Dahuang Fuzi Decoction ameliorates tubular epithelial apoptosis and renal damage via inhibiting TGF-ß1-JNK signaling pathway activation in vivo.

Tu, Yue; Sun, Wei; Wan, Yi-Gang; Gao, Kun; Liu, Hong; Yu, Bing-Yin; Hu, Hao; Huang, Yan-Ru

Tu, Yue; Sun, Wei; Wan, Yi-Gang; Gao, Kun; Liu, Hong; Yu, Bing-Yin; Hu, Hao; Huang, Yan-Ru.

Afiliación

Tu Y; Department of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China; Department of Graduate School, Nanjing University of Chinese Medicine, Nanjng, China.
Sun W; Department of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: 381968515@qq.com.
Wan YG; Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Gao K; Department of Molecular Signaling, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi, Japan.
Liu H; Department of Graduate School, Nanjing University of Chinese Medicine, Nanjng, China.
Yu BY; Department of Graduate School, Nanjing University of Chinese Medicine, Nanjng, China.
Hu H; Department of Graduate School, Nanjing University of Chinese Medicine, Nanjng, China.
Huang YR; Department of Graduate School, Nanjing University of Chinese Medicine, Nanjng, China.

J Ethnopharmacol ; 156: 115-24, 2014 Oct 28.

Article en En | MEDLINE | ID: mdl-25193680

Asunto(s)

Lesión Renal Aguda/tratamiento farmacológico; Apoptosis/efectos de los fármacos; Túbulos Renales/efectos de los fármacos; Sistema de Señalización de MAP Quinasas/efectos de los fármacos; Extractos Vegetales; Factor de Crecimiento Transformador beta1/efectos de los fármacos; Acetilglucosaminidasa; Alopurinol/farmacología; Animales; Modelos Animales de Enfermedad; Diterpenos; Medicamentos Herbarios Chinos; Riñón/metabolismo; Masculino; Medicina Tradicional China; Ratas; Factor de Crecimiento Transformador beta

Palabras clave

(-) asarinin (PubChem CID: 11869417); Adenine-induced renal failure; Dahuang Fuzi Decoction; Transforming growth factor-ß1; Tubular epithelial apoptosis; aloe-emodin (PubChem CID: 10207); c-JunNH2-terminal kinase; chrysophanol (PubChem CID: 10208); emodin (PubChem CID: 3220); emodin-3-methyl ether (PubChem CID: 10639); rhein (PubChem CID: 10168)

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Texto completo: 1 Colección: 01-internacional Asunto principal: Extractos Vegetales / Apoptosis / Sistema de Señalización de MAP Quinasas / Factor de Crecimiento Transformador beta1 / Lesión Renal Aguda / Túbulos Renales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2014 Tipo del documento: Article País de afiliación: China

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