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Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.
Steinberg, Julia; Ritchie, Graham R S; Roumeliotis, Theodoros I; Jayasuriya, Raveen L; Clark, Matthew J; Brooks, Roger A; Binch, Abbie L A; Shah, Karan M; Coyle, Rachael; Pardo, Mercedes; Le Maitre, Christine L; Ramos, Yolande F M; Nelissen, Rob G H H; Meulenbelt, Ingrid; McCaskie, Andrew W; Choudhary, Jyoti S; Wilkinson, J Mark; Zeggini, Eleftheria.
Afiliación
  • Steinberg J; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Ritchie GRS; Cancer Research Division, Cancer Council NSW, Sydney, NSW, 2011, Australia.
  • Roumeliotis TI; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Jayasuriya RL; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Clark MJ; Usher Institute of Population Health Sciences & Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK.
  • Brooks RA; MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.
  • Binch ALA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Shah KM; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Coyle R; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Pardo M; Division of Trauma & Orthopaedic Surgery, University of Cambridge, Box 180, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
  • Le Maitre CL; Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, S1 1WB, UK.
  • Ramos YFM; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Nelissen RGHH; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • Meulenbelt I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
  • McCaskie AW; Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, S1 1WB, UK.
  • Choudhary JS; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.
  • Wilkinson JM; Department of Orthopedics, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.
  • Zeggini E; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.
Sci Rep ; 7(1): 8935, 2017 08 21.
Article en En | MEDLINE | ID: mdl-28827734
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Texto completo: 1 Colección: 01-internacional Asunto principal: Osteoartritis de la Cadera / Metilación de ADN / Condrocitos / Osteoartritis de la Rodilla / Colágeno Tipo I / Lectinas Tipo C / Acuaporina 1 Tipo de estudio: Observational_studies Límite: Humans / Male Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Osteoartritis de la Cadera / Metilación de ADN / Condrocitos / Osteoartritis de la Rodilla / Colágeno Tipo I / Lectinas Tipo C / Acuaporina 1 Tipo de estudio: Observational_studies Límite: Humans / Male Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido