Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS.
Metabolism
; 63(10): 1257-64, 2014 Oct.
Article
en En
| MEDLINE
| ID: mdl-25125349
ABSTRACT
OBJECTIVE:
To determine if consumption of a reduced-carbohydrate (CHO) diet would result in preferential loss of adipose tissue under eucaloric conditions, and whether changes in adiposity were associated with changes in postprandial insulin concentration.METHODS:
In a crossover-diet intervention, 30 women with PCOS consumed a reduced-CHO diet (411940% energy from CHOproteinfat) for 8 weeks and a standard diet (551827) for 8 weeks. Body composition by DXA and fat distribution by CT were assessed at baseline and following each diet phase. Insulin AUC was obtained from a solid meal test (SMT) during each diet phase.RESULTS:
Participants lost 3.7% and 2.2% total fat following the reduced-CHO diet and STD diet, resp. (p<0.05 for difference between diets). The reduced-CHO diet induced a decrease in subcutaneous-abdominal, intra-abdominal, and thigh-intermuscular adipose tissue (-7.1%, -4.6%, and -11.5%, resp.), and the STD diet induced a decrease in total lean mass. Loss of fat mass following the reduced CHO diet arm was associated with lower insulin AUC (p<0.05) during the SMT.CONCLUSIONS:
In women with PCOS, consumption of a diet lower in CHO resulted in preferential loss of fat mass from metabolically harmful adipose depots, whereas a diet high in CHO appeared to promote repartitioning of lean mass to fat mass.Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Síndrome del Ovario Poliquístico
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Composición Corporal
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Carbohidratos de la Dieta
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Tejido Adiposo
Tipo de estudio:
Clinical_trials
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Metabolism
Año:
2014
Tipo del documento:
Article