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Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy.
Rodenko, Boris; Wanner, Martin J; Alkhaldi, Abdulsalam A M; Ebiloma, Godwin U; Barnes, Rebecca L; Kaiser, Marcel; Brun, Reto; McCulloch, Richard; Koomen, Gerrit-Jan; de Koning, Harry P.
Afiliación
  • Rodenko B; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.
  • Wanner MJ; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands.
  • Alkhaldi AA; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Department of Biology, College of Science, Aljouf University, Skaka, Kingdom of Saudi Arabia.
  • Ebiloma GU; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Barnes RL; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Kaiser M; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.
  • Brun R; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.
  • McCulloch R; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom.
  • Koomen GJ; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands.
  • de Koning HP; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.uk.
Antimicrob Agents Chemother ; 59(11): 6708-16, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26282430
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Texto completo: 1 Colección: 01-internacional Asunto principal: Purinas / Tripanocidas / Tripanosomiasis Africana / ADN Protozoario Límite: Animals Idioma: En Revista: Antimicrob Agents Chemother Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Purinas / Tripanocidas / Tripanosomiasis Africana / ADN Protozoario Límite: Animals Idioma: En Revista: Antimicrob Agents Chemother Año: 2015 Tipo del documento: Article