Assuntos
Adenocarcinoma de Pulmão/diagnóstico por imagem , Síndrome de Caplan/diagnóstico por imagem , Tumor Carcinoide/diagnóstico por imagem , Neoplasias Pulmonares/diagnóstico por imagem , Adenocarcinoma de Pulmão/patologia , Adenocarcinoma de Pulmão/cirurgia , Síndrome de Caplan/patologia , Síndrome de Caplan/cirurgia , Tumor Carcinoide/patologia , Tumor Carcinoide/cirurgia , Feminino , Humanos , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
We describe a 56-year old man with rheumatoid arthritis and pulmonary nodules detected by HRCT. Needle biopsy confirmed the diagnosis of Caplan syndrome.
Assuntos
Síndrome de Caplan/diagnóstico por imagem , Síndrome de Caplan/patologia , Biópsia por Agulha , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Nódulo Pulmonar Solitário/diagnóstico por imagem , Tomografia Computadorizada por Raios XRESUMO
This retrospective study compares the pulmonary function of 24 coal workers with Caplan's syndrome with that of 36 subjects with non-rheumatoid progressive massive fibrosis (PMF). Allowing for differences in radiographical category, age, years worked underground, and smoking, obstruction to air flow as reflected in the one-second forced expiratory volume, the vital capacity, and the ratio of residual volume to total lung capacity, was significantly less in subjects with Caplan's syndrome. No significant differences in transfer factor were found. These findings may be explained by the different pathological features of the two entities. Selection bias does not appear to be responsible for the differences observed between the groups, but studies designed to eliminate this would be desirable.