Craniocerebral aspergillosis: a review of advances in diagnosis and management.
J Pak Med Assoc
; 60(7): 573-9, 2010 Jul.
Article
en En
| MEDLINE
| ID: mdl-20578611
ABSTRACT
Craniocerebral aspergillosis is a rare but dangerous central nervous system infection. The infection has a spectrum of presenting features, mostly affecting immunocompromised individuals. The incidence appears to be on the rise that has been especially observed in the immunocompetent population. A high index of suspicion, a comprehensive understanding of the infectious process and advanced laboratory and radiological diagnostic techniques, allow early diagnosis. Surgery, followed by systemic antifungal medications, remains the cornerstone of management. Early administration of empirical anti-fungal agents along with immunomodulators may further improve prognosis. Immunocompetent patients tend to have better outcomes as compared to those who are immunocompromised. Patients with intradural disease carry the worst prognosis.
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Colección:
01-internacional
Asunto principal:
Encefalopatías
/
Neuroaspergilosis
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Pak Med Assoc
Año:
2010
Tipo del documento:
Article