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The article has been written for the occasion of 25 Anniversary of Gliwice Scientific Meetings (GSN). For this reason, I am going to present scientific contacts of the Institute of Oncology at Gliwice with the Institute of Human Genetics of the Polish Academy of Sciences at Poznan not only at conference occasions but also in regular research manner.
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Congressos como Assunto , Polônia , Humanos , Pesquisa Biomédica/organização & administraçãoRESUMO
Cancer Core Europe brings together the expertise, resources, and interests of seven leading cancer institutes committed to leveraging collective innovation and collaboration in precision oncology. Through targeted efforts addressing key medical challenges in cancer and partnerships with multiple stakeholders, the consortium seeks to advance cancer research and enhance equitable patient care.
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Oncologia , Neoplasias , Humanos , Europa (Continente) , Oncologia/organização & administração , Oncologia/métodos , Neoplasias/terapia , Pesquisa Biomédica/organização & administração , Medicina de Precisão/métodosRESUMO
BACKGROUND: Lack of diversity in the cancer research workforce persists, which the new requirement for all National Cancer Institute (NCI)-designated cancer centers to have a Plan to Enhance Diversity (PED) seeks to address. However, it is not well understood how different cancer centers are approaching the development and execution of these plans. Our objective was to assess how cancer centers are establishing and pursuing their PED. METHODS: We conducted a cross-sectional survey of members of the Cancer Center Diversity, Equity and Inclusion Network, which includes all NCI-designated cancer centers and several emerging centers. A total of 62 cancer centers (75% of those invited), including 58 NCI-designated cancer centers (81% of those with this designation), participated and completed a questionnaire that assessed PED leadership, major challenges, implementation strategies, and approach to evaluate PED progress. RESULTS: The most common PED challenge identified is recruiting diverse faculty (68% of centers), and the most common strategy currently used to address this is reviewing and revising faculty recruitment practices (67%). The most common approach centers are using to measure PED progress is shifts in demographics (68%), and data on the demographics of faculty, leadership, and trainees are available at 79%, 81%, and 75% of centers, respectively. CONCLUSIONS: Almost all centers have established a PED leadership structure, however, there is considerable variation in the approaches used to realize PED goals and in the resources provided to support PED work. Realizing opportunities to share and implement common best practices and exemplar programs has the potential to elevate the impact of PED efforts nationally.
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Institutos de Câncer , Diversidade Cultural , National Cancer Institute (U.S.) , Humanos , Estados Unidos , Estudos Transversais , Institutos de Câncer/organização & administração , Institutos de Câncer/estatística & dados numéricos , Inquéritos e Questionários , Liderança , Neoplasias/epidemiologia , Masculino , Feminino , Pesquisa Biomédica/organização & administraçãoRESUMO
The US National Cancer Act of 1971 designated the director of the National Cancer Institute as responsible for coordinating federal agencies and nonfederal organizations to make progress against cancer. As part of her role, the immediate past director of the National Cancer Institute (MMB) led the development of a National Cancer Plan that was formally released on April 3, 2023. The plan includes 8 aspirational goals "to achieve a society where every person with cancer lives a full and active life and to prevent most cancers so that few people need to face this diagnosis." Research findings provide a foundation for each goal, and research gaps are included in the strategies for meeting each goal. The President's Cancer Panel, also created by the National Cancer Act, conducted an initial assessment of progress toward the plan goals by hearing from 12 organizations at a virtual public meeting on September 7, 2023. The purpose of this commentary is to orient the scientific community to the plan and call attention to related knowledge gaps that could benefit from research.
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National Cancer Institute (U.S.) , Neoplasias , Humanos , Estados Unidos/epidemiologia , Neoplasias/epidemiologia , Neoplasias/prevenção & controle , Neoplasias/terapia , Pesquisa Biomédica/organização & administraçãoRESUMO
ABSTRACT: The National Trauma Research Action Plan project successfully engaged multidisciplinary experts to define opportunities to advance trauma research and has fulfilled the recommendations related to trauma research from the National Academies of Sciences, Engineering and Medicine report. These panels identified more than 4,800 gaps in our knowledge regarding injury prevention and the optimal care of injured patients and laid out a priority framework and tools to support researchers to advance this field. Trauma research funding agencies and researchers can use this executive summary and supporting manuscripts to strategically address and close the highest priority research gaps. Given that this is the most significant public health threat facing our children, young adults, and military service personnel, we must do better in prioritizing these research projects for funding and providing grant support to advance this work. Through the Coalition for National Trauma Research, the trauma community is committed to a coordinated, collaborative approach to address these critical knowledge gaps and ultimately reduce the burden of morbidity and mortality faced by our patients.
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Pesquisa Biomédica , Ferimentos e Lesões , Humanos , Ferimentos e Lesões/terapia , Estados Unidos , Pesquisa Biomédica/organização & administração , Traumatologia/organização & administraçãoRESUMO
Data commons have proven to be an indispensable avenue for advancing pediatric cancer research by serving as unified information technology platforms that, when coupled with data standards, facilitate data sharing. The Pediatric Cancer Data Commons, the flagship project of Data for the Common Good (D4CG), collaborates with disease-based consortia to facilitate development of clinical data standards, harmonization and pooling of clinical data from disparate sources, establishment of governance structure, and sharing of clinical data. In the interest of international collaboration, researchers developed the Hodgkin Lymphoma Data Collaboration and forged a relationship with the Pediatric Cancer Data Commons to establish a data commons for pediatric Hodgkin lymphoma. Herein, we describe the progress made in the formation of Hodgkin Lymphoma Data Collaboration and foundational goals to advance pediatric Hodgkin lymphoma research.
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Doença de Hodgkin , Doença de Hodgkin/terapia , Humanos , Criança , Disseminação de Informação , Pesquisa Biomédica/organização & administração , Bases de Dados FactuaisRESUMO
BACKGROUND: Musculoskeletal (MSK) injuries are one of the leading causes of disability worldwide. Despite improvements in trauma-related morbidity and mortality in high-income countries over recent years, outcomes following MSK injuries in low- and middle-income countries, such as South Africa (SA), have not. Despite governmental recognition that this is required, funding and research into this significant health burden are limited within SA. This study aims to identify research priorities within MSK trauma care using a consensus-based approach amongst MSK healthcare practitioners within SA. METHOD: Members from the Orthopaedic Research Collaboration in Africa (ORCA), based in SA, collaborated using a two round modified Delphi technique to form a consensus on research priorities within orthopaedic trauma care. Members involved in the process were orthopaedic healthcare practitioners within SA. RESULTS: Participants from the ORCA network, working within SA, scored research priorities across two Delphi rounds from low to high priority. We have published the overall top 10 research priorities for this Delphi process. Questions were focused on two broad groups-clinical effectiveness in trauma care and general trauma public health care. Both groups were represented by the top two priorities, with the highest ranked question regarding the overall impact of trauma in SA and the second regarding the clinical treatment of open fractures. CONCLUSION: This study has defined research priorities within orthopaedic trauma in South Africa. Our vision is that by establishing consensus on these research priorities, policy and research funding will be directed into these areas. This should ultimately improve musculoskeletal trauma care across South Africa and its significant health and socioeconomic impacts.
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Sistema Musculoesquelético , Ortopedia , Apoio à Pesquisa como Assunto , Pesquisa , Humanos , Consenso , Atenção à Saúde , Ortopedia/organização & administração , Ortopedia/normas , Pesquisa/economia , Pesquisa/organização & administração , África do Sul , Pesquisa Biomédica/economia , Pesquisa Biomédica/organização & administração , Sistema Musculoesquelético/lesões , Ferimentos e Lesões , Técnica Delphi , Fraturas Expostas , Apoio à Pesquisa como Assunto/economia , Apoio à Pesquisa como Assunto/organização & administraçãoAssuntos
Neoplasias , United States Government Agencies , Pesquisa Biomédica/economia , Pesquisa Biomédica/organização & administração , Equidade em Saúde , Humanos , Neoplasias/diagnóstico , Neoplasias/mortalidade , Neoplasias/prevenção & controle , Neoplasias/terapia , Estados Unidos , United States Government Agencies/economia , United States Government Agencies/legislação & jurisprudência , United States Government Agencies/organização & administraçãoRESUMO
The COVID-19 pandemic and subsequent lockdown had a substantial impact on normal research operations. Researchers needed to adapt their methods to engage at-home participants. One method is crowdsourcing, in which researchers use social media to recruit participants, gather data, and collect samples. We utilized this method to develop a diagnostic test for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). Participants were recruited via posts on popular social-media platforms, and enrolled via a website. Participants received and returned a mail kit containing bladder symptom surveys and a urine sample cup containing room-temperature preservative. Using this method, we collected 1254 IC/BPS and control samples in 3 months from all 50 United States. Our data demonstrate that crowdsourcing is a viable alternative to traditional research, with the ability to reach a broad patient population rapidly. Crowdsourcing is a powerful tool for at-home participation in research, particularly during the lockdown caused by the COVID-19 pandemic.
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Pesquisa Biomédica , COVID-19 , Crowdsourcing/métodos , Cistite Intersticial , Participação do Paciente , Urinálise , Pesquisa Biomédica/organização & administração , Pesquisa Biomédica/tendências , COVID-19/epidemiologia , COVID-19/prevenção & controle , Controle de Doenças Transmissíveis , Cistite Intersticial/diagnóstico , Cistite Intersticial/epidemiologia , Técnicas e Procedimentos Diagnósticos/tendências , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Participação do Paciente/métodos , Participação do Paciente/estatística & dados numéricos , Seleção de Pacientes , Kit de Reagentes para Diagnóstico/provisão & distribuição , Projetos de Pesquisa , SARS-CoV-2 , Mídias Sociais , Manejo de Espécimes/métodos , Estados Unidos/epidemiologia , Urinálise/instrumentação , Urinálise/métodosRESUMO
Providing medical care at the highest levels across various reproductive endocrinology and infertility settings necessitates seamless partnership among multiple people with diverse skill sets. In this introductory article for this month's Views and Reviews, the concept of teaming is presented, including the key concepts of collaboration, assembling the right team members, establishing goals, inspiring and empowering others, and encouraging new approaches to optimize outcomes. Following this introduction, thought leaders from diverse reproductive endocrinology and infertility spaces, including clinical, ambulatory surgery, laboratory, and research settings, present their experiences using teaming models to adapt team members' thinking, elevate the quality of scientific productivity, and achieve excellence in both patient care and laboratory and clinical outcomes.
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Endocrinologia/organização & administração , Equipe de Assistência ao Paciente/organização & administração , Medicina Reprodutiva/organização & administração , Procedimentos Cirúrgicos Ambulatórios , Pesquisa Biomédica/organização & administração , Eficiência Organizacional , Feminino , Humanos , Infertilidade/diagnóstico , Infertilidade/terapia , Comunicação Interdisciplinar , Laboratórios Clínicos/organização & administração , Masculino , Segurança do Paciente/normas , Gravidez , Garantia da Qualidade dos Cuidados de Saúde/organização & administraçãoRESUMO
The RadioTransNet programme launched under the auspices of French societies for radiation oncology (SFRO) and medical physics (SFPM) was approved by the French national cancer institute (INCa) in December 2018 and is dedicated to proposing a relevant national and transversal structure for preclinical research including translational research in radiation oncology with well-defined priority areas of research. Its activities, coordinated by a scientific committee that includes radiation oncologists, medical physicists, academic biologists, are structured around several main areas, i.e.: target volume definition, interaction of radiation with normal tissues, combined treatments and modern dose calculation approaches. Four work packages have been created in these areas and are associated with other objectives pertaining to fundamental radiobiology, early implementation of new drugs in a preclinical setting, contribution of imaging in this task, research in medical physics including transversal components such as medical oncology, radiology, nuclear medicine and also cost/efficiency evaluation. All these tasks will be included in a national network that uses the complementary expertise provided by partners involved in the scheme. Calls for proposals will be selected by the scientific council to be submitted to INCa and the various academic associations to obtain funding for the human and technical resources required to conduct under optimal conditions projects in preclinical and translational research in radiation-oncology.
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Pesquisa Biomédica/organização & administração , Neoplasias/radioterapia , Radioterapia (Especialidade) , Comitês Consultivos/organização & administração , Terapia Combinada/métodos , Congressos como Assunto/organização & administração , França , Humanos , Neoplasias/patologia , Órgãos em Risco/efeitos da radiação , Dosagem Radioterapêutica , Sociedades Médicas , Pesquisa Translacional Biomédica/organização & administração , Carga TumoralAssuntos
Atitude do Pessoal de Saúde , Empoderamento , Neoplasias de Cabeça e Pescoço , Defesa do Paciente , Participação do Paciente , Sociedades Médicas/organização & administração , Especialidades Cirúrgicas/organização & administração , Pesquisa Biomédica/organização & administração , Sobreviventes de Câncer , Neoplasias de Cabeça e Pescoço/diagnóstico , Neoplasias de Cabeça e Pescoço/mortalidade , Neoplasias de Cabeça e Pescoço/terapia , Humanos , Estados Unidos/epidemiologia , VozRESUMO
Research activities and scientific advance achieved in 2020 at the State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine¼ (NRCRM) concerning medical problems of the Chornobyl disaster, radiation medicine, radiobiology, radiation hygiene and epidemiology in collaboration with the WHO network of medical preparedness and assistance in radiation accidents are outlined in the annual report. The report presents the results of fundamental and applied research works of the study of radiation effects and health effects of the Chornobyl accident. The report also shows the results of scientific-organizational and health care work, staff training. The Scientific Council meeting of NAMS approved the NRCRM Annual Report.
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Pesquisa Biomédica/organização & administração , Pesquisa Biomédica/estatística & dados numéricos , Acidente Nuclear de Chernobyl , Lesões por Radiação/epidemiologia , Liberação Nociva de Radioativos/estatística & dados numéricos , Radiobiologia/organização & administração , Radiobiologia/estatística & dados numéricos , Academias e Institutos/organização & administração , Academias e Institutos/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ucrânia/epidemiologiaAssuntos
Pesquisa Biomédica/organização & administração , Oftalmopatias/prevenção & controle , National Eye Institute (U.S.)/organização & administração , Oftalmologia/organização & administração , Inovação Organizacional , Objetivos Organizacionais , Transtornos da Visão/prevenção & controle , Humanos , Técnicas de Planejamento , Avaliação de Programas e Projetos de Saúde , Estados UnidosAssuntos
Pesquisa Biomédica/organização & administração , Bolsas de Estudo/organização & administração , Equidade de Gênero/estatística & dados numéricos , Internato e Residência/organização & administração , Cirurgia Plástica/educação , Pesquisa Biomédica/economia , Pesquisa Biomédica/estatística & dados numéricos , Bases de Dados Factuais , Bolsas de Estudo/economia , Bolsas de Estudo/estatística & dados numéricos , Feminino , Humanos , Internato e Residência/economia , Internato e Residência/estatística & dados numéricos , Masculino , Cirurgia Plástica/economia , Inquéritos e Questionários/estatística & dados numéricosRESUMO
BACKGROUND: Coronavirus disease 2019 (COVID-19) was declared a pandemic by the WHO on 11 March 2020 and global surgical practice was compromised. This Commission aimed to document and reflect on the changes seen in the surgical environment during the pandemic, by reviewing colleagues' experiences and published evidence. METHODS: In late 2020, BJS contacted colleagues across the global surgical community and asked them to describe how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had affected their practice. In addition to this, the Commission undertook a literature review on the impact of COVID-19 on surgery and perioperative care. A thematic analysis was performed to identify the issues most frequently encountered by the correspondents, as well as the solutions and ideas suggested to address them. RESULTS: BJS received communications for this Commission from leading clinicians and academics across a variety of surgical specialties in every inhabited continent. The responses from all over the world provided insights into multiple facets of surgical practice from a governmental level to individual clinical practice and training. CONCLUSION: The COVID-19 pandemic has uncovered a variety of problems in healthcare systems, including negative impacts on surgical practice. Global surgical multidisciplinary teams are working collaboratively to address research questions about the future of surgery in the post-COVID-19 era. The COVID-19 pandemic is severely damaging surgical training. The establishment of a multidisciplinary ethics committee should be encouraged at all surgical oncology centres. Innovative leadership and collaboration is vital in the post-COVID-19 era.
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COVID-19/prevenção & controle , Assistência Perioperatória/tendências , Padrões de Prática Médica/tendências , Procedimentos Cirúrgicos Operatórios/tendências , Adulto , Pesquisa Biomédica/organização & administração , COVID-19/diagnóstico , COVID-19/economia , COVID-19/epidemiologia , Educação de Pós-Graduação em Medicina/métodos , Educação de Pós-Graduação em Medicina/tendências , Feminino , Saúde Global , Recursos em Saúde/provisão & distribuição , Acessibilidade aos Serviços de Saúde/tendências , Humanos , Controle de Infecções/economia , Controle de Infecções/métodos , Controle de Infecções/normas , Cooperação Internacional , Masculino , Pessoa de Meia-Idade , Pandemias , Assistência Perioperatória/educação , Assistência Perioperatória/métodos , Assistência Perioperatória/normas , Padrões de Prática Médica/normas , Cirurgiões/educação , Cirurgiões/psicologia , Cirurgiões/tendências , Procedimentos Cirúrgicos Operatórios/educação , Procedimentos Cirúrgicos Operatórios/métodos , Procedimentos Cirúrgicos Operatórios/normasRESUMO
INTRODUCTION: The incidence of cancer and its prevalence are increasing in Indonesia. It is crucial to ensure national cancer policies are evidence-based and promote research. While cancer research is being conducted across Indonesia, the extent and focus of research activities are not known, with no existing synthesis of the cancer research landscape. We seek to address this gap by characterising trends in the extent and types of cancer research conducted in Indonesia. METHODS: Scientometric study using descriptive analyses to determine annual growth patterns in publications across all cancer research literature from Indonesia. We developed a classification system for both research type and study design which was applied to all included publications. A visualisation software tool (VOSviewer) was used to explore the geographical distribution of research activity. The Wilcoxon rank-sum test was used to determine the influence of international collaboration on the impact factor of journals in which articles were published. RESULTS: We retrieved 1773 cancer-related articles published by Indonesia-affiliated authors from 1961 to 2020, with notable year-on-year increases in the annual total number of published articles since 2015. Most articles (84.0%) were published by authors affiliated with institutions on Java Island. The most commonly published article type was basic research and discovery science (28.8%), using a one-group analytical study design (28.8%). International collaboration was significantly correlated with a higher h-index of the journal in which research was published (P < .0001, r = .317). CONCLUSION: An increase in the number and range of topics explored in cancer-related publications over time was identified. The summary of the current corpus of cancer-related research for Indonesia can be used to direct the development of the national cancer control plan alongside informing the national cancer research strategy. Our novel and feasible scientometric approach can be used to direct future national and regional mapping of cancer research.