Polymorphisms within the COL5A1 gene and regulators of the extracellular matrix modify the risk of Achilles tendon pathology in a British case-control study.

Brown, Karryn L; Seale, Kirsten B; El Khoury, Louis Y; Posthumus, Michael; Ribbans, William J; Raleigh, Stuart M; Collins, Malcolm; September, Alison V

Brown, Karryn L; Seale, Kirsten B; El Khoury, Louis Y; Posthumus, Michael; Ribbans, William J; Raleigh, Stuart M; Collins, Malcolm; September, Alison V.

Afiliación

Brown KL; a Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences , University of Cape Town , Cape Town , South Africa.
Seale KB; a Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences , University of Cape Town , Cape Town , South Africa.
El Khoury LY; b The Centre for Physical Activity and Chronic Disease, The Institute of Health and Wellbeing , University of Northampton , Northampton , UK.
Posthumus M; c School of Biological Sciences , University of Essex , Colchester , UK.
Ribbans WJ; a Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences , University of Cape Town , Cape Town , South Africa.
Raleigh SM; b The Centre for Physical Activity and Chronic Disease, The Institute of Health and Wellbeing , University of Northampton , Northampton , UK.
Collins M; b The Centre for Physical Activity and Chronic Disease, The Institute of Health and Wellbeing , University of Northampton , Northampton , UK.
September AV; a Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences , University of Cape Town , Cape Town , South Africa.

J Sports Sci ; 35(15): 1475-1483, 2017 Aug.

Article en En | MEDLINE | ID: mdl-27541197

Asunto(s)

Tendón Calcáneo/lesiones; Tendón Calcáneo/patología; Colágeno Tipo V/genética; Matriz Extracelular/metabolismo; Polimorfismo Genético; Rotura/genética; Tendinopatía/genética; Adulto; Alelos; Estudios de Casos y Controles; Caspasa 8/genética; Femenino; Frecuencia de los Genes; Predisposición Genética a la Enfermedad; Genotipo; Humanos; Interleucina-1beta/genética; Interleucina-6/genética; Masculino; Repeticiones de Microsatélite; Persona de Mediana Edad; Tendinopatía/metabolismo; Ubiquitina-Proteína Ligasas/genética

Palabras clave

Type V collagen; caspase-8; interleukins; microRNA; polymorphism

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Texto completo: 1 Colección: 01-internacional Asunto principal: Polimorfismo Genético / Rotura / Tendón Calcáneo / Colágeno Tipo V / Tendinopatía / Matriz Extracelular Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Sports Sci Año: 2017 Tipo del documento: Article País de afiliación: Sudáfrica

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