Stable human T-cell lymphotropic virus type 1 (HTLV-1) subtype a/subgroup a endemicity in Amerindians from Northwest Argentina: a health problem to be resolved.
J Med Virol
; 82(12): 2116-22, 2010 Dec.
Article
en En
| MEDLINE
| ID: mdl-20981802
ABSTRACT
Jujuy province, in Northwest Argentina, is known to be endemic for HTLV-1 infection. Moreover, foci of HTLV-1 associated pathologies have also been described in this region. To gain an insight into the current situation of HTLV-1/2 in this endemic area, a seroprevalence and phylogenetic study was performed among a Kolla community from Abra Pampa city and surroundings. Out of 112 individuals, 11 (9.8%) were confirmed as HTLV-1 positive and no HTLV-2 infection was detected. The phylogenetic analysis of the LTR region showed that all the HTLV-1 sequences belonged to the Cosmopolitan subtype a/transcontinental subgroup A, and were closely related to reference sequences from Peru, Argentina, and the South of Brazil (P = 0.82). Considering the cultural and historical features of this community and in spite of the mandatory detection of anti-HTLV-1/2 antibodies in blood banks since 2005, it would be important to implement new public health measures focused on decreasing HTLV-1 transmission in this endemic area.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Virus Linfotrópico T Tipo 1 Humano
/
Infecciones por HTLV-I
/
Indígenas Sudamericanos
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Enfermedades Endémicas
Límite:
Adult
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Aged80
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Female
/
Humans
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Male
/
Middle aged
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
J Med Virol
Año:
2010
Tipo del documento:
Article
País de afiliación:
Argentina