Reactividad de sueros de pacientes chagásicos crónicos con extractos de aislamientos mexicanos de Trypanosoma cruzi / Reactivity of sera from Chagas patients to extracts of mexican Trypanosoma cruzi isolates
Rev. biol. trop
; 41(3B): 861-865, Dic. 1993.
Article
en Es
| LILACS
| ID: lil-320072
Biblioteca responsable:
BR1.1
ABSTRACT
An antigenic extract prepared from four different Mexican isolates of Trypanosoma cruzi cultured on BHI (three came from human cases-Agripina, Fidelfa and Ninoa, and other from triatoma-Cocula) were assayed with human sera. ELISA results always were consistent with clinical diagnosis. Sera from patients with a diagnosis of Chagas disease were reactive and non-chagasic sera were negative. Western blot of chagasic sera recognized antigens of molecular weight > 81 kd, 81 kd, 54 kd, 42 kd, and 26 kd. Sera with high OD in ELISA reacted with more peptide bands. The soluble extract antigens prepared from Mexican isolates of T. cruzi and from the Brazilian Y strain have an homogenous and similar reactivity.
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Colección:
01-internacional
Asunto principal:
Extractos de Tejidos
/
Trypanosoma cruzi
/
Enfermedad de Chagas
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
País/Región como asunto:
Mexico
Idioma:
Es
Revista:
Rev. biol. trop
Asunto de la revista:
BIOLOGIA
/
MEDICINA TROPICAL
Año:
1993
Tipo del documento:
Article
País de afiliación:
México