Long-term effects of high-intensity interval training in heart transplant recipients: A 5-year follow-up study of a randomized controlled trial.
Clin Transplant
; 31(1)2017 01.
Article
en En
| MEDLINE
| ID: mdl-27865004
ABSTRACT
BACKGROUND:
Previous studies have demonstrated that high-intensity interval training (HIT) is superior to moderate-continuous exercise in general and in cardiovascular diseases. Recently, we also found HIT safe and efficient after heart transplantation (HTx). This study reports the 5-year long-term effects. DESIGN ANDMETHODS:
Forty-one HTx patients who had completed the previous 12-month randomized controlled trial, comparing HIT intervention with usual care, were eligible. In particular, we measured VO2peak , muscular capacity, intravascular ultrasound, and questionnaires measuring physical and mental health.RESULTS:
The baseline mean±SD values were as follows age; 49.1±16.5 years, men; 68%, time since HTx 4.1±2.2 years. Within the HIT group, initial VO2peak increased significantly from 27.7±5.7 to 31.2±5.3 mL/kg/min. However, during the next 4 years, VO2peak decreased to 26.0±6.2 mL/kg/min. The control group showed slightly decreasing VO2peak values during the entire 5-year period. The HIT group reported significantly less anxiety symptoms, but there were no long-term differences in VO2peak , muscular capacity, or cardiac allograft vasculopathy between the groups. The similar VO2peak values correspond to our findings of similar everyday activity.CONCLUSION:
Our findings suggest that intermittent periods of HIT may be necessary to maintain the initial benefits gained from the intervention. However, HIT probably reduces the burden of anxiety, which is a frequent health issue following HTx.Palabras clave
Texto completo:
1
Colección:
01-internacional
Asunto principal:
Ejercicio Físico
/
Trasplante de Corazón
/
Receptores de Trasplantes
/
Entrenamiento de Intervalos de Alta Intensidad
/
Cardiopatías
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Transplant
Asunto de la revista:
TRANSPLANTE
Año:
2017
Tipo del documento:
Article
País de afiliación:
Noruega