotomías segmentarias y distractores intraorales fijos a los dientes (SOD), de fácil uso y retiro ambulatorio...Se describen las técnicas de SOD y los resultados obtenidos con tres años de experiencia en 15 pacientes con hipoplasias maxilares