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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Lacampagne, Alain; Liu, Xiaoping; Reiken, Steven; Bussiere, Renaud; Meli, Albano C; Lauritzen, Inger; Teich, Andrew F; Zalk, Ran; Saint, Nathalie; Arancio, Ottavio; Bauer, Charlotte; Duprat, Fabrice; Briggs, Clark A; Chakroborty, Shreaya; Stutzmann, Grace E; Shelanski, Michael L; Checler, Frederic; Chami, Mounia; Marks, Andrew R.
Afiliación
  • Lacampagne A; INSERM U1046, CNRS UMR9214/LIA1185, Université de Montpellier, CHRU Montpellier, Montpellier, France.
  • Liu X; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Reiken S; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Bussiere R; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France.
  • Meli AC; INSERM U1046, CNRS UMR9214/LIA1185, Université de Montpellier, CHRU Montpellier, Montpellier, France.
  • Lauritzen I; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France.
  • Teich AF; Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Zalk R; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Saint N; INSERM U1046, CNRS UMR9214/LIA1185, Université de Montpellier, CHRU Montpellier, Montpellier, France.
  • Arancio O; Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Bauer C; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France.
  • Duprat F; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France.
  • Briggs CA; Department of Neuroscience, Rosalind Franklin University/Chicago Medical School, North Chicago, IL, 60064, USA.
  • Chakroborty S; Department of Neuroscience, Rosalind Franklin University/Chicago Medical School, North Chicago, IL, 60064, USA.
  • Stutzmann GE; Department of Neuroscience, Rosalind Franklin University/Chicago Medical School, North Chicago, IL, 60064, USA.
  • Shelanski ML; Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
  • Checler F; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France.
  • Chami M; Université Côte d'Azur, INSERM, CNRS, IPMC, Laboratory of Excellence DistALZ, 06560, Sophia-Antipolis, Valbonne, France. mchami@ipmc.cnrs.fr.
  • Marks AR; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA. arm42@columbia.edu.
Acta Neuropathol ; 134(5): 749-767, 2017 11.
Article en En | MEDLINE | ID: mdl-28631094
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Texto completo: 1 Colección: 01-internacional Asunto principal: Procesamiento Proteico-Postraduccional / Calcio / Trastornos del Conocimiento / Canal Liberador de Calcio Receptor de Rianodina / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Año: 2017 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Procesamiento Proteico-Postraduccional / Calcio / Trastornos del Conocimiento / Canal Liberador de Calcio Receptor de Rianodina / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Año: 2017 Tipo del documento: Article País de afiliación: Francia