Bay laurel (Laurus nobilis) as potential antiviral treatment in naturally BQCV infected honeybees.
Virus Res
; 222: 29-33, 2016 08 15.
Article
en En
| MEDLINE
| ID: mdl-27235809
ABSTRACT
Viral diseases are one of the multiple factors associated with honeybee colony losses. Apart from their innate immune system, including the RNAi machinery, honeybees can use secondary plant metabolites to reduce or fully cure pathogen infections. Here, we tested the antiviral potential of Laurus nobilis leaf ethanolic extracts on forager honeybees naturally infected with BQCV (Black queen cell virus). Total viral loads were reduced even at the lowest concentration tested (1mg/ml). Higher extract concentrations (≥5mg/ml) significantly reduced virus replication. Measuring vitellogenin gene expression as an indicator for transcript homeostasis revealed constant RNA levels before and after treatment, suggesting that its expression was not impacted by the L. nobilis treatment. In conclusion, plant secondary metabolites can reduce virus loads and virus replication in naturally infected honeybees.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Antivirales
/
Picornaviridae
/
Abejas
/
Extractos Vegetales
/
Infecciones por Picornaviridae
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Laurus
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Enfermedades de los Animales
Límite:
Animals
Idioma:
En
Revista:
Virus Res
Asunto de la revista:
VIROLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Rumanía