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1.
Rev. bras. ciênc. vet ; 29(1): 27-35, jan./mar. 2022. il.
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1393204

RESUMO

For vertebromedullary injuries, epidemiological knowledge is essential to guide the choice of the most effective diagnostic method. The objective of this retrospective study was to describe the epidemiological profile of animals and thoracolumbar and lumbosacral spine lesions diagnosed by computed tomography scan. A compilation of CT scan reports for the aforementioned regions performed in a comercial diagnostic center from 04/01/2017 to 04/30/2020, contrasted and non-contrasted, from routine, was performed in order to list the most common lesions and their locations, as well as the species, breeds and ages most affected. There were 1164 CT scans performed in the period evaluated, all of them in dogs, 57,56% (n=670) for the spine, with 89,7% reports accessed (n=601), where the regions mentioned here added up to 73,05% studies (n=439). In both regions, male French Bulldog dogs had the most injuries. For the thoracolumbar region, disk mineralization, followed by extrusion, were the most frequent injuries, while the site was T12-13 and the mean age 6,5±3,63 years old. In the lumbosacral, disk protrusion was most frequent, the most affected site was L7-S1 and age 6,65±3,79 years. It was concluded that the spine is the main target of CT scans, and that lesions related to the intervertebral disk were the main ones identified, with chondrodystrophic animals being more predisposed to injury.


Para lesões vertebromedulares é indispensável o conhecimento epidemiológico para direcionar a escolha do método diagnóstico mais eficaz. O objetivo desse estudo retrospectivo foi descrever o perfil epidemiológico dos animais e das lesões em coluna vertebral toracolombar e lombossacral diagnosticadas através de exame tomográfico. Realizou-se a compilação de laudos de tomografias computadorizadas para as referidas regiões realizadas em centro diagnóstico comercial, entre 01/04/2017 a 30/04/2020, contrastadas e não-contrastadas, provenientes da rotina, a fim de relacionar as lesões e seus locais de ocorrência, bem como a espécie, raças e idades mais comuns. Foram realizados 1164 exames tomográficos no período avaliado, sendo 57,56% (n=670) para a coluna, com 89,7% laudos acessados (n=601), nos quais as regiões toracolombar e lombossacral somaram 73,05% dos estudos (n=439). Em ambas as regiões, os cães Bulldog Francês machos foram os que mais apresentaram lesões. Para a região toracolombar, a mineralização de disco, seguida pela extrusão, foram as lesões mais frequentes, enquanto o local foi T12-13 e a média de idade 6,5±3,63 anos. Na lombossacral, a protusão de disco foi mais frequente, o local mais afetado foi L7-S1 e idade de 6,65±3,79 anos. Concluiu-se que a coluna vertebral é o principal alvo de tomografias, e que as lesões relacionadas ao disco intervertebral foram as principais identificadas, sendo os animais condrodistróficos mais predispostos a lesões.


Assuntos
Animais , Gatos , Cães , Traumatismos da Coluna Vertebral/veterinária , Coluna Vertebral/diagnóstico por imagem , Tomografia Computadorizada por Raios X/veterinária , Gatos/lesões , Cães/lesões , Disco Intervertebral/lesões , Vértebras Lombares/lesões , Região Lombossacral/anormalidades
2.
Medicine (Baltimore) ; 100(37): e27198, 2021 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-34664848

RESUMO

ABSTRACT: To describe the retroperitoneoscopic debridement technique and evaluate the clinical outcome of internal fixation for the treatment of lumbar tuberculosis.Twenty-eight patients were performed conventional laparoendoscopic technique (n = 17) or laparoendoscopic single-site technique (n = 11). Antituberculosis chemotherapy and thoracolumbosacral orthosis were given to all patients. The clinical outcomes were evaluated with preoperative and postoperative Visual Analog Scale, and radiographs with respect to sagittal angle and fusion status.Average time of the 28 procedures was 220.6 ±â€Š50.9 min (180-365 min). The average intraoperative blood loss was 108.6 ±â€Š95.3 mL (50-400 mL). All patients showed significant improvement of their Visual Analog Scale back pain score at follow-up and were classified as having a radiographic fusion in this study. The mean sagittal angle was 11.2 ±â€Š3.6° before operation, significantly improved to 3.7 ±â€Š2.4° after operation. There were no recurrent infections during the follow-up period. Complications included loosening of anterior fixation and temporary deficit of the sympathetic nerve.Retroperitoneal laparoscopic approach with CO2 insufflation technique is a challenging but safe and effective procedure for lumbar spine tuberculosis. Retroperitoneal laparoendoscopic single-site can be used for anterior lumbar spine surgery, offer exposure for L1 through L5.


Assuntos
Desbridamento/normas , Fixadores Internos/normas , Tuberculose Osteoarticular/cirurgia , Adulto , Idoso , Desbridamento/métodos , Desbridamento/estatística & dados numéricos , Feminino , Humanos , Fixadores Internos/estatística & dados numéricos , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Espaço Retroperitoneal/anormalidades , Espaço Retroperitoneal/diagnóstico por imagem , Estudos Retrospectivos , Resultado do Tratamento
3.
Medicine (Baltimore) ; 99(29): e21049, 2020 Jul 17.
Artigo em Inglês | MEDLINE | ID: mdl-32702846

RESUMO

Lateral recess stenosis is a common pathology causing clinical syndromes in the elderly population, and there is some concern regarding the number of comorbidities that can occur when performing surgery for this condition in the elderly. However, little research has focused on the issues related to older age, and limited data is available to help the clinician counsel elderly patients undergoing percutaneous endoscopic transforaminal decompression. The present study aimed to explore the safety and efficacy of percutaneous endoscopic transforaminal decompression for lumbar degenerative disease in elderly patients with lumbar lateral recess stenosis and to determine whether age and comorbidity affect the outcome and complication rate.We identified 117 patients in our patient database who underwent percutaneous endoscopic transforaminal decompression for single-level lumbar lateral recess stenosis. Data regarding the Oswestry Disability Index and visual analog scale for back and leg pain were collected preoperatively, postoperatively, and at the last follow-up. Other data, including preoperative comorbidities, operation time, and intraoperative and postoperative complications, were recorded.The average follow-up period was 29.9 ±â€Š5.5 months, with a mean age of 69.8 ±â€Š5.4 years in elderly patients (group A) and 50.4 ±â€Š6.4 years in younger patients (group B). Group A had a higher percentage of comorbidity than group B (83.9% vs 18.0%, P < .001). Both visual analog scale scores for leg pain and Oswestry Disability Index were significantly improved in the 2 groups, and no difference was found between the groups regarding both parameters (P >.05). The elderly patients had the same high rate of favorable outcomes as group B (P > .05). Moreover, there was no difference in surgical complications, recurrence, and neurologic deficit recovery rate between both groups. No major complications or perioperative deaths occurred in both groups.The present study demonstrates that percutaneous endoscopic transforaminal decompression for lateral recess stenosis in elderly patients may be a reasonable treatment associated with substantial benefit.


Assuntos
Fatores Etários , Descompressão Cirúrgica/métodos , Região Lombossacral/cirurgia , Estenose Espinal/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Descompressão Cirúrgica/estatística & dados numéricos , Endoscopia/métodos , Feminino , Humanos , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Estenose Espinal/complicações , Estenose Espinal/epidemiologia , Resultado do Tratamento
4.
Medicine (Baltimore) ; 99(22): e20397, 2020 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-32481429

RESUMO

RATIONALE: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by ossification along the anterolateral aspect of at least 4 contiguous vertebral bodies. A fracture involving the fused vertebra in patients with DISH often leads to severe instability and spinal cord injury. Spinal metastasis (Mets) and DISH can coexist in elderly patients and increase their risk of pathologic vertebral fractures. However, there are few reports on concomitant spinal Mets and DISH. PATIENT CONCERNS: A 78-year-old man who complained of gradual onset of paraparesis, sensory loss below the umbilicus, and incontinence (case 1) and a 63-year-old woman who complained of severe back pain and urinary incontinence (case 2). DIAGNOSIS: Two patients were diagnosed with spinal Mets and DISH. INTERVENTIONS: Decompression surgery was performed at the metastatic sites in case 1 whereas instrumentation surgery was performed in case 2 despite the fracture having a benign appearance with no associated neurologic symptoms. OUTCOMES: A vertebral fracture developed at the metastatic vertebra after decompression surgery in case 1. Severe instability of the surgical site in this case resulted in persistent paralysis even after subsequent revision surgery with instrumentation. In contrast, the clinical course was benign without any neurologic dysfunction at the 2-year follow-up in case 2. LESSONS: Instrumentation surgery should be performed in patients with DISH who develop spinal Mets even if there is no apparent instability.


Assuntos
Hiperostose Esquelética Difusa Idiopática/complicações , Neoplasias da Coluna Vertebral/secundário , Idoso , Blefaroptose , Neoplasias da Mama/patologia , Anormalidades Congênitas , Descompressão Cirúrgica/métodos , Feminino , Fixação Interna de Fraturas/métodos , Humanos , Hiperostose Esquelética Difusa Idiopática/cirurgia , Região Lombossacral/anormalidades , Masculino , Pessoa de Meia-Idade , Neoplasias da Próstata/patologia , Fraturas da Coluna Vertebral/etiologia , Fraturas da Coluna Vertebral/cirurgia , Neoplasias da Coluna Vertebral/complicações , Neoplasias da Coluna Vertebral/cirurgia , Vértebras Torácicas/lesões , Vértebras Torácicas/cirurgia
6.
Vet Surg ; 49(1): 200-206, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31758707

RESUMO

OBJECTIVE: To report the surgical treatment and outcome of six bulldogs with spina bifida (SB) and meningocele (MC) or meningomyelocele (MMC). STUDY DESIGN: Case series. ANIMALS: Five French bulldogs and one English bulldog with MC or MMC. METHODS: Medical records of dogs with spinal MC or MMC diagnosed by MRI at two institutions between 2013 and 2016 were reviewed for surgical treatment and outcomes. RESULTS: Meningocele was diagnosed in two dogs, and MMC was diagnosed in four dogs. A lumbosacral dimple was noted in all dogs along with neurological deficits most commonly consisting of urinary and fecal incontinence (n = 6) and mild/moderate paraparesis (n = 3). Dorsal laminectomy was performed in all dogs to allow dissection of the meningeal sac to the vertebral column defect. In dogs with MMC, nerves were repositioned and protruded meninges were removed prior to suturing remaining meninges. Adhesions and filum terminale were resected in two dogs with suspected tethered cord syndrome. Urinary and fecal incontinence improved in two dogs and remained unchanged in four. Paraparesis improved in two dogs. CONCLUSION: Surgical treatment resulted in partial improvement of the urinary and fecal incontinence (2/6 dogs) and paraparesis (2/3 dogs) or stable neurological condition (3/6 dogs), with only minor temporary complications. CLINICAL SIGNIFICANCE: In the absence of published data comparing surgical and conservative treatment of puppies affected by SB and MC or MMC, early surgical treatment can be considered to prevent deterioration of neurological signs and, eventually, facilitate improvement of neurological signs.


Assuntos
Cães/cirurgia , Meningocele/veterinária , Meningomielocele/veterinária , Animais , Cães/anormalidades , Feminino , Laminectomia/veterinária , Região Lombossacral/anormalidades , Região Lombossacral/cirurgia , Masculino , Meningocele/cirurgia , Meningomielocele/cirurgia , Especificidade da Espécie , Resultado do Tratamento
8.
Radiol Med ; 124(5): 375-381, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30547357

RESUMO

INTRODUCTION: To evaluate the prevalence of subtypes of congenital lumbosacral transition vertebra (LSTV) in young male populations with low back pain (LBP) and their relationship to lumbar disc and facet degeneration. MATERIALS AND METHODS: 1875 patients (male, aged; 18-40 years) with LBP were investigated retrospectively. Standard lumbar MRI protocol of sagittal, and axial T1 weighted images (WI) and T2 WI and coronal short tau inversion recovery (STIR) T2 WI were obtained. Castellvi classification of LSTV were used for subtyping. The level and above the level of LSTV were evaluated for the lumbar disc space and facet degeneration based on grading methods which compares subtype groups with each other. RESULTS: Prevalence of LSTV was 32% (600 of 1875). The most frequent LSTV types were type I (dysplastic enlarged transverse process; 66.5%) and type II (pseudoarticulation; 21.8%). Eight percent of the patients were type III (fusion) and 3.6% patients type IV (one transverse process fused and one with pseudoarticulation). The most commonly detected LSTV types were type I + II (88%) and all bilateral LSTV types were seen much more than unilateral types (bilateral versus unilateral 63.2%, 33.2%). The LSTV type I highly correlated with the disc degeneration and facet arthrosis. But the groups with higher grade of disc degeneration were type IV and III. CONCLUSION: In young male patients with LBP, LSTV was found to be high in frequency and mostly occurred to be subtype I. LSTV type I and associated disk and facet degeneration were found to be remarkable in this group. Coronal T2 STIR images are useful in showing lumbosacral region anomalies and variants, and should be included in the routine lumbar MRI protocol.


Assuntos
Degeneração do Disco Intervertebral/diagnóstico por imagem , Dor Lombar/diagnóstico por imagem , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Adolescente , Adulto , Humanos , Masculino , Estudos Retrospectivos
9.
J Emerg Med ; 55(4): 544-546, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30037517

RESUMO

BACKGROUND: Compartment syndrome is a life-threatening complication of traumatic injury, most commonly, direct trauma. Back pain is a common cause of visits to the emergency department (ED) and often is treated without imaging or diagnostic testing. Lumbar paraspinal compartment syndrome is a rare cause of acute back pain. CASE REPORT: A 43-year-old woman presented to the ED after direct trauma to the lower back. Laboratory studies revealed rhabdomyolysis and acute kidney injury, with examination findings and imaging consistent with lumbar paraspinal compartment syndrome. She was taken to the operating room for emergent fasciotomy. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: It is the job of the emergency physician to identify the red flags in history and physical examination that warrant further diagnostic testing. Early diagnosis and surgical consultation is the key in avoiding morbidity and achieving good outcomes in all forms of compartment syndrome.


Assuntos
Síndromes Compartimentais/diagnóstico , Região Lombossacral/irrigação sanguínea , Acidentes por Quedas , Adulto , Analgésicos Opioides/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Dor nas Costas/tratamento farmacológico , Síndromes Compartimentais/etiologia , Síndromes Compartimentais/cirurgia , Feminino , Humanos , Ibuprofeno/uso terapêutico , Cetorolaco/uso terapêutico , Região Lombossacral/anormalidades , Morfina/uso terapêutico , Obesidade Mórbida/complicações , Músculos Paraespinais/anormalidades , Músculos Paraespinais/lesões , Tomografia Computadorizada por Raios X/métodos
10.
Pain Manag Nurs ; 19(5): 525-534, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29779792

RESUMO

BACKGROUND: Although the use of prescription opioid analgesics to treat acute, postoperative pain is a well-established practice, the role of opioids in the management of persistent, postoperative pain remains ill-defined. Nevertheless, high rates of long-term opioid use following lumbar fusion have been reported. AIM: The goal of this prospective, longitudinal study was to identify predictors of weeks to opioid cessation in a cohort of patients undergoing elective lumbar fusion. METHODS: Prior to surgery, participants self-reported demographic and clinical data and completed a validated measure of pain catastrophizing. Three months following surgery, participants self-reported prescription opioid use. RESULTS: Forty-four percent (n = 22) of participants reported opioid use 12 weeks following lumbar fusion. Bivariate analysis identified a strong correlation between weeks to opioid cessation and preoperative opioid use, r = .46, and a moderate correlation between weeks to opioid cessation and disability, r = .29. The multiple regression model predicting weeks to opioid cessation from age, sex, employment status, educational level, preoperative pain intensity, preoperative opioid use, disability status, and pain catastrophizing was significant, F(8, 38) = 2.254, p = .044, and accounted for 18% of the variance. Among preoperative patient characteristics, only preoperative opioid use significantly predicted weeks to opioid cessation, ß = .466; p = .005. CONCLUSION: Thus, nurses and nurse practitioners may be able to identify patients at risk for long-term opioid use following lumbar fusion by screening patients for preoperative opioid use.


Assuntos
Analgésicos Opioides/uso terapêutico , Região Lombossacral/cirurgia , Fusão Vertebral/efeitos adversos , Idoso , Estudos de Coortes , Feminino , Humanos , Modelos Logísticos , Estudos Longitudinais , Região Lombossacral/anormalidades , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/tratamento farmacológico , Estudos Prospectivos , Psicometria/instrumentação , Psicometria/métodos , Autorrelato , Fusão Vertebral/métodos , Inquéritos e Questionários , Fatores de Tempo
11.
J Clin Neurosci ; 51: 67-68, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29503029

RESUMO

Bertolotti syndrome describes lower back pain secondary to an anatomical lumbosacral transitional vertebrae. We present the case of a 37 year old female with chronic lower back pain with radiological evidence of an anatomical lumbosacral pseudojoint. The patient underwent minimally invasive resection of her pseudojoint with complete resolution of symptoms postoperatively. We, as the authors would like to highlight that in patients with pain secondary to an aberrant lumbosacral articulation, consideration should be given to treatment via a minimally invasive technique.


Assuntos
Dor Lombar/cirurgia , Vértebras Lombares/anormalidades , Vértebras Lombares/cirurgia , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Sacro/anormalidades , Sacro/cirurgia , Adulto , Feminino , Humanos , Dor Lombar/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Região Lombossacral/cirurgia , Sacro/diagnóstico por imagem , Resultado do Tratamento
12.
Spine Deform ; 6(2): 185-188, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29413742

RESUMO

STUDY DESIGN: Structured literature review. OBJECTIVES: The Scoliosis Research Society (SRS) requested an assessment of the current state of peer-reviewed evidence regarding pediatric lumbar spondylolisthesis with the goal of identifying what is known and what gaps remain in further understanding the diagnostic methods for pediatric spondylolisthesis. SUMMARY OF BACKGROUND DATA: Spondylolisthesis in the lumbar spine is common among children and adolescents and no formal synthesis of the published literature regarding diagnostic methods has been previously performed. METHODS: A comprehensive literature search was performed. Abstracts were reviewed and data from included studies were analyzed by the committee. From 6600 initial citations with abstract, 663 articles underwent full-text review. The best available evidence for the clinical questions regarding diagnostic methods was provided by 26 included studies. Six of the studies were graded as Level III (retrospective comparative), and represent the current best available evidence whereas 20 of the studies were graded as Level IV (retrospective case series) evidence. No Level V (expert opinion) studies were included in the final list. None of the studies were graded as Level I or Level II. RESULTS: Plain radiography is the workhorse imaging modality for diagnosing spondylolisthesis. No association between radiologic grade of spondylolisthesis and clinical presentation were noted; however, grade III and IV slips more often required surgery, and increasing slip angles were associated with worse baseline outcome scores. There is Level III evidence that the Meyerding grade appears to be more accurate for measuring slip percentage whereas the Lonstein Slip angle and Dubousset Lumbosacral Kyphosis angles are the best for measuring lumbosacral kyphosis in spondylolisthesis. In addition, higher sacral table index, pelvic incidence, sacral slope, and lower sacral table angle were associated with spondylolisthesis. True incidence could not be determined by the current literature available. However, studies in adolescent athletes demonstrated an incidence of 6% to 7% across studies. CONCLUSIONS: The current "best available" evidence to guide the diagnosis and characterization of pediatric spondylolisthesis is presented. Future studies are needed to provide more high-quality evidence to answer these clinically relevant questions. LEVEL OF EVIDENCE: Level III, review of Level III studies.


Assuntos
Cifose/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Região Lombossacral/diagnóstico por imagem , Sociedades/organização & administração , Espondilolistese/diagnóstico por imagem , Adolescente , Criança , Pré-Escolar , Medicina Baseada em Evidências , Feminino , Humanos , Incidência , Vértebras Lombares/patologia , Região Lombossacral/anormalidades , Masculino , Imagem Multimodal/métodos , Radiografia/métodos , Estudos Retrospectivos , Espondilolistese/classificação , Espondilolistese/diagnóstico , Espondilolistese/epidemiologia
13.
Pain Physician ; 21(1): 73-82, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29357336

RESUMO

BACKGROUND: Lumbosacral transitional vertebrae (LSTV) are a relatively common variant and have been considered as one of the reasons for back pain. It is not unusual for clinicians to encounter patients with LSTV who require caudal epidural block (CEB) for pain management. OBJECTIVE: We investigated the termination level of the dural sac (DS) and anatomical features of the lumbosacral region relevant to CEB in patients with LSTV and compared these findings between sacralization and lumbarization groups. STUDY DESIGN: A retrospective evaluation. SETTING: A university hospital with inpatient and outpatient LSTV cases presenting low back pain. METHODS: Four hundred ninety-four LSTV patients were included and categorized into sacralization (n = 201) or lumbarization groups (n = 293). Magnetic resonance imaging (MRI) of all of the LSTV patients were reviewed to determine the level of DS termination, the shortest distance between the apex of the sacral hiatus and DS, and the presence and the caudal level of sacral perineural cysts. Each lumbosacral vertebra column was divided into 3 equal portions (upper, middle, and lower thirds). The MRI findings in both of the groups were compared and analyzed. RESULTS: The distribution frequency of the levels of DS termination demonstrated a significant difference between the 2 groups. The mean caudal DS level in the lumbarization group was significantly lower than the sacralization group (lower third of the S2 [131 {44.7%} of 293 patients] vs. lower third of the S1 [78 {38.8%} of 201 patients]). The DS terminated at the S3 in more than 19% of the lumbarization group, whereas in only one case of the sacralization group. Although the incidence of perineural cysts was not significantly different between the 2 groups, the mean level of caudal margin of perineural cysts in the lumbarization group was significantly lower than the sacralization group (middle third of the S3 [10 {35.7%} of 28 cases] vs. middle third of the S2 [11 {44%} of 25 cases]). LIMITATIONS: This study reveals several limitations including the practical challenge of accurate enumeration of the transitional segment and the constraints on generalizability posed by the single-country study. CONCLUSION: When planning CEB for patients with LSTV, pre-procedural MRI to check the anatomical structures, including the level of DS termination and caudal margin of perineural cysts, would be of great use for lowering the risk of unexpected dural puncture during the procedure, especially in the lumbarization cases. KEY WORDS: Termination of the dural sac, dural sac termination, lumbosacral transitional vertebrae, transitional vertebra, caudal epidural block.


Assuntos
Anestesia Caudal/métodos , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Adulto , Idoso , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Manejo da Dor/métodos , Estudos Retrospectivos
14.
J Spinal Cord Med ; 41(4): 496-500, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-28875772

RESUMO

CONTEXT: Caudal regression syndrome is a rare disorder, not well described in the literature. FINDINGS: Authors treated two patients with congenital absence of thoracolumbar vertebrae and lower limbs paraplegia. Patients had hypoplasia of the lower trunk and extremities with motion between upper and lower torso. Imaging showed caudal spine agenesis, but cleft sacrum was present. Due to severe kyphotic deformity and spinal instability, deformity correction and posterior fusion was performed at the age 6 and 8. Finally, fusion was achieved in one case and stable but non-fusion kyphotic posture was observed in second. CONCLUSION: surgery in caudal regression syndrome is challenging and bears high risk of complications.


Assuntos
Anormalidades Múltiplas/diagnóstico , Região Lombossacral/anormalidades , Meningocele/diagnóstico , Região Sacrococcígea/anormalidades , Criança , Feminino , Humanos , Masculino , Síndrome
15.
Medicine (Baltimore) ; 96(43): e8393, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29069034

RESUMO

Lumbosacral hemivertebrae causes unique problems as early trunk decompensation and long compensatory curve above. There are only a few reports on it. This case series is a fair supplement in the literatures.To evaluate the clinical and radiological outcomes of lumbosacral hemivertebrae resection through 1-stage posterior approach.Between 2005 and 2014, a consecutive series of congenital scoliosis due to lumbosacral hemivertebrae underwent hemivertebrae excision through 1-stage posterior only approach. Demographic, operative, radiological, and quality of life data were reviewed.The mean lumbosacral curve was 29 ±â€Š7° preoperatively, 10 ±â€Š3° postoperatively, and 13 ±â€Š5° at the final follow up. The final correction rate was 55 ±â€Š9%. The gravity trunk shift was 11 ±â€Š3 mm preoperatively, 37 ±â€Š12 mm (range, 6-49 mm) postoperatively, 14 ±â€Š9 mm at final follow up. The rib cage shift was 36 ±â€Š12 mm preoperatively, 19 ±â€Š5 mm postoperatively, and 15 ±â€Š4 mm at the final follow up. The mean blood loss was 527 ±â€Š125 mL and the mean surgery time was 336 ±â€Š98 minutes. The mean follow up period was 41 ±â€Š6 months. Two patients underwent transient neurological complications, 2 had wound bad healing, and 1 got wound infection. No pseudoarthrosis and instrumentation failure was observed.One-stage posterior hemivertebrae excision could gain reasonable outcome. It is crucial to completely resect the hemivertebrae and the Y-shaped disc. Bending the rod to appropriate lordosis is helpful to close the convex side. Early surgical intervene is a preferred choice to restore the trunk balance and avoid extensive fusion. The neurological complication rate is high. Convex radiculopathy is often caused by retraction, it could recover at follow up.


Assuntos
Doenças do Desenvolvimento Ósseo/cirurgia , Discotomia/métodos , Vértebras Lombares/anormalidades , Região Lombossacral/anormalidades , Escoliose/cirurgia , Doenças do Desenvolvimento Ósseo/congênito , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Vértebras Lombares/cirurgia , Região Lombossacral/cirurgia , Masculino , Estudos Retrospectivos , Escoliose/congênito , Resultado do Tratamento
16.
Neurochem Res ; 42(11): 3160-3169, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28712050

RESUMO

Fecal incontinence and constipation still remain the major complications after procedures for anorectal malformations (ARMs). Previous studies have demonstrated a decrease of neural cell in lumbosacral spinal cord of ARMs patients and rat models. However, the underlying mechanism remains elusive. In this study, the neural cell apoptosis and Bcl-2/Bax expression were explored during lumbosacral spinal cord development in normal and ARMs fetuses. ARMs rat fetuses were induced by treating pregnant rats with ethylenethiourea on embryonic day 10. TUNEL staining was performed to identify apoptosis, and the expression of Bcl-2/Bax was confirmed with immunohistochemical staining, RT-qPCR and Western blot analysis on E16, E17, E19 and E21. Apoptosis index (AI) in the ARMs group was significantly higher compared to normal group. Our results showed that TUNEL-positive cells were mainly localized in the ventral horn, which is the location of neural cells controlling defecation. And the expression of Bcl-2 decreased, whereas the level of Bax increased in the ARMs fetuses. In addition, there was a significantly negative correlation between protein expression of Bcl-2/Bax ratio and AI in the ARMs group. Abnormal apoptosis might be a fundamental pathogenesis for the number decrease of neural cells in lumbosacral spinal cord, which leads to complications after procedures for ARMs. The negative correlation between the ratio of Bcl-2/Bax and AI manifested that Bcl-2/Bax pathway might be the mechanism for neural cell apoptosis in ARMs.


Assuntos
Malformações Anorretais/metabolismo , Apoptose/fisiologia , Região Lombossacral/anormalidades , Neurônios/metabolismo , Proteínas Proto-Oncogênicas c-bcl-2/biossíntese , Proteína X Associada a bcl-2/biossíntese , Animais , Malformações Anorretais/patologia , Feminino , Expressão Gênica , Região Lombossacral/embriologia , Região Lombossacral/patologia , Neurônios/patologia , Gravidez , Proteínas Proto-Oncogênicas c-bcl-2/genética , Ratos , Ratos Wistar , Medula Espinal/anormalidades , Medula Espinal/embriologia , Medula Espinal/patologia , Fatores de Tempo , Proteína X Associada a bcl-2/genética
17.
J Med Imaging Radiat Oncol ; 61(2): 216-224, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27469617

RESUMO

Congenital malformations of the lumbosacral spine include spinal dysraphism and caudal anomalies. Most often, these malformations are discovered prenatally or in early infancy, but some are not diagnosed until late childhood or adulthood. The purpose of this pictorial review is to illustrate the multi-modality imaging characteristics in these complex anomalies and to provide a systematic radiological approach aiming at improving diagnostic accuracy.


Assuntos
Diagnóstico por Imagem/métodos , Região Lombossacral/anormalidades , Região Lombossacral/diagnóstico por imagem , Coluna Vertebral/anormalidades , Coluna Vertebral/diagnóstico por imagem , Humanos
18.
Georgian Med News ; (248): 82-8, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26656557

RESUMO

The goal of the paper is to substantiate the essence of ridetherapy biomechanics as the pathogenetic therapeutic and prophylactic method at lumbar dysplastic (the I and II degrees) and static (short-legged induced) scoliosis. Uneven lower extremities caused by any reason and asymmetric support induce the change in the arrangement of trochantin to the vertebra and correspondingly the uneven loading of lumbar muscles. The asymmetric strength of lumbar muscles evoked by the change in rotator condition becomes the cause of the formation of scoliosis primary arc which, in its turn, causes a compensatory spinal curvature. In case of dysplastic scoliosis a leading role belongs to the beginning of dystrophic changes in intervertebral discs and its further decentration. At riding position the lower extremities are completely disengaged from the antigravity redistribution, the child is in direct contact with vibrations and jolts coming from the horseback; the antigravity loading is distributed on the muscles of the torso and thus, it creates an opportunity to purposefully affect the correction of the spine. During scoliosis the pathogenic essence of ridetherapy is due to the comprehensiveness of its procedures, expressed in the fact that during one procedure several factors are influenced simultaneously: nucleus pulpous, the torso and iliopsoas muscles, the antigravity system, etc. According to the clinical-functional and radiographic studies carried out in the dynamics on 11-16 years old adolescents it has been established that in those groups where the rehabilitation was conducted in a complex with ridetherapy the authentically higher results were obtained as compared to the groups where the rehabilitation was held using therapeutic exercises and massage.


Assuntos
Terapia Assistida por Cavalos/métodos , Quadril/fisiopatologia , Vértebras Lombares/fisiopatologia , Escoliose/terapia , Adolescente , Animais , Fenômenos Biomecânicos , Criança , Feminino , Fêmur/anormalidades , Fêmur/fisiopatologia , Elevação dos Membros Posteriores/métodos , Quadril/anormalidades , Cavalos , Humanos , Disco Intervertebral/anormalidades , Disco Intervertebral/fisiopatologia , Vértebras Lombares/anormalidades , Região Lombossacral/anormalidades , Região Lombossacral/fisiopatologia , Masculino , Músculo Esquelético/fisiopatologia , Escoliose/patologia , Escoliose/fisiopatologia , Índice de Gravidade de Doença , Resultado do Tratamento , Suporte de Carga
19.
Top Companion Anim Med ; 30(1): 10-5, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26041591

RESUMO

Lumbosacral transitional vertebrae (LTV) frequently occur in German shepherd dogs. The aim of the study was to evaluate the prevalence and interdependence between LTV and canine hip dysplasia (CHD) as well as sacroiliac joint degenerative changes visualized on ventrodorsal radiographs of the pelvis in both working and companion German shepherd dogs. The presence of LTV was found in 12% of working dogs and in 33% of companion dogs. Similar incidence of hip dysplasia in both the groups was found. It has been shown that dogs with LTV have a higher frequency of severe CHD. A higher percentage of sacroiliac joint degenerative changes was observed in dogs with no signs of LTV and in working dogs.


Assuntos
Displasia Pélvica Canina/diagnóstico por imagem , Região Lombossacral/anormalidades , Articulação Sacroilíaca/diagnóstico por imagem , Animais , Cães , Feminino , Displasia Pélvica Canina/epidemiologia , Deformidades Articulares Adquiridas/veterinária , Região Lombossacral/diagnóstico por imagem , Masculino , Linhagem , Pelve/diagnóstico por imagem , Polônia/epidemiologia , Polícia , Prevalência , Articulação Sacroilíaca/patologia , Índice de Gravidade de Doença
20.
Int. j. morphol ; 33(1): 48-50, Mar. 2015. ilus
Artigo em Inglês | LILACS | ID: lil-743761

RESUMO

In the lumbosacral region, anatomical variations occur with changes in the number of sacral vertebra either by deletion of first sacral vertebra or by the union of fifth lumbar or first coccygeal vertebra with sacrum. Lumbasacral transitional vertebrae (LSTV) is the most common congenital anomalies of the lumbosacral region. It most commonly involves the fifth lumbar vertebra showing signs of fusion to the sacrum known as sacralisation or the first sacral vertebra shows signs of transition to a lumbar configuration commonly known as lumbarisation. Complete transition can result in numerical abnormalities of the lumbar and sacral vertebral segments. Lumbarisation of first sacral vertebra is seen with a very low incidence of 2%. Knowledge of presence of such vertebral variation will be helpful for the clinicians to diagnose and treat patients with low back pain. Although sacralisation of fifth lumbar vertebrae is most commonly seen when compared to lumbarisation of first sacral vertebrae, we report here a case of lumbarisation of first sacral vertebrae for its rarity among the LSTV and clinical implications.


En la región lumbosacra, las variaciones anatómicas se basan en cambios en el número de las vértebras sacras, ya sea por ausencia de la primera vértebra sacra o por unión de la quinta lumbar o primera vértebra caudal con el sacro. Las vértebras de transición lumbasacra (VTLS) son las anomalías congénitas más frecuentes de la región lumbosacra. La VTLS más común se produce a nivel de la quinta vértebra lumbar, con signos de fusión al sacro, proceso conocido como sacralización; mientras que la primera vértebra sacra también puede mostrar signos de transición a una configuración lumbar. A esto último se lo denomina lumbarización. La transición completa puede provocar anomalías numéricas a nivel de los segmentos vertebrales lumbares y sacros. La lumbarización de la primera vértebra sacra se observa con una incidencia muy baja, de solo 2%. El conocimiento de la presencia de dicha variación vertebral será de utilidad para los médicos al momento de diagnosticar y tratar a los pacientes con dolor en la parte baja de la espalda. Aunque la sacralización de la quinta vértebra lumbar se produce más frecuentemente en comparación con la lumbarización de la primera vértebra sacra, se presenta aquí un caso de lumbarización de la primera vértebra sacra, rara entre las VTLS, y con implicaciones clínicas.


Assuntos
Humanos , Vértebras Lombares/anormalidades , Região Lombossacral/anormalidades , Sacro/anormalidades
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