Absence of DAB2IP promotes cancer stem cell like signatures and indicates poor survival outcome in colorectal cancer.

Min, Jiang; Liu, Liang; Li, Xiaolan; Jiang, Jianwu; Wang, Jingtao; Zhang, Bo; Cao, Dengyi; Yu, Dongdong; Tao, Deding; Hu, Junbo; Gong, Jianping; Xie, Daxing

Min, Jiang; Liu, Liang; Li, Xiaolan; Jiang, Jianwu; Wang, Jingtao; Zhang, Bo; Cao, Dengyi; Yu, Dongdong; Tao, Deding; Hu, Junbo; Gong, Jianping; Xie, Daxing.

Afiliación

Min J; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Liu L; Gastrointestinal Surgery Department, The First Affiliated Hospital of ChongQing Medical University, Chongqing 400016, P.R. of China.
Li X; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Jiang J; Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Wang J; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Zhang B; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Cao D; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Yu D; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Tao D; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Hu J; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Gong J; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.
Xie D; Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. of China.

Sci Rep ; 5: 16578, 2015 Nov 13.

Article en En | MEDLINE | ID: mdl-26564738

Asunto(s)

Neoplasias Colorrectales/genética; Transición Epitelial-Mesenquimal/genética; Células Madre Neoplásicas/metabolismo; Proteínas Activadoras de ras GTPasa/genética; Animales; Apoptosis/efectos de los fármacos; Apoptosis/genética; Western Blotting; Línea Celular Tumoral; Neoplasias Colorrectales/tratamiento farmacológico; Neoplasias Colorrectales/metabolismo; Transición Epitelial-Mesenquimal/efectos de los fármacos; Femenino; Fluorouracilo/farmacología; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Células HCT116; Células HT29; Humanos; Estimación de Kaplan-Meier; Masculino; Ratones Desnudos; Persona de Mediana Edad; FN-kappa B/metabolismo; Células Madre Neoplásicas/efectos de los fármacos; Compuestos Organoplatinos/farmacología; Oxaliplatino; Pronóstico; Interferencia de ARN; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Ensayos Antitumor por Modelo de Xenoinjerto/métodos; Proteínas Activadoras de ras GTPasa/metabolismo

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Texto completo: 1 Colección: 01-internacional Asunto principal: Células Madre Neoplásicas / Neoplasias Colorrectales / Proteínas Activadoras de ras GTPasa / Transición Epitelial-Mesenquimal Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article

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