Transient Tachypnea of the Newborn Is Associated With an Increased Risk of Hospitalization Due to Respiratory Syncytial Virus Bronchiolitis.

BACKGROUND: Transient tachypnea of the newborn (TTN) is a self-limiting respiratory disorder, resulting from a failure to clear the lungs of perinatal fluid. As similar pathophysiologic features are present in children with respiratory syncytial virus (RSV) bronchiolitis, we hypothesized that these two conditions may be connected. METHODS: This was a population-based cohort study that included all children born in term (≥37 weeks of gestation) without congenital malformations in Finland between 1996 and 2015. Children diagnosed with TTN (International Statistical Classification of Diseases and Related Health Problems, 10th Revision [ICD-10] code P22.1) after birth and children hospitalized because of RSV bronchiolitis (ICD-10 code J21.0) during first year of life were identified from the Medical Birth Register and National Hospital Discharge Register, respectively, and the data were linked. Logistic regression was used to analyze the association between these two conditions. RESULTS: Of the 1,042,045 children included in the study cohort, 16,327 (1.57%) were diagnosed with TTN at birth and 12,345 (1.18%) were hospitalized because of RSV bronchiolitis during the first year of life. The rate of RSV hospitalization was higher in children with a history of TTN compared with children without TTN diagnosis [260/16,327 (1.59%) vs. 12,085/1,025,718 (1.18%), respectively; P value <0.0001]. After adjusting for gestational age at birth, mode of delivery, gender, birth weight, multiple births, older siblings and maternal smoking, TTN was associated with increased risk for RSV hospitalization (odds ratio: 1.31, 95% confidence interval: 1.16-1.48). CONCLUSIONS: TTN diagnosis after birth was associated with increased risk for RSV hospitalization during the first year of life.

Surfactant treatment for neonatal respiratory disorders other than respiratory distress syndrome.

BACKGROUND: It is suggested that there may be expanded use of surfactant replacement for the neonatal diseases such as meconium aspiration syndrome (MAS), pneumonia and possibly bronchopulmonary dysplasia (BPD). OBJECTIVE: To evaluate the characteristics and short-term outcome of the neonates given exogenous surfactant because of the diseases other than respiratory disease syndrome (RDS). METHODS: This retrospective study included 35 neonates admitted to the neonatal intensive care unit from January 2012 to December 2012 for an expanded use of surfactant. Data related to gestational age, birth weight, gender and perinatal risk factors were obtained from the patients' records. The short-term prognosis was also noted. RESULTS: The diagnosis was sepsis in 16 patients, eight MAS, seven transient tachypnea of the newborns (TTN) and four BPD. Mean gestational age was 35.6 ± 4.5 weeks and mean birth weight was 2661 ± 981 g. Of overall cases, 65% were boys and 35% girls. The mortality rate was 17%. Of six fatal cases, three was with BPD, two with sepsis and one with MAS. CONCLUSION: We think that surfactant replacement may be life saver in the neonatal diseases other than RDS such as BPD, MAS and sepsis by rapidly improving oxygenation. Further investigation is necessary to validate the significance of expanded use of surfactant.

Taquipnea transitoria del recién nacido en el Hospital General Docente "Ciro Redondo García": Artemisa 2009 / Transitory taquipnea of the New Born One In The Educational General Hospital "Ciro Redondo García". Artemisa 2009

Entre 40-50 por ciento de los casos con síndrome de dificultad respiratoria (SDR) evolucionan como una Taquipnea Transitoria (TTRN). Se realizó un estudio retrospectivo descriptivo, con el objetivo de conocer el comportamiento de la (TTRN) en la Unidad de Cuidados Especiales de Neonatología (UCEN) del Hospital General Docente Ciro Redondo García, en el período comprendido enero 2008 hasta diciembre 2009. El universo fue 113 recién nacidos (RN) con SDR y 72 constituyeron la muestra con diagnóstico de (TTRN) por un muestreo no probabilístico. Se confeccionó un formulario y se recogieron variables relacionadas con el parto y examen físico del RN. Los datos se procesaron estadísticamente por el sistema Excel. Aproximadamente 3 de cada 4 RN con (TT) nacen por cesárea, a término, del sexo masculino, normopesos, conteo de apgar normal y tiempo de evolución inferior a 120 horas. Se concluye que el comportamiento de la TTRN en nuestro servicio resultó elevado(AU)

Among 40-50 percent of the cases with syndrome of breathing (SDR) they evolve like a transitory Taquipnea (TTRN). He/She was carried out a descriptive retrospective study, whith the objective of knowing the behaviour of the TTRN in the Unit of Special Cares of Neonatology (UCEN) of the educational general Hospital Ciro Redondo García, in the Period understood January 2008 until December 2009. The universe was 113 new born (RN) with SDR and 72 constituted the simple with diagnostic of TTRN for a sampling non probabilistic. A form was made and variables related with the childbirth and physical exam of the RN were picked up. The data were processed statistically by the system Excel. Approximately 3 of each 4 RN with (TT) they are born for caesarean operation, to term, of the masculine sex, norm weight, count of normal apgar and time of inferiority evolution at 120 hours. You conclude that the behaviour of the TTRN in our service is high(AU)