Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells.

Liu, Hung-Yi; Greene, Tanja; Lin, Tsai-Yu; Dawes, Camron S; Korc, Murray; Lin, Chien-Chi

Liu, Hung-Yi; Greene, Tanja; Lin, Tsai-Yu; Dawes, Camron S; Korc, Murray; Lin, Chien-Chi.

Afiliación

Liu HY; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Greene T; Department of Biomedical Engineering, Purdue School of Engineering & Technology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Lin TY; Department of Biomedical Engineering, Purdue School of Engineering & Technology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Dawes CS; Department of Biomedical Engineering, Purdue School of Engineering & Technology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Korc M; Department of Medicine and Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA.
Lin CC; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Biomedical Engineering, Purdue School of Engineering & Technology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA; Indiana University Melvin and Bren Simon Can

Acta Biomater ; 48: 258-269, 2017 01 15.

Article en En | MEDLINE | ID: mdl-27769941

Asunto(s)

Hidrogeles/química; Monofenol Monooxigenasa/metabolismo; Matriz Extracelular/metabolismo; Regulación de la Expresión Génica; Humanos; Metaloproteinasas de la Matriz/metabolismo; Miofibroblastos/citología; Norbornanos/química; Células Estrelladas Pancreáticas/citología; Células Estrelladas Pancreáticas/metabolismo; Péptidos/química; Polietilenglicoles/química; Polimerizacion; Proteolisis; Compuestos de Sulfhidrilo/química

Palabras clave

Hydrogels; Pancreatic cancer; Stellate cells; Tissue stiffening; Tyrosinase

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Texto completo: 1 Colección: 01-internacional Asunto principal: Monofenol Monooxigenasa / Hidrogeles Límite: Humans Idioma: En Revista: Acta Biomater Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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