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Temporal bone findings in multiple endocrine neoplasia type 2B.
Fukaya, H; Suzuki, C; Yasuta, H; Ohtani, I.
Afiliación
  • Fukaya H; Department of Otolaryngology, Fukushima Medical University School of Medicine, Japan.
Eur Arch Otorhinolaryngol ; 257(5): 273-5, 2000.
Article en En | MEDLINE | ID: mdl-10923942
ABSTRACT
To our knowledge, present case is the first published report of temporal bone findings in multiple endocrine neoplasia type 2B (MEN-2B). We describe a 43-year-old Japanese man with medullary thyroid carcinoma (MTC), pheochromocytoma, mucosal neuroma and a Marfanoid body habitus. The collateral adrenal tumors and MTC were removed surgically. However, 14 years after surgery, the MTC and pheochromocytoma recurred and the patient died of intracranial hemorrhage due to hypertension. During the autopsy, metastatic MTC was detected in the liver, lungs, kidneys, pancreas and cervical lymph nodes. Recurrent pheochromocytoma was present in the right kidney. Mucosal neuromas were found in the tongue, gastrointestinal tract and vesical nerve plexus. The following histopathological findings were seen in both temporal bones metastatic MTC was found as well as neuromas and the cochlear aqueduct was widely patent.
Asunto(s)
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Colección: 01-internacional Asunto principal: Neoplasias Craneales / Hueso Temporal / Neoplasia Endocrina Múltiple Tipo 2b Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Eur Arch Otorhinolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Japón
Buscar en Google
Colección: 01-internacional Asunto principal: Neoplasias Craneales / Hueso Temporal / Neoplasia Endocrina Múltiple Tipo 2b Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Eur Arch Otorhinolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Japón