Laser-assisted demucosalized gastrocystoplasty with autoaugmentation in a canine model.
Urology
; 55(3): 437-42, 2000 Mar.
Article
en En
| MEDLINE
| ID: mdl-10699633
ABSTRACT
OBJECTIVES:
Laser-assisted autoaugmentation gastrocystoplasty has been performed successfully. Experiments were performed to determine the optimal laser for tissue welding during demucosalized autoaugmentation gastrocystoplasty using both a 1.9-microm diode and a 1.32-microm neodymiumyttrium-aluminum-garnet (NdYAG) laser with and without thermal control.METHODS:
Autoaugmentation gastrocystoplasty was performed on 18 female mongrel dogs. Anastomoses were performed by either suture or laser welding with a 50% human albumin solution. A 1.9-microm diode laser was compared with a 1.32-microm NdYAG laser with and without thermal control. In vivo canine bladder capacity measurements were performed both before gastrocystoplasty and at euthanasia. The animals were studied on days 4 and 14. Samples of the anastomotic area from each group were taken to measure tensile strength. Histologic samples were assessed for tissue damage.RESULTS:
There was a significant increase in bladder volume in the 4-day group compared with pregastrocystoplasty values. Both the 1.9-microm diode laser and suture control dogs with the 14-day repairs had significantly more tensile strength than their 4-day counterparts. In contrast, no statistical difference was found between the 4 and 14-day 1.32-microm NdYAG groups. The suture control group had evidence of minor tissue devitalization at the anastomosis at both 4 and 14 days. The 1.9 and 1.32-microm laser groups both had evidence of tissue devitalization at 4 and 14 days. The 1.32-microm laser group had primarily severe tissue injury. The laser groups at 14 days demonstrated an inflammatory reaction that was localized to the albumin.CONCLUSIONS:
Demucosalized gastrocystoplasty with autoaugmentation can be safely and successfully performed with a 1.9-microm diode laser without significant differences in tensile strength when compared with suture controls. The 1.32-microm NdYAG laser can also be successfully used; however, the long-term results appear to be inferior to the 1.9-microm diode laser.
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Colección:
01-internacional
Asunto principal:
Estómago
/
Vejiga Urinaria
/
Terapia por Láser
Límite:
Animals
Idioma:
En
Revista:
Urology
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos