Now we are 30: 10 more years of MASCC.

This paper chronicles the third decade of MASCC from 2010. There was a generational change in this decade, building on the solid foundation of the founders. It included the first female President, and a new Executive Director with a background in strategy and business development and operations as applied to healthcare. The headquarters moved from Copenhagen to Toronto. The first meeting to be held outside of Europe or North America was held in Adelaide, Australia, and the membership in the Asia Pacific region expanded. A program of international affiliates saw national supportive care organisations formally link with MASCC. In cancer supportive care, there was a raft of new toxicities to manage as immunotherapies were added to conventional cytotoxic treatment. There was also a greater emphasis on the psychosocial needs of patients and families. New MASCC groups were formed to respond to this evolution in cancer management. The MASCC journal, Supportive Care in Cancer, continued to grow in impact, and MASCC published two editions of a textbook of supportive care and survivorship. The decade ended with the challenge of the COVID-19 pandemic, but that served to highlight the importance of good supportive care to patients with cancer.

Pioneers in Modern Craniofacial Surgery: Assessing the Academic Impact of Drs. Joseph Gruss and Paul Manson.

BACKGROUND: The authors conducted this study to assess the impact that Drs. Joseph Gruss and Paul Manson have had on craniofacial surgery through their individual contributions and through their trainees. METHODS: This was a retrospective analysis of fellows trained by either Dr. Gruss or Dr. Manson. Demographic and bibliometric measures were recorded for each fellow. Demographic factors included years since completion of fellowship training, current practice of craniomaxillofacial surgery, academic practice, and academic leadership roles. Bibliometric measures included number of publications, number of citations, and h-index. To adjust for scholarly activity before fellowship training, only contributions published after fellowship training were included. RESULTS: Over a 39-year period, a total of 86 surgeons completed fellowship training with either of the two principal surgeons. The mean time since completion of training was 18.7 ± 11.4 years. Seventy-nine percent of surgeons had active practices in craniomaxillofacial surgery; 54 percent had academic practices. The mean number of publications was 26.4 ± 69.3, the mean number of citations was 582 ± 2406, and the average h-index was 6.7 ± 10.6. Among academic surgeons, the average h-index was 10.7 ± 13.1, 89 percent practiced in North America, 89 percent had active practices in craniomaxillofacial surgery, and nearly 50 percent had achieved a leadership role. CONCLUSIONS: Modern craniofacial reconstruction has evolved from principles used in trauma and correction of congenital differences. The extensive impact that Drs. Paul Manson and Joseph Gruss have had on the field, and plastic surgery at large, is evident through their primary contributions and the immense impact their trainees have had on the field.

Homeopatia, medicina alternativa: entre contracultura, Nova Era e oficialização (Brasil, década de 1970) / Homeopathy, alternative medicine: between counterculture, the New Era, and formalization (Brazil, 1970s)

Resumo O artigo analisa como a homeopatia foi veiculada ao público leigo no Brasil da década de 1970, período importante no processo de legitimação desse conhecimento como especialidade médica, o que ocorre em 1980. As fontes analisadas - compostas de artigos que circulavam no Jornal do Brasil e de livros destinados ao público leigo - permitem distinguir diferentes interlocutores que possuíam expectativas diversas diante da homeopatia, revelando um universo heterogêneo de compreensões e utilizações dessa medicina. Ao mesmo tempo, as fontes estabelecem um universo de representações envolvidas na construção da homeopatia como medicina alternativa, em que é perceptível sua relação com os movimentos de contracultura e Nova Era na formação de um "público consumidor de homeopatia".

Abstract The objective of this text is to analyze how homeopathy was conveyed to the lay public in Brazil during the 1970s, an important period in the process of legitimizing this practice as a medical specialty, which occurred in 1980. The sources analyzed (composed of articles that circulated in the Jornal do Brasil and books intended for the lay public) allow the reader to distinguish different interlocutors with various expectations of homeopathy, revealing a heterogeneous universe of understandings and uses for this medical system. At the same time, the sources establish a universe of representations present in the construction of homeopathy as alternative medicine, which is noticeable in its relationship with the counterculture movements and New Era in forming a "consuming public" for homeopathy.

Thirty years of Tunisian publication of «case reports¼ in General Surgery (1989-2018).

OBJECTIVE: To describe the bibliometric profile of Tunisian "case report" publications in general surgery over the last thirty years (1989-2018). METHODS: This is a descriptive bibliometric study on "case reports", general surgery, Tunisian affiliation, indexed in the Medline database, between January 1, 1989 and December 31, 2018. The themes of Search articles were defined by referring to their major keywords used for their indexing. RESULTS: During 30 years of study, Medline indexed 188 papers in "General Surgery" type "case reports", signed by 80 authors in first position and 71 authors in last position, belonging to ten academic specialties and 19 professional affiliations. These papers were published by 60 journals, including the Ugandan magazine "Pan African Medical Journal", which published 23% of these "case reports" alone. The number of major indexing keywords was 299 words, mainly "Echinococcosis", "Pancreatic Cancers" and "Echinococcosis of the liver", together accounting for 18.1% of articles. CONCLUSION: The plethora of "case reports" in Tunisian general surgery publications over the last three decades was accompanied by a preferential edition in the journal "Pan Afr Med J" and a thematic focus on hydatid cysts and cancers pancreatic. Hence the importance of strengthening the capacity of Tunisian surgeons in research methodology and scientific medical writing.

Bibliometrics of Tunisian publications on respiratory tract diseases from 2010 to 2014.

AIM: To describe the bibliometric characteristics of Tunisian publications on respiratory tract diseases, during the quinquennium 2010-2014. METHODS: This is a descriptive bibliometric study of respiratory medicine publications, indexed in "Medline", based on their MSDSs. All included articles were written by Tunisian researchers regardless of their position in the list of co-authors. The topics of the publications were explored through their "major" and "generic" keywords. RESULTS: A total of 340 publications was captured in Medline. These articles were co- authored by 218 authors in first position and 163 in last position. They were signed by pulmonologists, in first and last position respectively in 21.5% and 22.4% of articles. The A. Mami Hospital was the major affiliation of the first authors in 19.7% of the publications. These articles were published by 138 journals including "La Tunisie Medicale" in 11.8% of cases. They were "case reports" and written in English respectively in 44.4% and 54.1% of cases. Among 639 major keywords indexing, three were dominant: «Lung Neoplasms¼ (Tumeurs du poumon), «Chronic Obstructive Pulmonary Disease¼ (Broncho-pneumopathie chronique obstructive) and «Tuberculosis, Pulmonary¼ (Tuberculose pulmonaire), in 13.5%, 10.3% and 7.4% of articles respectively. CONCLUSION: Tunisian research on respiratory tract diseases has been thematically concordant with the public health needs. However, it has often been of low-level evidence and published in low-impact factor journals.

The top 100: A review of the most cited articles in Surgery. / Los top 100. Revisión de los artículos más citados en cirugía.

INTRODUCTION: We performed a study of the top 100 most cited articles in the five general surgery journals with the highest impact according to Journal Citation Report. METHODS: We selected the five journals with the highest impact in 2015: Annals of Surgery, British Journal of Surgery, JAMA Surgery, Surgery, and Journal of the American College of Surgeons. In January 2017, using the Web of Science application, we performed a search of all articles published by these journals and identified the 100 most cited articles (top 100). We evaluated the number of citations, year of publication, type of article, country and hospital of the article, area of interest and number of authors. RESULTS: The median number of citations per top 100 paper was 490. Twenty percent of the top 100 papers have been published since 2000. Overall, 70% are original papers, 8% randomized control trials, 11% reviews, 1% meta-analyses and 11% other subtypes. There are 13% proceedings papers. Sixty-one percent are from the US. The most frequently discussed topic is hepato-pancreato-biliary surgery (33%). CONCLUSIONS: The top 100 most cited articles tend to be original articles describing studies carried out in the US, reporting significant surgical breakthroughs. Hepato-pancreato-biliary surgery is the most common subject area. Annals of Surgery had twice as many citations as the other journals studied. The archetypal article of the Top15 most cited is an original paper published in the twentieth century, with an average of 2000 citations.

Classics revisited: C. J. van der Horst on pregnancy and menstruation in elephant shrews.

BACKGROUND: Menstruation occurs only in higher primates, some bats, the spiny mouse and the elephant shrew. Our knowledge of the latter species is due to work by C. J. van der Horst. FINDINGS: Changes in the uterine stroma are initially similar in fertile and infertile cycles and are confined to a small area. In pregnant animals, the presence of the conceptus causes further development to an implantation chamber. In infertile cycles an outgrowth of highly glandular stroma (a polyp) appears. With decline of the corpora lutea it is shed in a process equivalent to menstruation. Van der Horst described the further development of the placenta and a decidua pseudocapsularis in pregnant animals. In addition he built a unique collection that has thrown light on embryonic development and placentation in other South African mammals. CONCLUSIONS: The changes in endometrial stromal cells during the menstrual cycle appear similar between primates and the elephant shrew and deserve to be studied at the molecular level.

The Evolving Presence of Women in Academic Plastic Surgery: A Study of the Past 40 Years.

BACKGROUND: Among surgical subspecialties, plastic surgery holds the highest percentage of women, and, the female contingent of board-certified plastic surgeons and trainees has grown steadily. However, their academic impact has been underestimated. We present the academic footprint of female plastic surgeons over the past 40 years. METHODS: A list of female plastic surgeons currently active at, and retired from, Accreditation Council for Graduate Medical Education-accredited plastic surgery residency programs was compiled. Each surgeon was searched on PubMed to gather their total number of publications, journals, and topics of research after completion of training. Date of publication and 5-year impact factor for each journal were recorded. Publications were organized into 10-year periods (1976 to 1985, 1986 to 1995, 1996 to 2005, and 2006 to 2016). RESULTS: One hundred fifty-five currently active and 80 retired academic female plastic surgeons were identified, who published 2982 articles in 479 peer-reviewed journals. The average 5-year impact factor was 4.093. The number of publications increased with each decade: 37 (1976 to 1985), 218 (1986 to 1995), 472 (1996 to 2005), and 2255 (2006 to 2016). The most commonly published areas were hand/nerve (22 percent), craniofacial (21 percent), and breast (20 percent). Over time, publications in hand/nerve research decreased (76, 60, 38, and 14 percent, respectively); craniofacial-related publications increased (8, 11, 18, and 23 percent, respectively); and publications in breast research increased (0, 8, 9, and 24 percent, respectively). The 2006 to 2016 period yielded the most even distribution of research topics. CONCLUSION: The academic contribution of female plastic surgeons has substantially increased in number and has become more evenly distributed across subspecialty topics.

1916-2016: a centenary of publications.

Last year, the centenary of the 1916 Easter rising in Ireland was marked by a commemorative programme organised by the Irish government including both historical and cultural events. The main themes of these events were remembering the past, celebrating Irish achievements and imagining our future. Reviewing the medical literature offers an insight into a century of achievement and change in Irish medicine, captured from the unique perspective of Ireland's oldest medical journal. This manuscript examines papers published during the last 100 years of the Irish Journal of Medical Science, specifically examining the most cited paper from each year. The majority of top cited papers originate in Ireland (77%) with Trinity College Dublin the commonest institution (n = 12) and obstetrics the most common specialty (n = 9). The average number of citations per article was 20.56 (SD ± 22.36; range 1-118) and the article with most citations was 'Coagulative properties of cancers' published in 1958 by O'Meara et al. The mean number of citations for the top cited publication each year has increased over time. The journal continued to publish even amidst backgrounds of war and civil unrest and represents an important cultural artefact that deserves our ongoing support.

Charles Miller Fisher: the 65th anniversary of the publication of his groundbreaking study "Transient Monocular Blindness Associated with Hemiplegia" / Charles Miller Fisher: 65 anos da publicação de seu estudo inovador "Cegueira monocular transitória associada com hemiplegia"

ABSTRACT Charles Miller Fisher is considered the father of modern vascular neurology and one of the giants of neurology in the 20th century. This historical review emphasizes Prof. Fisher's magnificent contribution to vascular neurology and celebrates the 65th anniversary of the publication of his groundbreaking study, "Transient Monocular Blindness Associated with Hemiplegia."

RESUMO Charles Miller Fisher é considerado o pai da neurologia vascular moderna, e um dos gigantes da neurologia no século XX. Esta revisão histórica enfatiza a magnífica contribuição de Miller Fisher na neurologia vascular, particularmente com a celebração dos 65 anos de publicação do seu estudo inovador intitulado "Cegueira monocular transitória associada com hemiplegia".

Historia del primer artículo científico argentino sobre cáncer y tabaco / History of the first Argentine scientific article on cancer and tobacco

Se revisa la historia del primer artículo científico argentino sobre cáncer y tabaco, de tipo experimental, realizado por el Dr Ángel Roffo en la década del 30.

The history of the first Argentine scientific article on cancer and tobacco, experimental, conducted by Dr. Angel Roffo in the 30s is reviewed.

"Ex Museolo Nostro Machaonico": Collecting, Publishing, and Visualization in Fabricius Hildanus1.

This essay seeks to use the learned surgeon Wilhelm Fabry von Hilden (1560­1634), better known by the Latinized name of Fabricius Hildanus, to establish links among areas that have so far generally been seen by historians as separate. They include the publication of Observationes chirurgicae, the establishment of a surgical museum, and the collection and publication of several images documenting his activities. Fabricius was among the first to embark on these three endeavors. The essay provides an especially rich account of his museum, including its holdings and in some cases the preservation methods he employed.

Novas evidências documentais para a história da homeopatia na América Latina: um estudo de caso sobre os vínculos entre Rio de Janeiro e Buenos Aires / New documental evidence on the history of homeopathy in Latin America: a case study of links between Rio de Janeiro and Buenos Aires

Resumo A homeopatia começou a propagar-se logo após sua formulação por Samuel Hahnemann, nos primeiros anos do século XIX, chegando ao Cone Sul na década de 1830. Esse processo é tradicionalmente vinculado à figura de um “introdutor”, por vezes alcançando estatuto mítico. No entanto, pouco se sabe acerca da chegada da homeopatia à Argentina nesse período. Com base em trabalho de arquivo, identificamos uma clara circulação de homeopatas médicos e leigos no eixo Rio de Janeiro-Buenos Aires. Dada a conhecida atividade proselitista desenvolvida nos círculos ligados aos homeopatas leigos B. Mure e J.V. Martins no Rio de Janeiro, a documentação disponível aponta para a possível extensão desse movimento também na Argentina, o que não tinha sido evidenciado até o presente.

Abstract Homeopathy began to spread soon after it was formulated by Samuel Hahnemann in the early 1800s, reaching the Southern Cone in the 1830s. In processes of this kind, one figure is often cited as being responsible for introducing it, often attaining quasi-mythical status. Little is known, however, about how homeopathy reached Argentina at that time. Through archival research, we discovered that medical and lay homeopaths circulated between Rio de Janeiro and Buenos Aires. Given the well-known proselytizing of the circles gravitating around lay homeopaths B. Mure and J.V. Martins in Rio de Janeiro, the documents indicate that this movement actually went as far as Argentina, which had not been confirmed until now.

Autoimmunity in 2015.

Compared to the clear trend observed in previous years, the number of peer-reviewed articles published during 2015 and retrieved using the "autoimmunity" key word declined by 4 %, while remaining 5 % of immunology articles. On the other hand, a more detailed analysis of the published articles in leading immunology and autoimmunity journals revealed exciting scenarios, with fascinating lines of evidence being supported by convincing data and likely followed by rapid translational or clinical developments. As examples, the study of the microbiome, the development of new serum or other tissue biomarkers, and a more solid understanding of disease pathogenesis and tolerance breakdown mechanisms have been central issues in the past year. Furthermore and similar to the oncology field, progress in the understanding of single autoimmune condition is becoming most specific with psoriatic and rheumatoid arthritis being ideal paradigms with treatment options diverging after decades of common therapies, as illustrated by IL17-targeting approaches. The ultimate result of these advances is towards personalized medicine with an ideal approach being tailored on a single patient, based on a finely tuned definition of the immunogenetics, epigenetics, microbiome, and biomarkers. Finally, experimental reports suggest that cancer-associated immune mechanisms or the role of T and B cell subpopulations should be better understood in autoimmune diseases. While we hailed the 2014 literature in the autoimmunity world as part of an annus mirabilis, we should not be mistaken in the strong stimulus of research in autoimmunity represented by the 2015 articles that will be summarized in this article.

Las publicaciones psiquiátricas nacionales y sus autores en 150 años de la especialidad: los primeros cincuenta años (1852-1902) / Psychiatrics nationals publications and authors during 150 speciality years: The firsts fifty years (1852-1902)

This work is a brief historical investigation with double objective: to recall the importants alienists who took care of the mental patients and too communicate its mains articles, emphasizing its communication by the importance epidemiologist and the clinica relevance of the commented subjects. This an effort work in the House of Orates, and after in the Manicomio Nacional developed next to sacrificed civil employees it was an wasp to get the paper living experiences in one site -as some them they proclaimed- with very bad and deplorable conditions.

Se trata de una investigación histórica con un doble objetivo: recordar a los alienistas chilenos que atendieron a los enfermos mentales y comunicar algunos de sus artículos relevantes clínica y epidemiológicamente, publicados en los primeros cincuenta años de la psiquiatría chilena. Durante esa esforzada época -desarrollada en la principal institución nacional- progresivamente fue consolidándose la especialidad hasta ser conocida en el extranjero. El esforzado trabajo desarrollado en la Casa de Orates y luego en el Manicomio Nacional, junto a los sacrificados funcionarios, fue probablemente un aguijón para llevar al papel las experiencias vividas en un lugar -como algunos lo denunciaron- de pésimas y deplorables condiciones.

La revista Archivo Médico de Camagüey, su historia y logros / Archivo Médico de Camagüey journal, its history and achievements

INTRODUCCIÓN: la revista Archivo Médico de Camagüey fundada en el año 1997, está próxima a cumplir en el año 2015, 18 años de fructífero trabajo. De sus publicaciones se han generado diversos artículos, pero ninguno recoge sus orígenes, logros y perspectivas a lo largo de tantos años. OBJETIVO: rescatar la historia de la revista Archivo Médico de Camagüey, con la intención de promover su conocimiento entre los profesionales y estudiantes de la salud. MÉTODO: se realizó una revisión documental en el Centro Provincial de Información de Ciencias Médicas de Camagüey. Se utilizó el sub método cronológico para establecer el orden de los hechos que se describen. DESARROLLO: se exponen los antecedentes históricos de la revista Archivo Médico de Camagüey, se hace alusión a las publicaciones que la precedieron, la relación de sus logros en orden cronológico así como las perspectivas de desarrollo futuro. CONCLUSIONES: la Revista de Ciencias Médicas de Camagüey y la Revista Referativa, constituyen los antecedentes históricos del surgimiento de la revista Archivo Médico de Camagüey; entre los logros se pueden mencionar el proceso de certificación por el CITMA, ingreso a la base de datos SciELO y adopción de la plataforma de trabajo Open Journal Systems.

INTRODUCTION: Archivo Médico de Camagüey journal, founded in 1997, is near to turn 18 years of profitable work in 2015. Articles that study the publication from different aspects have come out from its publications, but none of them have included its origin, perspectives, and achievements throughout these years. It could be added to this fact that some of the founders are retired or diseased. All this generated the need of presenting the historical evolution of the journal in this article. OBJECTIVE: to save the history of Archivo Médico de Camagüey journal, with the intention of promoting about it among health professionals and students. METHOD: a documentary review was made in the Provincial Information Center of the University of Medical Sciences. The chronological submethod was used to establish the order of the described facts. DEVELOPMENT: the historical record of the Archivo Médico de Camagüey journal is presented. The publications that preceded it, the relation of its achievements chronologically ordered, as well as the perspective for the future development are also referred. CONCLUSIONS: Revista de Ciencias Médicas de Camagüey and Revista Referativa constitute the historical antecedents of the Archivo Médico de Camagüey journal. Among the achievements can be mentioned: the certification process by CITMA, the entry to SciELO data base, and the adoption of the Open Journal System work platform.

El Herbario USJ de Costa Rica: trayectoria y contribuciones / USJ Herbarium of Costa Rica: history and contributions

In 2011 the Herbarium USJ of the University of Costa Rica became 80 years old and came up with 100 000 specimens of all the taxa that traditional botany studies. Data and figures on the history, the founders, and contributions of USJ to the knowledge of Costa Rican flora are summarized.

En 2011 el Herbario USJ de Costa Rica cumplió 80 años y llegó a 100 000 especímenes de todos los taxa que estudia la botánica. Se anotan datos y cifras sobre historia, fundadores y contribuciones de USJ al conocimiento florístico de Costa Rica.