Bone-protective Functions of Netrin 1 Protein.

Maruyama, Kenta; Kawasaki, Takahiko; Hamaguchi, Masahide; Hashimoto, Motomu; Furu, Moritoshi; Ito, Hiromu; Fujii, Takao; Takemura, Naoki; Karuppuchamy, Thangaraj; Kondo, Takeshi; Kawasaki, Takumi; Fukasaka, Masahiro; Misawa, Takuma; Saitoh, Tatsuya; Suzuki, Yutaka; Martino, Mikaël M; Kumagai, Yutaro; Akira, Shizuo

Maruyama, Kenta; Kawasaki, Takahiko; Hamaguchi, Masahide; Hashimoto, Motomu; Furu, Moritoshi; Ito, Hiromu; Fujii, Takao; Takemura, Naoki; Karuppuchamy, Thangaraj; Kondo, Takeshi; Kawasaki, Takumi; Fukasaka, Masahiro; Misawa, Takuma; Saitoh, Tatsuya; Suzuki, Yutaka; Martino, Mikaël M; Kumagai, Yutaro; Akira, Shizuo.

Afiliación

Maruyama K; From the Laboratories of Host Defense and maruyama@biken.osaka-u.ac.jp.
Kawasaki T; the Division of Brain Function, National Institute of Genetics, 1111 Yata, Mishima 411-8540, Japan.
Hamaguchi M; Experimental Immunology, World Premier Institute (WPI) Immunology Frontier Research Center (IFReC) and.
Hashimoto M; the Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Furu M; the Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Ito H; the Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Fujii T; the Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Takemura N; the Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccine, Institute for Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Karuppuchamy T; From the Laboratories of Host Defense and.
Kondo T; From the Laboratories of Host Defense and.
Kawasaki T; From the Laboratories of Host Defense and.
Fukasaka M; From the Laboratories of Host Defense and.
Misawa T; From the Laboratories of Host Defense and.
Saitoh T; From the Laboratories of Host Defense and.
Suzuki Y; the Department of Inflammation Biology, Institute for Enzyme Research, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.
Martino MM; the Departments of Functional Genomics and Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan, and.
Kumagai Y; From the Laboratories of Host Defense and.
Akira S; the European Molecular Biology Laboratory, Australian Regenerative Medicine Institute, Monash University, Victoria 3800, Australia.

J Biol Chem ; 291(46): 23854-23868, 2016 Nov 11.

Article en En | MEDLINE | ID: mdl-27681594

Asunto(s)

Artritis Reumatoide/tratamiento farmacológico; Resorción Ósea/prevención & control; Factores de Crecimiento Nervioso/farmacología; Osteoclastos/metabolismo; Membrana Sinovial/metabolismo; Proteínas Supresoras de Tumor/farmacología; Animales; Artritis Reumatoide/genética; Artritis Reumatoide/metabolismo; Artritis Reumatoide/patología; Resorción Ósea/genética; Resorción Ósea/metabolismo; Resorción Ósea/patología; Modelos Animales de Enfermedad; Femenino; Fibroblastos/metabolismo; Fibroblastos/patología; Humanos; Masculino; Ratones; Ratones Endogámicos ICR; Ratones Mutantes; Factores de Crecimiento Nervioso/biosíntesis; Factores de Crecimiento Nervioso/genética; Receptores de Netrina; Netrina-1; Neuropéptidos/genética; Neuropéptidos/metabolismo; Osteoclastos/patología; Proteína Tirosina Fosfatasa no Receptora Tipo 6/genética; Proteína Tirosina Fosfatasa no Receptora Tipo 6/metabolismo; Proteínas Proto-Oncogénicas c-vav/genética; Proteínas Proto-Oncogénicas c-vav/metabolismo; Receptores de Superficie Celular/biosíntesis; Receptores de Superficie Celular/genética; Membrana Sinovial/patología; Proteínas Supresoras de Tumor/biosíntesis; Proteínas Supresoras de Tumor/genética; Proteína de Unión al GTP rac1/genética; Proteína de Unión al GTP rac1/metabolismo

Palabras clave

arthritis; cell fusion; interleukin 17A (IL-17 or IL-17A); netrin 1; osteoblast; osteoclast; osteoporosis; rheumatoid arthritis

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Texto completo: 1 Colección: 01-internacional Asunto principal: Osteoclastos / Artritis Reumatoide / Membrana Sinovial / Resorción Ósea / Proteínas Supresoras de Tumor / Factores de Crecimiento Nervioso Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article

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