Redox biology of Leishmania and macrophage targeted nanoparticles for therapy.

Sarwar, Hafiz Shoaib; Akhtar, Sohail; Sohail, Muhammad Farhan; Naveed, Zaeema; Rafay, Muhammad; Nadhman, Akhtar; Yasinzai, Masoom; Shahnaz, Gul

Sarwar, Hafiz Shoaib; Akhtar, Sohail; Sohail, Muhammad Farhan; Naveed, Zaeema; Rafay, Muhammad; Nadhman, Akhtar; Yasinzai, Masoom; Shahnaz, Gul.

Afiliación

Sarwar HS; Department of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Akhtar S; Department of Entomology, University College of Agriculture & Environmental Sciences, The Islamia University, Bahawalpur, Pakistan.
Sohail MF; Department of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Naveed Z; Harvard-MIT Division of Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA 0213, USA.
Rafay M; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore 54000, Pakistan.
Nadhman A; Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Yasinzai M; Department of Forestry, Range & Wild Life Management, University College of Agriculture & Environmental Sciences, The Islamia University, Bahawalpur, Pakistan.
Shahnaz G; Centre for Interdisciplinary Research in Basic Sciences, International Islamic University, Islamabad, Pakistan.

Nanomedicine (Lond) ; 12(14): 1713-1725, 2017 Jul.

Article en En | MEDLINE | ID: mdl-28635366

Asunto(s)

Portadores de Fármacos/metabolismo; Sistemas de Liberación de Medicamentos/métodos; Leishmania/efectos de los fármacos; Leishmaniasis/tratamiento farmacológico; Macrófagos/parasitología; Nanopartículas/metabolismo; Tripanocidas/administración & dosificación; Animales; Humanos; Lectinas Tipo C/metabolismo; Leishmania/fisiología; Leishmaniasis/metabolismo; Macrófagos/metabolismo; Receptor de Manosa; Lectinas de Unión a Manosa/metabolismo; Oxidación-Reducción/efectos de los fármacos; Receptores de Superficie Celular/metabolismo; Receptores Depuradores/metabolismo; Tripanocidas/farmacología

Palabras clave

intracellular delivery; leishmaniasis; macrophage targeting; mannose; nanoparticles; oxidative burst; phagolysosomal vesicles; redox biology; scavenger receptors; trypanothione reductase

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Texto completo: 1 Colección: 01-internacional Asunto principal: Tripanocidas / Portadores de Fármacos / Leishmaniasis / Sistemas de Liberación de Medicamentos / Nanopartículas / Leishmania / Macrófagos Límite: Animals / Humans Idioma: En Revista: Nanomedicine (Lond) Año: 2017 Tipo del documento: Article País de afiliación: Pakistán

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