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[Biliary stenosis, hepatitis A and valsartan: multifactorial hepatotoxicity in a surgical patient]. / Estenosis biliar, hepatitis A y valsartán: hepatotoxicidad multifactorial en un paciente quirúrgico.
Gómez, Néstor A; Mejillón, Jorge L; Zapatier, Jorge A; Vargas, Paola E.
Afiliación
  • Gómez NA; Departamento de Cirugía, Facultad de Medicina, Universidad de Guayaquil, Ecuador. ngomez@gye.satnet.net
Cir Esp ; 79(3): 189-91, 2006 Mar.
Article en Es | MEDLINE | ID: mdl-16545288
We present the case of a male patient with a history of hypertension who developed acute lithiasic cholecystitis. Shortly before the patient's admission, valsartan was prescribed to control his blood pressure. Surgery was performed without complications, but during the immediate postoperative period he developed marked jaundice, light colored stools, dark urine, and malaise. A cholangiogram showed a mild stricture of the common bile duct, and laboratory analyses revealed IgM antibodies against hepatitis A virus. Moreover, the patient reported the he continued to take valsartan. The patient improved with conservative treatment without any further complaints. In patients with jaundice after biliary surgery, exhaustive studies must be carried out before reintervention is performed, including investigation of the administration of drugs with potential hepatotoxic effects.
Asunto(s)
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Colección: 01-internacional Asunto principal: Tetrazoles / Valina / Colestasis / Enfermedad Hepática Inducida por Sustancias y Drogas / Hepatitis A / Hipertensión / Antihipertensivos Límite: Humans / Male / Middle aged Idioma: Es Revista: Cir esp Año: 2006 Tipo del documento: Article País de afiliación: Ecuador
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Colección: 01-internacional Asunto principal: Tetrazoles / Valina / Colestasis / Enfermedad Hepática Inducida por Sustancias y Drogas / Hepatitis A / Hipertensión / Antihipertensivos Límite: Humans / Male / Middle aged Idioma: Es Revista: Cir esp Año: 2006 Tipo del documento: Article País de afiliación: Ecuador