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Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation.
Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Evelyne; Schmid, Inès; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S; Simon, Hans-Uwe.
Afiliación
  • Soragni A; UCLA-DOE Institute, HHMI, and Departments of Biological Chemistry and Chemistry and Biochemistry, 611 Charles E. Young Drive, University of California, Los Angeles, Los Angeles, CA 90095-1570, USA; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland; Departmen
  • Yousefi S; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland.
  • Stoeckle C; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland.
  • Soriaga AB; UCLA-DOE Institute, HHMI, and Departments of Biological Chemistry and Chemistry and Biochemistry, 611 Charles E. Young Drive, University of California, Los Angeles, Los Angeles, CA 90095-1570, USA.
  • Sawaya MR; UCLA-DOE Institute, HHMI, and Departments of Biological Chemistry and Chemistry and Biochemistry, 611 Charles E. Young Drive, University of California, Los Angeles, Los Angeles, CA 90095-1570, USA.
  • Kozlowski E; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland.
  • Schmid I; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland.
  • Radonjic-Hoesli S; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland.
  • Boutet S; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025.
  • Williams GJ; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025.
  • Messerschmidt M; National Science Foundation BioXFEL Science and Technology Center, 700 Ellicott Street, Buffalo, NY 14203, USA.
  • Seibert MM; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025.
  • Cascio D; UCLA-DOE Institute, HHMI, and Departments of Biological Chemistry and Chemistry and Biochemistry, 611 Charles E. Young Drive, University of California, Los Angeles, Los Angeles, CA 90095-1570, USA.
  • Zatsepin NA; Department of Physics, Arizona State University, Tempe, AZ 85287, USA.
  • Burghammer M; European Synchrotron Radiation Facility (ESRF), rue Jules Horowitz, 38043 Grenoble Cedex, France; Department of Analytical Chemistry, Ghent University, Krijgslaan 281, S12B, 9000 Ghent, Belgium.
  • Riekel C; European Synchrotron Radiation Facility (ESRF), rue Jules Horowitz, 38043 Grenoble Cedex, France.
  • Colletier JP; University Grenoble Alpes, IBS, 38044 Grenoble, France; CNRS, IBS, 38044 Grenoble, France; CEA, IBS, 38044 Grenoble, France.
  • Riek R; Department of Physical Chemistry, ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland. Electronic address: roland.riek@phys.chem.ethz.ch.
  • Eisenberg DS; UCLA-DOE Institute, HHMI, and Departments of Biological Chemistry and Chemistry and Biochemistry, 611 Charles E. Young Drive, University of California, Los Angeles, Los Angeles, CA 90095-1570, USA.
  • Simon HU; Institute of Pharmacology, University of Bern, Friedbuehlstrasse 49, 3010 Bern, Switzerland. Electronic address: hus@pki.unibe.ch.
Mol Cell ; 57(6): 1011-1021, 2015 Mar 19.
Article en En | MEDLINE | ID: mdl-25728769

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas de Unión al ADN / Eosinófilos Límite: Animals / Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas de Unión al ADN / Eosinófilos Límite: Animals / Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article