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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Teng, Teng; Tsai, Jennifer Hc; Puyang, Xiaoling; Seiler, Michael; Peng, Shouyong; Prajapati, Sudeep; Aird, Daniel; Buonamici, Silvia; Caleb, Benjamin; Chan, Betty; Corson, Laura; Feala, Jacob; Fekkes, Peter; Gerard, Baudouin; Karr, Craig; Korpal, Manav; Liu, Xiang; T Lowe, Jason; Mizui, Yoshiharu; Palacino, James; Park, Eunice; Smith, Peter G; Subramanian, Vanitha; Wu, Zhenhua Jeremy; Zou, Jian; Yu, Lihua; Chicas, Agustin; Warmuth, Markus; Larsen, Nicholas; Zhu, Ping.
Afiliación
  • Teng T; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Tsai JH; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Puyang X; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Seiler M; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Peng S; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Prajapati S; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Aird D; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Buonamici S; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Caleb B; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Chan B; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Corson L; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Feala J; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Fekkes P; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Gerard B; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Karr C; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Korpal M; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Liu X; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • T Lowe J; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Mizui Y; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Palacino J; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Park E; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Smith PG; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Subramanian V; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Wu ZJ; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Zou J; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Yu L; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Chicas A; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Warmuth M; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Larsen N; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
  • Zhu P; H3 Biomedicine Inc., 300 Technology Sq, 5th Floor, Cambridge, Massachusetts 02139, USA.
Nat Commun ; 8: 15522, 2017 05 25.
Article en En | MEDLINE | ID: mdl-28541300
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Texto completo: 1 Colección: 01-internacional Asunto principal: Fosfoproteínas / Proteínas Portadoras / Adenosina / Empalme Alternativo / Factores de Empalme de ARN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Fosfoproteínas / Proteínas Portadoras / Adenosina / Empalme Alternativo / Factores de Empalme de ARN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos