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AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis.
Tao, Xiaoan; Lu, Yang; Qiu, Songbo; Wang, Yi; Qin, Jun; Fan, Zhen.
Afiliación
  • Tao X; Department of Oral Medicine, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong 510055, China; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Lu Y; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Qiu S; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wang Y; Center for Molecular Discovery, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Qin J; Center for Molecular Discovery, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Fan Z; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: zfan@mdanderson.org.
Cancer Lett ; 408: 33-42, 2017 11 01.
Article en En | MEDLINE | ID: mdl-28823958
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Texto completo: 1 Colección: 01-internacional Asunto principal: Especies Reactivas de Oxígeno / Apoptosis / Resistencia a Antineoplásicos / Sistema de Transporte de Aminoácidos ASC / Subunidades gamma de Complejo de Proteína Adaptadora / Receptores ErbB / Cetuximab / Neoplasias de Cabeza y Cuello Límite: Humans Idioma: En Revista: Cancer Lett Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Asunto principal: Especies Reactivas de Oxígeno / Apoptosis / Resistencia a Antineoplásicos / Sistema de Transporte de Aminoácidos ASC / Subunidades gamma de Complejo de Proteína Adaptadora / Receptores ErbB / Cetuximab / Neoplasias de Cabeza y Cuello Límite: Humans Idioma: En Revista: Cancer Lett Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos