Enterolactone glucuronide and ß-glucuronidase in antibody directed enzyme prodrug therapy for targeted prostate cancer cell treatment.

Di, Yunyun; Ji, Shaoping; Wolf, Philipp; Krol, Ed S; Alcorn, Jane

Di, Yunyun; Ji, Shaoping; Wolf, Philipp; Krol, Ed S; Alcorn, Jane.

Afiliación

Di Y; Drug Discovery and Development Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada.
Ji S; Laboratory of Molecular Cell Biology, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Wolf P; Department of Urology, Medical Center, University of Freiburg, Freiburg, Germany.
Krol ES; Drug Discovery and Development Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada.
Alcorn J; Drug Discovery and Development Research Group, College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada. jane.alcorn@usask.ca.

AAPS PharmSciTech ; 18(6): 2336-2345, 2017 Aug.

Article en En | MEDLINE | ID: mdl-28116598

Asunto(s)

4-Butirolactona/análogos & derivados; Anticuerpos/uso terapéutico; Antígenos de Superficie/inmunología; Glucuronidasa/uso terapéutico; Glucurónidos/uso terapéutico; Glutamato Carboxipeptidasa II/inmunología; Lignanos/uso terapéutico; Profármacos/uso terapéutico; Neoplasias de la Próstata/tratamiento farmacológico; Proteínas Recombinantes de Fusión/uso terapéutico; 4-Butirolactona/uso terapéutico; Animales; Células COS; Chlorocebus aethiops; Humanos; Masculino; Neoplasias de la Próstata/patología

Palabras clave

ADEPT; enterolactone; enterolactone glucuronide; flaxseed lignans; ß-glucuronidase

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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias de la Próstata / Proteínas Recombinantes de Fusión / 4-Butirolactona / Profármacos / Lignanos / Glucurónidos / Glutamato Carboxipeptidasa II / Glucuronidasa / Anticuerpos / Antígenos de Superficie Límite: Animals / Humans / Male Idioma: En Revista: AAPS PharmSciTech Asunto de la revista: FARMACOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Canadá

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