The progress of angiogenic factors in the development of leukemias.
Intractable Rare Dis Res
; 5(1): 6-16, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26989643
ABSTRACT
Angiogenic factors have been demonstrated to play important roles in modulating angiogenesis of solid tumors. Recently, accumulating studies extensively indicated that some angiogenic factors widely exist in malignant cells of hematologic malignancy, which regulated the expression of a number of genes that were involved in abnormal proliferation, differentiation and apoptosis of these cells. With deep research of angiogenic factors, its expression, function and regulatory mechanism were gradually elucidated, and some of them were related to the development and prognosis of leukemia, or provide more possible strategies for treatment of patients with leukemia. Herein, we summarize the progress in study of some important angiogenic factors and hematological malignancies.
Texto completo:
1
Colección:
01-internacional
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Intractable Rare Dis Res
Año:
2016
Tipo del documento:
Article
País de afiliación:
China