ERICA predicts response to tamoxifen in elderly women with breast cancer.
Ann R Coll Surg Engl
; 73(6): 361-3, 1991 Nov.
Article
en En
| MEDLINE
| ID: mdl-1759765
ABSTRACT
Oestrogen receptor status has been determined by an immunocytochemical assay using fine-needle aspiration samples of primary breast cancers in elderly patients. In a prospective study 56 patients were treated with tamoxifen only. Satisfactory assays were achieved in 49 patients. Disease was controlled by tamoxifen in 32 of 35 (91%) patients with oestrogen receptor positive tumours, compared with only 1 (7%) of 14 who were receptor negative. Immunocytochemical assay on fine-needle aspiration samples is relatively non-invasive and simple to perform, it accurately predicts response to tamoxifen in elderly patients and can be used to select patients for tamoxifen only therapy.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Tamoxifeno
/
Neoplasias de la Mama
/
Receptores de Estrógenos
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
Idioma:
En
Revista:
Ann R Coll Surg Engl
Año:
1991
Tipo del documento:
Article