Building pathology capacity in sub-Saharan Africa to improve breast cancer diagnosis and treatment: training laboratory technicians in high-quality manual immunohistochemistry.

BACKGROUND: To address the need for a skilled workforce in breast cancer (BC) pathology in sub-Saharan Africa (SSA), we implemented an education program to train laboratory technicians in manual immunohistochemistry (IHC). METHODS: A quality improvement education project was developed. Interactive webinars were held every six months with didactics and presentations from African experts with experience in IHC. We conducted knowledge assessments and surveys on current practice, equipment, and human resources. A digital mentorship platform (DMP) was created for discussions, sharing SOPs, and networking. For one year (2022-2023), we followed developments in pathology capacity, practice changes, and educational needs. A paired t-test was used to calculate the significance of changes in knowledge immediately after the webinar and comfort level with topics 35 days after the webinar. RESULTS: Two hundred and sixty six participants from 10 SSA countries attended the first webinar, a series of six lectures on IHC theory, methods, and practice. Ninety-five participants from nine SSA countries provided a baseline assessment of pathology capacity and feedback. Mean knowledge increased by 17.4% immediately after the webinar (from 41.8% pre-webinar to 59.2% post, p = < 0.0001). Self-reported comfort level in topics 35 days after the webinar increased by 11.3%, but this was not statistically significant (mean 3.36 pre- to 3.74 post, p = 0.1). Over six months, recordings were accessed 412 times. After six months, the second webinar had 93 participants from eight SSA countries. Membership in the DMP increased from 64 to 172; recordings were viewed 412 times in six months; and 113 participants from nine SSA countries completed surveys. Among 74 respondents who perform IHC, 43.5% reported moderate or significant positive practice changes such as improved antigen retrieval techniques and optimization of preanalytical variables. Over half (52.7%, n = 39) reported the quality of slides had moderately or significantly improved. After one year, a third webinar had 98 participants from eight SSA countries. Thirty-eight completed surveys, DMP membership increased to 199, and 1 reported launching IHC in a lab in Nigeria. CONCLUSIONS: Our program 1) reached hundreds of participants and provided a baseline assessment of pathology capacity across nine SSA countries; 2) created a novel mechanism to build pathology capacity and assess progress with this cohort; and 3) improved practices and the preparation of slides for over half performing manual IHC. After one year, interest was sustained. Tracking impact on diagnosis and treatment of BC in the region is needed long-term.

The growing importance of cytogenetic biomonitoring studies in buccal mucosa of dental laboratory technicians.

The manuscript emphasizes some issues for the correct understanding of the recent paper accepted for publication in the Archives of Environmental & Occupational Health titled "Determination of cytogenetic abnormalities in buccal mucosa of dental laboratory technicians" by Yuksel and Yildirim.

Determination of cytogenetic abnormalities in buccal mucosa of dental laboratory technicians.

This study aims to investigate the toxic effects of metals, which dental technicians are exposed to, on the oral mucosa cells in dental prosthesis laboratories (DPL). To monitor cytotoxic effects, mutations of pyknosis, Karyolysis Karyorrhexis, binucleus, micronucleus, and broken-egg were evaluated. Experimental group comprised of a total of 30 volunteer DPL employees from various DPLs, and 30 teachers and office workers were volunteered to be a part of the control group. Age range of DPL employees and whether they consume alcohol or smoke cigarettes were also considered as sub-variables. Peripheral smear technique was applied by taking samples from the oral mucosa of the experimental group and the control group. Anomalies determined between technicians and control group were statistically significant (p < .05). However, our findings revealed that the sub-variables (ie, age range, alcohol, and smoking) did not significantly affect the anomalies.

Ciencias básicas en el proceso docente del técnico superior en Análisis Clínico y Medicina Transfusional / Basic sciences in the teaching process of the lab technician in Clinical Analysis and Transfusion Medicine

RESUMEN Fundamento: el diseño curricular debe partir de las exigencias sociales; este permite la determinación de las cualidades a alcanzar por el egresado y la estructura organizacional del proceso docente a nivel de carrera. Objetivo: valorar la importancia de las ciencias básicas en el plan del proceso docente del técnico superior en Análisis Clínico y Medicina Transfusional, por su influencia en la formación laboral del futuro egresado. Métodos: se realizó una investigación documental en el período comprendido entre septiembre y noviembre de 2019 en la Universidad de Ciencias Médicas de Camagüey. Se emplearon métodos teóricos: análisis-síntesis e inductivo-deductivo; y empíricos: el análisis documental a partir del cual se realizaron valoraciones cualitativa y cuantitativa del plan del proceso docente del técnico superior en Análisis Clínico y Medicina Transfusional. Resultados: en el plan del proceso docente de esta carrera no aparecen las asignaturas clasificadas por ciclos y se evidencia una disminución considerable del ciclo básico. Conclusiones: la valoración realizada evidencia que falta precisión del papel que juega cada ciclo de las asignaturas en el plan del proceso docente, lo que influye negativamente en su cientificidad y se demuestra que tiene una elevada carga laboral, ya que el estudiante desde sus primeros años se encuentra vinculado al trabajo diario en el servicio asistencial en el que adquiere habilidades propias de la profesión.

ABSTRACT Background: curricular design must start from social demands; this allows the determination of the qualities to be achieved by the graduate and the organizational structure of the teaching process at degree level. Objective: to assess the importance of basic sciences in the plan of the teaching process of the lab technician in Clinical Analysis and Transfusion Medicine, due to its influence on the job training of future graduates. Methods: a documentary research was carried out in the period from September to November 2019 at Camagüey University of Medical Sciences. Theoretical methods were used: analysis-synthesis and inductive-deductive; and empirical ones: the documentary analysis from which qualitative and quantitative evaluations were made of the plan of the teaching process of the lab technician in Clinical Analysis and Transfusion Medicine. Results: in the plan of the teaching process of this degree, the subjects classified by cycles do not appear and there is a considerable decrease in the basic cycle. Conclusions: the assessment carried out shows that there is a lack of precision in the role that each cycle of the subjects play in the plan of the teaching process, which negatively influences its scientific approach and shows that it has a high workload, since the student from its early years is linked to daily work in the healthcare service in which it acquires distinctive skills of the profession.

Cumplimiento de las normas de bioseguridad en laboratorios de la Universidad Técnica de Machala / Fulfillment of the biosafety norms in laboratories of the Universidad Técnica de Machala

Establecer el cumplimiento de las normas de bioseguridad por parte de los profesionales que laboran en los laboratorios de la Facultad de Ciencias Químicas y de la Salud de la Universidad Técnica de Machala. Materiales y Métodos: La presente investigación es de tipo descriptiva, con enfoque cuantitativo. La modalidad de la investigación es de campo. La población estuvo constituida por 100 estudiantes que usan los diferentes laboratorios de la Facultad de Ciencias Químicas y de la Salud de la Universidad Técnica de Machala. Resultados: El 59% de la población contestó que sí, ha recibido capacitación acerca de las normas de bioseguridad en la institución y el 41% respondieron que no. El 73% de los estudiantes cumplen con las medidas de bioseguridad en el laboratorio. Se realiza el lavado de manos, con un equivalente a un 39% para Después de tener contacto con cualquier tipo de materiales, muestras biológicas, productos sólidos, sustancias o reactivos. Sobre si se cuentan con recipientes de descarte para elementos contaminados, y están debidamente identificados el cual corresponde a un 46,9%. A la pregunta sobre qué materiales se deposita en los guardianes dando un equivalente de 43% para las Jeringuillas, bisturí, sin embargo, las Lancetas, agujas. Conclusiones: Se pudo determinar que la gran parte de la población estudiada si cumplen con las normas de bioseguridad(AU)

To establish compliance with Biosafety standards by professionals working in the laboratories of the Faculty of Chemistry and Health Sciences of the Technical University of Machala. Materials and Methods: This is a descriptive research with a quantitative approach. The modality of the research is field research. The population consisted of 100 students who use the different laboratories of the Faculty of Chemistry and Health Sciences of the Technical University of Machala. Results: 59% of the population answered that they had received training on Biosafety norms in the institution and 41% answered that they had not. Seventy-three percent of the students comply with Biosafety measures in the laboratory. Hand washing is performed, with an equivalent of 39% for after having contact with any type of materials, biological samples, solid products, substances or reagents. Regarding whether there are disposal containers for contaminated items, and whether they are properly identified, this corresponds to 46.9%. To the question about what materials are deposited in the guards giving an equivalent of 43% for syringes, scapel powever, Lancets, needles. Conclusions: It could be determined that the great part of the population studied if they comply with Biosafety standards

Research Funding, Income, and Career Satisfaction Among Clinician-Scientists in Ophthalmology in the United States.

PURPOSE: The purpose of this study was to characterize clinician-scientists in ophthalmology and identify factors associated with successful research funding, income, and career satisfaction. DESIGN: Cross-sectional study. METHODS: A survey was conducted of clinician-scientists in ophthalmology at US academic institutions between April 17, 2019, and May 19, 2019. Collected information including 1) demographic data; 2) amount, type, and source of startup funding; first extramural grant; and first R01-equivalent independent grant; 3) starting and current salaries; and 4) Likert-scale measurements of career satisfaction were analyzed using multivariate regression. RESULTS: Ninety-eight clinician-scientists in ophthalmology were surveyed across different ages (mean: 48 ± 11 years), research categories, institutional types, geographic regions, and academic ranks. Median startup funding ranged from $50-99k, and median starting salaries ranged from $150-199k. A majority of investigators (67%) received their first extramural award from the National Eye Institute, mainly through K-award mechanisms (82%). The median time to receiving their first independent grant was 8 years, mainly through an R01 award (70%). Greater institutional startup support (P = .027) and earlier extramural grant success (P = .022) were associated with earlier independent funding. Male investigators (P = .001) and MD degreed participants (P = .008) were associated with higher current salaries but not starting salaries. Overall career satisfaction increased with career duration (P = .011) but not with earlier independent funding (P = .746) or higher income (P = .300). CONCLUSIONS: Success in research funding by clinician-scientists in ophthalmology may be linked to institutional support and earlier acquisition of extramural grants but does not impact academic salaries. Nevertheless, career satisfaction among clinician-scientists improves with time, which is not necessarily influenced by research or financial success.

Investigation of morphological abnormalities in red blood cells among dental laboratory technicians.

A variety of materials are used in dental prosthesis laboratories (DPL), especially metal alloys and methyl methacrylate (MMA)-based monomers and polymers. These metal alloys contain elements such as cobalt, chromium, nickel, molybdenum, lead, and mercury that can have toxic effects on human health when excessive amounts of exposure occur. This study aims to investigate the cytotoxic effects of occupational exposure due to dental prosthesis manufacturing operations on erythrocyte cells. Thirty DPL workers were compared with the 30 control group and the questionnaire forms were applied including the symptoms due to their occupational exposure. Blood was taken from the experimental group and the control group into tubes with EDTA, and the erythrocyte morphologies were examined by the peripheral smear technique. Morphological anomalies determined from the experimental group and the control group are statistically significant (p < .005, p < .01). On the other hand, it was revealed that the sub-variables, namely age range, alcohol, and smoking, did not significantly affect the anomalies. With these results, it was concluded that DPL employees should strictly comply with occupational health precautions.

Optimizing cytological specimens of EUS-FNA of solid pancreatic lesions: A pilot study to the effect of a smear preparation training for endoscopy personnel on sample quality and accuracy.

BACKGROUND: In the absence of rapid on-side pathological evaluation, endoscopy staff generally "smears" endoscopic ultrasound guided fine needle aspiration (EUS-FNA) specimens on a glass slide. As this technique is vulnerable to preparation artifacts, we assessed if its quality could be improved through a smear-preparation-training for endoscopy staff. METHODS: In this prospective pilot study, 10 endosonographers and 12 endoscopy nurses from seven regional EUS-centers in the Netherlands were invited to participate in a EUS-FNA smear-preparation-training. Subsequently, post training slides derived from solid pancreatic lesions were compared to pre-training "control" slides. Primary outcome was to assess if the training positively affects smear quality and, consequently, diagnostic accuracy of EUS-FNA of solid pancreatic lesions. RESULTS: Participants collected and prepared 71 cases, mostly pancreatic head lesions (48%). Sixty-eight controls were selected from the pretraining period. The presence of artifacts was comparable for smears performed before and after training (76% vs 82%, P = .36). Likewise, smear cellularity (≥50% target cells) before and after training did not differ (44% (30/68) vs 49% (35/71), P = .48). Similar, no difference in diagnostic accuracy for malignancy was detected (P = .10). CONCLUSION: In this pilot EUS-FNA smear-preparation-training for endoscopy personnel, smear quality and diagnostic accuracy were not improved after the training. Based on these results, we plan to further study other training programs and possibilities.

Targeted education as a method for reinforcing Paris System criteria and reducing urine cytology atypia rates.

INTRODUCTION: The Paris System for Urine Cytology (TPS) provides well-defined diagnostic criteria for the category of atypical urothelial cells (AUC). The current study compares the rate of AUC diagnoses at a large academic medical center before and after an educational intervention (EI) by a urine cytology expert. MATERIALS AND METHODS: An expert in TPS delivered an educational intervention consisting of an interactive microscope session and a didactic session that focused on the AUC diagnostic category. The number of urine cytology cases, the AUC rate, and the false-negative percentage were calculated before and after the EI, using the electronic medical records and cytologic-histologic correlation records. RESULTS: A total of 4026 urine cytology cases were signed out in the 25 months prior to the educational intervention and 1585 cases were signed out in the 10 months after the intervention. EI had a significant impact on diagnostic categorization, including a reduction in AUC (19.6% versus 12.5%) and suspicious for high-grade urothelial carcinoma (3.9% versus 3.1%) diagnoses. The cytotechnologists also placed fewer cases into the AUC category during primary screening (27.6% versus 23.0%). Although a higher percentage of cases was reported as negative for high-grade urothelial carcinoma, the false-negative rate did not significantly change after the intervention (1.8% versus 2.0% of negative cases, P = 0.65). CONCLUSIONS: Focused educational sessions for pathologists and cytotechnologists on the diagnostic criteria for AUC as defined by TPS can significantly reduce the rate of atypical diagnoses without a significant increase in the rate of false negatives.

From Pharmacology Research, to Pharmacology Regulation, and Back-as Inspired by the Teachings of Dr. Gavril Pasternak.

Dr. Gavril Pasternak, M.D., Ph.D. was an inspiration to many of his students, including myself. It was with great sadness that I learned about the passing of Dr. Gavril Pasternak in February 2019 after his brief battle with pancreatic cancer. I worked with Dr. Pasternak while I was an undergraduate chemistry student and as one of his technicians, collaborating with Dr. Charles Inturrisi and Dr. Eliot F. Hahn on opiate agonists and antagonists for opioid receptor subtypes. Dr. Pasternak inspired me and set me on the road to a career in pharmacology and encouraged me to pursue the fruitful paradigm of moving therapeutics from bench to bedside.

Perspectives on Geoff Burnstock as researcher, teacher and friend.

Geoffrey Burnstock, one of the most talented and brilliant scientists of his generation, was born on the 10th of May 1929 in London and died on the 2ndof June 2020, aged 91, in Melbourne (Australia). Geoffrey Burnstock started his research studies with an interest in the nerves controlling the guts of guinea pigs, and discovered a completely unexpected and ubiquitous signalling system mediated via extracellular nucleotides (the "purinergic theory"), which revolutionized our understanding of how cells communicate between each other. He made the highly controversial discovery that ATP (adenosine triphosphate), a molecule well known to biochemists for its role as a source of energy inside cells, could also transmit signals between them. Initially, his somewhat heretical theory, that did not fit conventional views, found considerable resistance in the scientific community. However, he continued to accumulate evidence in favor of his hypothesis, extending it to a variety of organs and systems and demonstrating a role for purinergic signaling in the cardiovascular, respiratory and nervous systems, and in the pathophysiology of pain, blood clotting, cell proliferation and differentiation, and immunity. For his entire life, he struggled to attract scientists to this new field and, finally, in the early 1990s, did evidence emerge that convinced the doubters, due to new molecular biology techniques making it possible to isolate and identify the cell surface receptors for ATP and its breakdown product, adenosine. His death clearly impacted a huge number of scientists who have lost their pioneering leader. In this Review, I will not talk of the many discoveries made by Professor Burnstock, nor of his enormous scientific contributions to the field and of the incredible number of prizes and public recognitions that he has received after his theory was accepted worldwide. Instead, I will share some personal memories on him as a teacher and scientist, and, most of all, as a loyal and reliable friend. Geoff was an extraordinary human being, always eager to collaborate and share data, never jealous of his findings and capable of learning even from young people. He was known for his enthusiasm, empathy and ability to motivate young scientists. I was lucky to meet him when I was still very young, and the collaboration and friendship that we established and maintained across the years has profoundly conditioned my professional and personal life. For me, Geoff was what in Italy we call a "Maestro", one of those leading figures who are fundamental not only for mentoring an individual's career but also their growth as a scientist and as a human being.

How the COVID-19 Pandemic Impacted Oncological Molecular Diagnosis: A Picture from a National Reference Center for Molecular Pathology.

INTRODUCTION: The Portuguese healthcare system had to adapt at short notice to the COVID-19 pandemic. We implemented workflow changes to our molecular pathology laboratory, a national reference center, to maximize safety and productivity. We assess the impact this situation had on our caseload and what conclusions can be drawn about the wider impact of the pandemic in oncological therapy in Portugal. Material and Methods. We reviewed our database for all oncological molecular tests requested between March and April of 2019 and 2020. For each case, we recorded age, sex, region of the country, requesting institution, sample type, testing method, and turnaround time (TAT). A comparison between years was made. RESULTS: The total number of tests decreased from 421 in 2019 to 319 in 2020 (p = 0.0027). The greatest reduction was in clinical trial-related cases. Routine cases were similar between years (267 vs. 256). TAT was higher in 2019 (mean 15 days vs. 12.3 days; p = 0.0003). Medium- to large-sized public hospitals in the north of the country were mostly responsible for the reduction in cases (p = 0.0153). CONCLUSIONS: Case reduction was observed at hospitals that have mostly been involved in the treatment of COVID-19 and in the north of the country, the region worst-hit by the pandemic. Similar to other studies, our TAT decreased, even with a similar number of routine cases. Thus, we conclude that it is possible to successfully adapt the workflow of a molecular pathology laboratory to new safety standards without losing efficiency.

Implementation of p16/Ki67 dual stain cytology in a Danish routine screening laboratory: Importance of adequate training and experience.

BACKGROUND: Immunocytochemical staining with p16/Ki67 has been suggested as a promising triage biomarker in cervical cancer screening. As dual staining is a subjective method, proper training may be required to ensure safe implementation in routine laboratories and reduce risk of misclassification. We determined concordance between novice evaluators and an expert, stratified by number of slides reviewed at three reading points. METHODS: The study was conducted at the Department of Pathology, Randers, Denmark. Women were eligible if they were aged ≥45, had been enrolled in one of two ongoing clinical studies, and had a dual stain slide available. Dual staining was performed using the CINtec plus assay. Slides were randomly selected from three reading points at which novice evaluators had reviewed <30, ~300, and ≥500 dual stain slides respectively. Level of concordance was estimated using Cohen's Kappa, κ. RESULTS: Of 600 eligible slides, 50 slides were selected for review as recommended by the manufacturer. Median age was 68 years (range: 58-74). Overall concordance was good (κ = 0.68, 95% confidence interval [CI]: 0.60-0.76), with an overall agreement of 84% (95% CI: 70.9%-92.8%). Concordance improved with increasing number of slides reviewed at a given reading point, from a moderate concordance (κ = 0.47, 95% CI: 0.05-0.90) after reviewing <30 slides to a good concordance (κ = 0.66, 95% CI: 0.20-0.88) and a very good concordance (κ = 0.88, 95% CI: 0.66-1.00) after reviewing ~300 and ≥500 slides, respectively. CONCLUSIONS: When interpreting dual stain slides from older women, concordance increased slightly as novice evaluators received more training and experience. Although further evaluation is warranted, these findings indicate that a significant amount of training and experience of novice evaluators may be needed to ensure accurate dual stain interpretation in this age group. Future studies should accurately describe training and experience of evaluators to enable a better comparison of concordance and diagnostic accuracy across studies. TRIAL REGISTRATION: NCT04114968 and NCT04298957.

Occupational exposure to Brucella spp.: A systematic review and meta-analysis.

Brucellosis is a neglected zoonotic disease of remarkable importance worldwide. The focus of this systematic review was to investigate occupational brucellosis and to identify the main infection risks for each group exposed to the pathogen. Seven databases were used to identify papers related to occupational brucellosis: CABI, Cochrane, Pubmed, Scielo, Science Direct, Scopus and Web of Science. The search resulted in 6123 studies, of which 63 were selected using the quality assessment tools guided from National Institutes of Health (NIH) and Case Report Guidelines (CARE). Five different job-related groups were considered greatly exposed to the disease: rural workers, abattoir workers, veterinarians and veterinary assistants, laboratory workers and hunters. The main risk factors and exposure sources involved in the occupational infection observed from the analysis of the articles were direct contact with animal fluids, failure to comply with the use of personal protective equipment, accidental exposure to live attenuated anti-brucellosis vaccines and non-compliance with biosafety standards. Brucella species frequently isolated from job-related infection were Brucella melitensis, Brucella abortus, Brucella suis and Brucella canis. In addition, a meta-analysis was performed using the case-control studies and demonstrated that animal breeders, laboratory workers and abattoir workers have 3.47 [95% confidence interval (CI); 1.47-8.19] times more chance to become infected with Brucella spp. than others individuals that have no contact with the possible sources of infection. This systematic review improved the understanding of the epidemiology of brucellosis as an occupational disease. Rural workers, abattoir workers, veterinarians, laboratory workers and hunters were the groups more exposed to occupational Brucella spp. infection. Moreover, it was observed that the lack of knowledge about brucellosis among frequently exposed professionals, in addition to some behaviors, such as negligence in the use of individual and collective protective measures, increases the probability of infection.

Importância do ensino de biossegurança na formação de técnicos em enfermagem: relato de experiência / Importance of biosecurity teaching in the training of nursing technicians: experience report / Importancia de la enseñanza de bioseguridad en entrenamiento técnico de enfermería: informe de experiencia

Introducción: Los cursos que capacitan a profesionales de la salud requieren que los estudiantes puedan correlacionar la teoría con la práctica, con el objetivo de minimizar los riesgos inherentes a la práctica profesional. Por lo tanto, la enseñanza de la bioseguridad en estos cursos es esencial para la formación de estos profesionales. Objetivo: Informar la pasantía de una clase del curso de Técnico en Enfermería que aborda la importancia de enseñar y adoptar buenas prácticas de bioseguridad en el laboratorio de enfermería. Metodología: Este es un informe de experiencia de un maestro del curso de Técnico de Enfermería de un Centro Territorial para la Educación Profesional (CETEP), basado en clases prácticas de procedimientos de enfermería que se llevan a cabo en el propio laboratorio de CETEP, que comenzó el día. 17 de mayo de 2018 y finalizó el 18 de junio del mismo año, totalizando 60 horas. Resultados y Discusión: Durante la pasantía, las actividades fueron abordadas y realizadas por el equipo de enfermería, tales como: signos vitales y medición de glucosa en sangre capilar; vendaje, venopunción periférica; administración de drogas, etc., utilizando medidas de bioseguridad para la prevención de accidentes. Conclusión: El estudio permitió verificar la importancia de la enseñanza de la bioseguridad en los cursos de Técnico de Enfermería, demostrando que la capacitación del estudiante de bioseguridad minimiza los riesgos y promueve una práctica más segura durante el proceso de enseñanza-aprendizaje, así como en la práctica profesional.

Introduction: The courses aimed at the formation of professionals who will work in the health areas increasingly require the student to be able to correlate theory with practice, aiming at minimizing the risks inherent in professional practice. Thus, the teaching of biosafety for health courses is essential for training health professionals, especially those who are part of the nursing team, since it is this class that is in constant contact with the patient performing complex actions. Objective: To report the internship of a class of the Nursing Technician course addressing the importance of teaching and adopting good biosafety practices in the nursing laboratory. Methodology: This is an experience report by a teacher of the Nursing Technician course of a Territorial Center for Professional Education (CETEP), based on practical classes of nursing procedures held in CETEP's own laboratory, which began on the day May 17, 2018 and ended June 18 of the same year, totaling 60 hours. Results and Discussion: During the internship, activities were taught and performed by the nursing team, such as: vital signs and capillary blood glucose measurement; dressing, peripheral venipuncture; drug administration etc, using biosecurity measures for accident prevention. Conclusion: The study made it possible to verify the importance of biosafety teaching in Nursing Technician courses, showing that the biosafety student's training minimizes the risks and promotes a safer practice during the teaching-learning process, as well as in the professional practice.

Introdução: Os cursos que formam profissionais de saúde exigem que o discente consiga correlacionar a teoria com a prática, visando à minimização dos riscos inerentes ao exercício profissional. Deste modo, o ensino da biossegurança nesses cursos é imprescindível para formação desses profissionais. Objetivo: relatar o estágio de uma turma do curso Técnico em Enfermagem abordando a importância de ensinar e adotar boas práticas de biossegurança no laboratório de enfermagem. Metodologia: Trata-se de um relato de experiência vivenciado por uma docente do curso Técnico em Enfermagem de um Centro Territorial de Educação Profissional (CETEP), oportunizada a partir das aulas práticas dos procedimentos de enfermagem realizadas no laboratório do próprio CETEP, iniciadas no dia 17 de maio do ano de 2018 e finalizadas no dia 18 de junho do mesmo ano, totalizando 60 horas. Resultados e Discussão: Durante a realização do estágio foram abordadas e executadas atividades que são de responsabilidade da equipe de enfermagem, tais como: aferição de sinais de vitais e glicemia capilar; curativo, punção venosa periférica; administração de medicamentos etc., utilizando medidas de biossegurança para a prevenção de acidentes. Conclusão: O estudo possibilitou verificara importância do ensino da biossegurança nos cursos de Técnico em Enfermagem, evidenciando que a capacitação do discente em biossegurança minimiza os riscos e promove uma prática mais segura tanto durante o processo de ensino-aprendizagem, quanto no exercício profissional.

British Journal of Biomedical Science in 2019. What have we learned?

In 2019 the British Journal of Biomedical Science published 40 articles in the various disciplines that comprise biomedical science. These were one review, 22 original articles and 17 'In Brief' short reports. Of those citing original data, the majority were in cellular pathology (14 papers), clinical chemistry (9 papers), and microbiology (6 papers: 4 in bacteriology and 2 in virology). There were 3 papers in haematology and 2 in andrology, whilst 5 papers crossed traditional discipline boundaries (such as the molecular genetics of IL6, liver function tests, and hepatocellular carcinoma). Over two-thirds of papers used techniques in molecular genetics. The present report will summarise key aspects of these publications that are of greatest relevance to laboratory scientists.