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Strategies to design clinical studies to identify predictive biomarkers in cancer research.
Perez-Gracia, Jose Luis; Sanmamed, Miguel F; Bosch, Ana; Patiño-Garcia, Ana; Schalper, Kurt A; Segura, Victor; Bellmunt, Joaquim; Tabernero, Josep; Sweeney, Christopher J; Choueiri, Toni K; Martín, Miguel; Fusco, Juan Pablo; Rodriguez-Ruiz, Maria Esperanza; Calvo, Alfonso; Prior, Celia; Paz-Ares, Luis; Pio, Ruben; Gonzalez-Billalabeitia, Enrique; Gonzalez Hernandez, Alvaro; Páez, David; Piulats, Jose María; Gurpide, Alfonso; Andueza, Mapi; de Velasco, Guillermo; Pazo, Roberto; Grande, Enrique; Nicolas, Pilar; Abad-Santos, Francisco; Garcia-Donas, Jesus; Castellano, Daniel; Pajares, María J; Suarez, Cristina; Colomer, Ramon; Montuenga, Luis M; Melero, Ignacio.
Afiliación
  • Perez-Gracia JL; Department of Oncology, University Clinic of Navarra, Pamplona, Spain; Health Research Institute of Navarra (IDISNA), Pamplona, Spain. Electronic address: jlgracia@unav.es.
  • Sanmamed MF; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Bosch A; Division of Oncology and Pathology Department of Clinical Sciences, Lund University, Sweden.
  • Patiño-Garcia A; Department of Pediatrics and CIMA LAB Diagnostics, University Clinic of Navarra, Pamplona, Spain; Health Research Institute of Navarra (IDISNA), Pamplona, Spain.
  • Schalper KA; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
  • Segura V; IDISNA and Bioinformatics Unit, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Navarra, Spain.
  • Bellmunt J; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Tabernero J; Department of Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Sweeney CJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Choueiri TK; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Martín M; Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense, Madrid, Spain.
  • Fusco JP; Department of Oncology, University Clinic of Navarra, Pamplona, Spain.
  • Rodriguez-Ruiz ME; Department of Oncology, University Clinic of Navarra, Pamplona, Spain; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
  • Calvo A; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Department of Histology and Pathology, School of Medicine, University of Navarra, Pamplona, Navarra, Spain.
  • Prior C; Department of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
  • Paz-Ares L; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Pio R; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Program in Solid Tumors and Biomarkers, CIMA, University of Navarra, Spain.
  • Gonzalez-Billalabeitia E; Department of Hematology and Medical Oncology, Hospital Universitario Morales Meseguer, Universidad Católica San Antonio de Murcia, Murcia, Spain.
  • Gonzalez Hernandez A; Department of Biochemistry, University Clinic of Navarra, Pamplona, Spain.
  • Páez D; Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Piulats JM; Department of Medical Oncology, Institut Català d'Oncologia, Barcelona, Spain.
  • Gurpide A; Department of Oncology, University Clinic of Navarra, Pamplona, Spain; Health Research Institute of Navarra (IDISNA), Pamplona, Spain.
  • Andueza M; Department of Oncology, University Clinic of Navarra, Pamplona, Spain.
  • de Velasco G; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Pazo R; Department of Medical Oncology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
  • Grande E; Department of Medical Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
  • Nicolas P; Chair in Law and the Human Genome, University of the Basque Country, Bizkaia, Spain.
  • Abad-Santos F; Clinical Pharmacology Service, Hospital Universitario de la Princesa, Instituto Teófilo Hernando, University Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria la Princesa (IP), Madrid, Spain.
  • Garcia-Donas J; Department of Medical Oncology, HM Hospitales - Centro Integral Oncológico HM Clara Campal, Madrid, Spain.
  • Castellano D; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Pajares MJ; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Department of Histology and Pathology, School of Medicine, University of Navarra, Pamplona, Navarra, Spain; Program in Solid Tumors and Biomarkers, CIMA, University of Navarra, Spain.
  • Suarez C; Department of Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Colomer R; Department of Oncology, Hospital Universitario de la Princesa, Spain.
  • Montuenga LM; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Department of Histology and Pathology, School of Medicine, University of Navarra, Pamplona, Navarra, Spain; Program in Solid Tumors and Biomarkers, CIMA, University of Navarra, Spain.
  • Melero I; Department of Oncology, University Clinic of Navarra, Pamplona, Spain; Health Research Institute of Navarra (IDISNA), Pamplona, Spain; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Cancer Treat Rev ; 53: 79-97, 2017 Feb.
Article en En | MEDLINE | ID: mdl-28088073
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Texto completo: 1 Colección: 01-internacional Asunto principal: Biomarcadores de Tumor / Investigación Biomédica Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Treat Rev Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Biomarcadores de Tumor / Investigación Biomédica Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Treat Rev Año: 2017 Tipo del documento: Article