Molecular biology of prostate cancer.

Karayi, M K; Markham, A F

Karayi, M K; Markham, A F.

Afiliación

Karayi MK; Molecular Medicine Unit, University of Leeds, St James's University Hospital, Leeds, UK. manojkarayi@yahoo.co.uk

Prostate Cancer Prostatic Dis ; 7(1): 6-20, 2004.

Article en En | MEDLINE | ID: mdl-14999233

ABSTRACT

ABSTRACT

Development of any cancer reflects a progressive accumulation of alterations in various genes. Oncogenes, tumour suppressor genes, DNA repair genes and metastasis suppressor genes have been investigated in prostate cancer. Here, we review current understanding of the molecular biology of prostate cancer. Detailed understanding of the molecular basis of prostate cancer will provide insights into the aetiology and prognosis of the disease, and suggest avenues for therapeutic intervention in the future.

Asunto(s)

Genes Supresores de Tumor; Metástasis de la Neoplasia/genética; Metástasis de la Neoplasia/fisiopatología; Oncogenes; Neoplasias de la Próstata/genética; Neoplasias de la Próstata/fisiopatología; Daño del ADN; Reparación del ADN; Humanos; Masculino; Pronóstico

Buscar en Google

Imprimir

XML

PubMed Links

Colección: 01-internacional Asunto principal: Oncogenes / Neoplasias de la Próstata / Genes Supresores de Tumor / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Prostate Cancer Prostatic Dis Asunto de la revista: ENDOCRINOLOGIA / NEOPLASIAS / UROLOGIA Año: 2004 Tipo del documento: Article País de afiliación: Reino Unido

Buscar en Google

Imprimir

XML

PubMed Links