Genetic characterization of Trypanosoma cruzi natural clones from the state of Paraíba, Brazil
Mem. Inst. Oswaldo Cruz
; 100(3): 273-275, May 2005. tab
Article
en En
| LILACS
| ID: lil-411023
Biblioteca responsable:
BR1.1
ABSTRACT
Eighteen Trypanosoma cruzi stocks from the state of Paraíba, Brazil, isolated from man, wild mammals, and triatomine bugs were studied by multilocus enzyme electrophoresis and random primed amplified polymorphic DNA. Despite the low number of stocks, a notable genetic, genotypic, and phylogenetic diversity was recorded. The presence of the two main phylogenetic subdivisions, T. cruzi I and II, was recorded. The strong linkage disequilibrium observed in the population under survey suggests that T. cruzi undergoes predominant clonal evolution in this area too, although this result should be confirmed by a broader sample. The pattern of clonal variation does not suggests a recent origin by founder effect with a limited number of different genotypes.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Trypanosoma cruzi
/
Variación Genética
/
ADN Protozoario
Límite:
Animals
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Humans
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Año:
2005
Tipo del documento:
Article
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Project document
País de afiliación:
Brasil
/
Francia