Multicenter observational study comparing sedation/analgesia protocols for laser photocoagulation treatment of retinopathy of prematurity.
J Perinatol
; 35(11): 965-9, 2015 Nov.
Article
en En
| MEDLINE
| ID: mdl-26355942
ABSTRACT
OBJECTIVE:
The aim of this study was to identify the best sedation/analgesia protocol for laser photocoagulation (PC) of retinopathy of prematurity (ROP). STUDYDESIGN:
This multicenter observational study included five hospitals, each using a specific sedation/analgesia protocol local anesthesia with oxybuprocaine hydrochloride (Group L); intravenous pentazocine (Group P); intravenous fentanyl (Group F); air, oxygen and sevoflurane (AOS) inhalation (Group I). The groups were compared for pain responses, vital signs and adverse events.RESULTS:
Heart rates and systemic blood pressures were elevated by PC in Groups L and P and Groups L, P and F, respectively. Moreover, poor analgesic efficacy was recognized in Groups L, P and F. In contrast, Group I experienced hypothermia, enteral feeding intolerance and apnea more frequently.CONCLUSION:
From the viewpoint of sedation/pain relief, AOS anesthesia should be the best protocol. However, considering all the various factors together, the most reasonable one can be varied based on the patient's condition and hospital.
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Dimensión del Dolor
/
Retinopatía de la Prematuridad
/
Recien Nacido Prematuro
/
Sedación Consciente
/
Fotocoagulación
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón