[Chondroradionecrosis in two patients with laryngeal carcinoma]. / Larenks karsinomlu iki hastada kondroradyonekroz.
Kulak Burun Bogaz Ihtis Derg
; 17(4): 242-8, 2007.
Article
en Tr
| MEDLINE
| ID: mdl-18187981
ABSTRACT
Postradiotherapy necrosis in the larynx is a rare but serious complication. It must be differentiated from tumor recurrence with radiological and histopathological studies. Herein, we presented two patients with stage II and stage IV larynx carcinoma who developed chondroradionecrosis following radiotherapy. The first patient did not accept surgical treatment and was treated with curative radiotherapy at a dose of 70 Gy. The other one received adjuvant radiotherapy at a dose of 46 Gy following total laryngectomy and bilateral functional neck dissection. The two patients were evaluated with computed tomography and magnetic resonance imaging, respectively. Pathologic examination of multiple biopsies taken from both cases showed coagulation necrosis without malignancy. The first patient had grade IV radionecrosis according to the Chandler classification and underwent total laryngectomy because of non-functional larynx. Histopathologically, there were no malignant cells, but widespread fibrosis and coagulation necrosis. The other patient was treated with conservative treatment and local debridement.
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Colección:
01-internacional
Asunto principal:
Traumatismos por Radiación
/
Neoplasias Laríngeas
/
Laringe
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
Tr
Revista:
Kulak Burun Bogaz Ihtis Derg
Asunto de la revista:
AUDIOLOGIA
/
OTORRINOLARINGOLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Turquía