Andhraxylocarpinsâ
A-E: structurally intriguing limonoids from the true mangroves Xylocarpus granatum and Xylocarpus moluccensis.
Chemistry
; 18(45): 14342-51, 2012 Nov 05.
Article
en En
| MEDLINE
| ID: mdl-23008237
ABSTRACT
Five new limonoids, including andhraxylocarpinsâ
A and B (1 and 2) which contain a 9-oxa-tricyclo[3.3.2.1(7, 10)]undecane-2-ene motif, andhraxylocarpinsâ
C and D (3 and 4), which contain a (Z)-bicyclo[5.2.1]dec-3-en-8-one substructure, and andhraxylocarpinâ
E (5), which contains a tricyclo[3.3.1.1(3, 6)]decane-9-one scaffold, were isolated from the seeds of two true mangroves, Xylocarpus granatum and Xylocarpus moluccensis, that were collected in the estuaries of Andhra Pradesh, India. The absolute configurations of these compounds were determined by extensive NMR investigations, single-crystal X-ray diffraction analysis, and by circular dichroism and optical rotatory dispersion spectroscopy, in combination with quantum-chemical calculations. The pronounced structural diversity of limonoids from these mangroves might originate from environmental factors.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Meliaceae
/
Limoninas
/
Antineoplásicos Fitogénicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Chemistry
Asunto de la revista:
QUIMICA
Año:
2012
Tipo del documento:
Article