Wnt signalling in pituitary development and tumorigenesis.
Endocr Relat Cancer
; 20(3): R101-11, 2013 Jun.
Article
en En
| MEDLINE
| ID: mdl-23689382
ABSTRACT
Wnt signalling is activated in both pituitary organogenesis and its mature function. Wnt ligands and Wnt signalling pathways are critical for the regulation of the formation of the pituitary. In the mature pituitary, Wnt signalling pathways control cell activity and may stimulate cell proliferation in both physiological and pathological processes. This review compares Wnt signalling pathways active in the developing and mature pituitary and explores how this gives us further insight into the development of pituitary adenomas.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Hipófisis
/
Neoplasias Hipofisarias
/
Proteínas Wnt
/
Vía de Señalización Wnt
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Endocr Relat Cancer
Asunto de la revista:
ENDOCRINOLOGIA
/
NEOPLASIAS
Año:
2013
Tipo del documento:
Article
País de afiliación:
Reino Unido