Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop.
Radiat Res
; 173(2): 245-53, 2010 Feb.
Article
en En
| MEDLINE
| ID: mdl-20095857
ABSTRACT
Radiation exposures from accidents, nuclear detonations or terrorist incidents are unlikely to be homogeneous; however, current biodosimetric approaches are developed and validated primarily in whole-body irradiation models. A workshop was held at the Armed Forces Radiobiology Research Institute in May 2008 to draw attention to the need for partial-body biodosimetry, to discuss current knowledge, and to identify the gaps to be filled. A panel of international experts and the workshop attendees discussed the requirements and concepts for a path forward. This report addresses eight key areas identified by the Workshop Program Committee for future focus (1) improved cytogenetics, (2) clinical signs and symptoms, (3) cutaneous bioindicators, (4) organ-specific biomarkers, (5) biophysical markers of dose, (6) integrated diagnostic approaches, (7) confounding factors, and (8) requirements for post-event medical follow-up. For each area, the status, advantages and limitations of existing approaches and suggestions for new directions are presented.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Traumatismos por Radiación
/
Biomarcadores
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Radiat Res
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos