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Intravitreous injection of AAV2-sFLT01 in patients with advanced neovascular age-related macular degeneration: a phase 1, open-label trial.
Heier, Jeffrey S; Kherani, Saleema; Desai, Shilpa; Dugel, Pravin; Kaushal, Shalesh; Cheng, Seng H; Delacono, Cheryl; Purvis, Annie; Richards, Susan; Le-Halpere, Annaig; Connelly, John; Wadsworth, Samuel C; Varona, Rafael; Buggage, Ronald; Scaria, Abraham; Campochiaro, Peter A.
Afiliación
  • Heier JS; Ophthalmic Consultants of Boston, Boston, MA, USA.
  • Kherani S; Departments of Ophthalmology and Neuroscience, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.
  • Desai S; Ophthalmic Consultants of Boston, Boston, MA, USA.
  • Dugel P; Retinal Consultants of Arizona, Phoenix, AZ, USA.
  • Kaushal S; University of Massachusetts Medical Center, Worcester, MA, USA.
  • Cheng SH; Sanofi Genzyme, Cambridge, MA, USA.
  • Delacono C; Sanofi Genzyme, Cambridge, MA, USA.
  • Purvis A; Sanofi Genzyme, Cambridge, MA, USA.
  • Richards S; Sanofi Genzyme, Cambridge, MA, USA.
  • Le-Halpere A; Sanofi Genzyme, Cambridge, MA, USA.
  • Connelly J; Sanofi Genzyme, Cambridge, MA, USA.
  • Wadsworth SC; Sanofi Genzyme, Cambridge, MA, USA.
  • Varona R; Sanofi Genzyme, Cambridge, MA, USA.
  • Buggage R; Sanofi Genzyme, Cambridge, MA, USA.
  • Scaria A; Sanofi Genzyme, Cambridge, MA, USA.
  • Campochiaro PA; Departments of Ophthalmology and Neuroscience, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA. Electronic address: pcampo@jhmi.edu.
Lancet ; 390(10089): 50-61, 2017 07 01.
Article en En | MEDLINE | ID: mdl-28526489

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Recombinantes de Fusión / Terapia Genética / Parvovirinae / Degeneración Macular Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Asunto principal: Proteínas Recombinantes de Fusión / Terapia Genética / Parvovirinae / Degeneración Macular Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos