Topoisomerase 1 inhibitors and cancer therapy.
Hematol Oncol Clin North Am
; 26(3): 507-25, vii, 2012 Jun.
Article
en En
| MEDLINE
| ID: mdl-22520977
ABSTRACT
Topoisomerase 1 inhibitors cure human cancer xenografts in animal models, more so than most other chemotherapy agents. However, their activity in patients with cancer is modest. Ongoing research is studying the optimal analogues that could reproduce animal data in the cancer population. This article analyzes the clinical research with topoisomerase 1 inhibitors in ovarian cancer.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Neoplasias Ováricas
/
Inhibidores de Topoisomerasa I
Límite:
Female
/
Humans
Idioma:
En
Revista:
Hematol Oncol Clin North Am
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos