Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.

Nailor, Audrey; Walker, David A; Jacques, Thomas S; Warren, Kathy E; Brem, Henry; Kearns, Pamela R; Greenwood, John; Penny, Jeffrey I; Pilkington, Geoffrey J; Carcaboso, Angel M; Fleischhack, Gudrun; Macarthur, Donald; Slavc, Irene; Meijer, Lisethe; Gill, Steven; Lowis, Stephen; van Vuurden, Dannis G; Pearl, Monica S; Clifford, Steven C; Morrissy, Sorana; Ivanov, Delyan P; Beccaria, Kévin; Gilbertson, Richard J; Straathof, Karin; Green, Jordan J; Smith, Stuart; Rahman, Ruman; Kilday, John-Paul

Nailor, Audrey; Walker, David A; Jacques, Thomas S; Warren, Kathy E; Brem, Henry; Kearns, Pamela R; Greenwood, John; Penny, Jeffrey I; Pilkington, Geoffrey J; Carcaboso, Angel M; Fleischhack, Gudrun; Macarthur, Donald; Slavc, Irene; Meijer, Lisethe; Gill, Steven; Lowis, Stephen; van Vuurden, Dannis G; Pearl, Monica S; Clifford, Steven C; Morrissy, Sorana; Ivanov, Delyan P; Beccaria, Kévin; Gilbertson, Richard J; Straathof, Karin; Green, Jordan J; Smith, Stuart; Rahman, Ruman; Kilday, John-Paul.

Afiliación

Nailor A; Cancer Intelligence, 154 Cheltenham Road, Bristol, UK BS6 5RL.
Walker DA; Children's Brain Tumour Research Centre, University of Nottingham, Room EE 1833a Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK NG7 2UH.
Jacques TS; UCL Institute of Child Health, 30 Guilford St, London, UK WC1N 1EH.
Warren KE; National Cancer Institute, Building 10 - Hatfield CRC, Bethesda, MD 20892-1104.
Brem H; Johns Hopkins University, 600 N Wolfe St, Baltimore, Maryland, USA, 21287.
Kearns PR; Cancer Research UK Clinical Trials Unit, University of Birmingham, Edgbaston, Birmingham, UK B15 2TT.
Greenwood J; University College London, 11-43 Bath Street, London, UK EC1V 9EL.
Penny JI; University of Manchester, Stopford Building, Oxford Road, Manchester, UK M13 9PT.
Pilkington GJ; University of Portsmouth, Winston Churchill Ave, Portsmouth, UK, PO1 2UP.
Carcaboso AM; Institut de Recerca Pediatrica, Hospital Sant Joan de Déu, Barcelona, Spain.
Fleischhack G; Essen University Hospital, Paediatrics III, Hufelandstraße 55, Essen, Germany 45147.
Macarthur D; University Hospital Nottingham, Derby Road, Nottingham, UK NG7 2UH.
Slavc I; Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.
Meijer L; University Medical Centre Groningen, 1 Hanzeplein, Groningen, The Netherlands, 9713 GZ; University Hospital Nottingham, Derby Road, Nottingham, UK NG7 2UH.
Gill S; Bristol Royal Hospital for Children, Upper Maudlin St, Bristol, UK, BS2 8BJ.
Lowis S; Bristol Royal Hospital for Children, Upper Maudlin St, Bristol, UK, BS2 8BJ.
van Vuurden DG; VU University Medical Centre, De Boelelaan 1118, Amsterdam, Netherlands, 1081 HZ.
Pearl MS; Johns Hopkins University School of Medicine, 1800 Orleans Street, Bloomberg Building 7218, Baltimore, Maryland, USA, 21287.
Clifford SC; Newcastle University, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK, NE1 4LP.
Morrissy S; The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada, ON M5G 1X8.
Ivanov DP; University Hospital Nottingham, Derby Road, Nottingham, UK NG7 2UH.
Beccaria K; Pitié Salpetriere Hospital, Assistance Publique - Hôpitaux de Paris, 27 Rue Chaligny, Paris, France, 75012.
Gilbertson RJ; Cambridge Cancer Centre, 120 Cambridge Rd, Great Shelford, Cambridge UK, CB22 5JT.
Straathof K; Institute of Child Health, University College London, 30 Guilford Street, London, UK WC1N 1EH.
Green JJ; Institute for NanoBioTechnology, Translational Tissue Engineering Center, The Johns Hopkins University School of Medicine, 400 N. Broadway/Smith Building Room 5017, Baltimore, MD 21231.
Smith S; University Hospital Nottingham, Derby Road, Nottingham, UK NG7 2UH.
Rahman R; University Hospital Nottingham, Derby Road, Nottingham, UK NG7 2UH.
Kilday JP; Royal Manchester Children's Hospital, Oxford Rd, Manchester M13 9WL.

Ecancermedicalscience ; 10: 630, 2016.

Article en En | MEDLINE | ID: mdl-27110286

ABSTRACT

ABSTRACT

The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.

Palabras clave

CNS involvement; bloodbrain barrier; brain tumours; drug delivery; glioma; medulloblastoma; paediatrics; translational medicine

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google