LC-MS/MS isomeric profiling of permethylated N-glycans derived from serum haptoglobin of hepatocellular carcinoma (HCC) and cirrhotic patients.

Huang, Yifan; Zhou, Shiyue; Zhu, Jianhui; Lubman, David M; Mechref, Yehia

Huang, Yifan; Zhou, Shiyue; Zhu, Jianhui; Lubman, David M; Mechref, Yehia.

Afiliación

Huang Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Zhou S; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Zhu J; Department of Surgery, The University of Michigan, Ann Arbor, MI, USA.
Lubman DM; Department of Surgery, The University of Michigan, Ann Arbor, MI, USA.
Mechref Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.

Electrophoresis ; 38(17): 2160-2167, 2017 09.

Article en En | MEDLINE | ID: mdl-28543513

Asunto(s)

Carcinoma Hepatocelular/metabolismo; Cromatografía Liquida/métodos; Haptoglobinas/análisis; Cirrosis Hepática/metabolismo; Neoplasias Hepáticas/metabolismo; Polisacáridos/análisis; Biomarcadores de Tumor/sangre; Carcinoma Hepatocelular/sangre; Glicosilación; Haptoglobinas/química; Humanos; Isomerismo; Cirrosis Hepática/sangre; Neoplasias Hepáticas/sangre; Polisacáridos/química; Análisis de Componente Principal; Espectrometría de Masas en Tándem/métodos

Palabras clave

Cirrhosis; Glycans biomarker discovery; Hepatocellular carcinoma; Isomeric separation; LC-MS/MS; Permethylated glycans

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Texto completo: 1 Colección: 01-internacional Asunto principal: Polisacáridos / Haptoglobinas / Cromatografía Liquida / Carcinoma Hepatocelular / Cirrosis Hepática / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Electrophoresis Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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