Plasma beta-endorphin levels in obese and non-obese patients with polycystic ovarian disease.
Eur J Obstet Gynecol Reprod Biol
; 30(2): 151-6, 1989 Feb.
Article
en En
| MEDLINE
| ID: mdl-2522898
ABSTRACT
Several reports have shown elevated circulating beta-endorphin (beta-EP) levels in patients with polycystic ovarian disease (PCOD). However, it is not yet clear whether these high beta-EP levels are linked to the etiopathogenesis of PCOD or are secondary to the obesity. In the present study we measured beta-EP plasma concentrations in 19 PCOD patients, 10 with normal weight (Group A) and 9 with excessive weight (Group B), and in 18 normally ovulating women, 10 with normal weight (Group C) and 9 with excessive weight (Group D). beta-EP values were similar in the two groups of non-obese patients and controls. beta-EP concentrations were also similar in the two groups of obese patients and controls, and they were significantly higher (p less than 0.05) than in non-obese patients. Our data indicate that in PCOD, elevated beta-EP values are related to obesity, suggesting that they are not linked to the pathogenesis of PCOD.
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Colección:
01-internacional
Asunto principal:
Síndrome del Ovario Poliquístico
/
Betaendorfina
/
Obesidad
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Eur J Obstet Gynecol Reprod Biol
Año:
1989
Tipo del documento:
Article
País de afiliación:
Italia