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1.
Neth J Med ; 77(5): 183-185, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31264583
3.
Ann Clin Lab Sci ; 48(4): 496-500, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30143492

RESUMO

BACKGROUND: Elevated serum creatinine levels are a common finding in patients with urinoma (i.e. presence of urine outside of the urinary tract). Therefore, in the clinical circumstance of an urinoma, utilizing a creatinine-based estimated GFR (eGFR) to determine renal function is unreliable, as it fails to distinguish true renal failure from pseudorenal failure in patients with a urine leakage. Cystatin C, a 13 kDA molecular mass protein ubiquitously expressed by nucleated cells, offers superior accuracy in the setting of an urinoma, since unlike creatinine, it is essentially absent in excreted urine and poorly reabsorbed from the peritoneum and retroperitoneal space. METHODS: We present the first case report to demonstrate the utility of cystatin C in an adult patient with native kidney function that experienced significant retro-peritoneal bladder leakage. RESULTS: Our results demonstrate that cystatin C may be a more accurate measurement of GFR than the commonly used creatinine in the setting of an urinoma. CONCLUSION: In order to achieve an accurate estimated GFR in the setting of a urinoma, physicians should consider the use of Cystatin C, which is less vulnerable to inaccurate interpretation.


Assuntos
Cistatina C/sangue , Urinoma/sangue , Idoso , Catéteres , Creatinina/sangue , Taxa de Filtração Glomerular , Humanos , Masculino , Urinoma/diagnóstico por imagem , Urinoma/fisiopatologia
6.
Ultrasound Obstet Gynecol ; 28(6): 848-52, 2006 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16941574

RESUMO

OBJECTIVE: To evaluate the functional prognosis of kidneys affected prenatally by urinomas. METHODS: This was a retrospective review of cases of fetal urinoma reported in the literature, as well as two of our own cases. RESULTS: Twenty-three patients with a prenatal diagnosis of urinoma (five bilateral) were included in the analysis. Postnatal ipsilateral renal function was observed in only six of the 28 renal units (i.e. around 20%). CONCLUSIONS: Although the precise causes of urinomas are still unknown, this review shows that in the event of a fetal urinoma, the probability of a non-functional dysplastic ipsilateral kidney lies at around 80%. In-utero puncture only appears to be justified in cases where fluid accumulation has mass effects on adjacent major structures.


Assuntos
Doenças Fetais/diagnóstico por imagem , Ultrassonografia Pré-Natal/métodos , Urinoma/diagnóstico por imagem , Feminino , Doenças Fetais/fisiopatologia , Humanos , Recém-Nascido , Gravidez , Circulação Renal , Urinoma/fisiopatologia
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