Dipeptidyl peptidase-4 deficiency protects against experimental diabetic nephropathy partly by blocking the advanced glycation end products-receptor axis.

Matsui, Takanori; Nakashima, Sae; Nishino, Yuri; Ojima, Ayako; Nakamura, Nobutaka; Arima, Kazunari; Fukami, Kei; Okuda, Seiya; Yamagishi, Sho-ichi

Matsui, Takanori; Nakashima, Sae; Nishino, Yuri; Ojima, Ayako; Nakamura, Nobutaka; Arima, Kazunari; Fukami, Kei; Okuda, Seiya; Yamagishi, Sho-ichi.

Afiliación

Matsui T; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
Nakashima S; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
Nishino Y; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
Ojima A; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
Nakamura N; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
Arima K; Department of Chemistry and Bioscience, Faculty of Science, Kagoshima University Graduate School of Science and Engineering, Kagoshima, Japan.
Fukami K; Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
Okuda S; Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
Yamagishi S; Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.

Lab Invest ; 95(5): 525-33, 2015 May.

Article en En | MEDLINE | ID: mdl-25730373

Asunto(s)

Nefropatías Diabéticas/metabolismo; Dipeptidil Peptidasa 4/metabolismo; Productos Finales de Glicación Avanzada/metabolismo; Albuminuria/genética; Animales; Nefropatías Diabéticas/genética; Dipeptidil Peptidasa 4/genética; Productos Finales de Glicación Avanzada/genética; Riñón/metabolismo; Riñón/patología; Masculino; Ratones Noqueados; Estrés Oxidativo/genética; Ratas; Transducción de Señal/genética

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Texto completo: 1 Colección: 01-internacional Asunto principal: Productos Finales de Glicación Avanzada / Dipeptidil Peptidasa 4 / Nefropatías Diabéticas Límite: Animals Idioma: En Revista: Lab Invest Año: 2015 Tipo del documento: Article País de afiliación: Japón

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