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BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.
Weber-Lassalle, Nana; Hauke, Jan; Ramser, Juliane; Richters, Lisa; Groß, Eva; Blümcke, Britta; Gehrig, Andrea; Kahlert, Anne-Karin; Müller, Clemens R; Hackmann, Karl; Honisch, Ellen; Weber-Lassalle, Konstantin; Niederacher, Dieter; Borde, Julika; Thiele, Holger; Ernst, Corinna; Altmüller, Janine; Neidhardt, Guido; Nürnberg, Peter; Klaschik, Kristina; Schroeder, Christopher; Platzer, Konrad; Volk, Alexander E; Wang-Gohrke, Shan; Just, Walter; Auber, Bernd; Kubisch, Christian; Schmidt, Gunnar; Horvath, Judit; Wappenschmidt, Barbara; Engel, Christoph; Arnold, Norbert; Dworniczak, Bernd; Rhiem, Kerstin; Meindl, Alfons; Schmutzler, Rita K; Hahnen, Eric.
Afiliación
  • Weber-Lassalle N; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Hauke J; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Ramser J; Department of Gynaecology and Obstetrics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.
  • Richters L; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Groß E; Department of Gynaecology and Obstetrics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.
  • Blümcke B; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Gehrig A; Department of Human Genetics, University Würzburg, Biozentrum, Würzburg, Germany.
  • Kahlert AK; Institute for Clinical Genetics, Technische Universität Dresden, Dresden, Germany.
  • Müller CR; Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Hackmann K; Department of Human Genetics, University Würzburg, Biozentrum, Würzburg, Germany.
  • Honisch E; Institute for Clinical Genetics, Technische Universität Dresden, Dresden, Germany.
  • Weber-Lassalle K; Department of Obstetrics and Gynecology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Niederacher D; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Borde J; Department of Obstetrics and Gynecology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
  • Thiele H; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Ernst C; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
  • Altmüller J; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Neidhardt G; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
  • Nürnberg P; Institute of Human Genetics, University of Cologne, Cologne, Germany.
  • Klaschik K; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Schroeder C; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
  • Platzer K; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Cologne, Germany.
  • Volk AE; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Wang-Gohrke S; Institute of Medical Genetics and Applied Genomics, University Hospital Tuebingen, Tuebingen, Germany.
  • Just W; Institute of Human Genetics, University of Leipzig Hospitals and Clinics, Leipzig, Germany.
  • Auber B; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kubisch C; Department of Obstetrics and Gynecology, Medical Faculty, University of Ulm, Ulm, Germany.
  • Schmidt G; Institute of Human Genetics, University of Ulm, Ulm, Germany.
  • Horvath J; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
  • Wappenschmidt B; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Engel C; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
  • Arnold N; Department of Gynecology and Obstetrics, University Clinics Muenster, Muenster, Germany.
  • Dworniczak B; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Straße 34, 50931, Cologne, Germany.
  • Rhiem K; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
  • Meindl A; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
  • Schmutzler RK; Institute of Clinical Molecular Biology, Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Hahnen E; Department of Gynecology and Obstetrics, University Clinics Muenster, Muenster, Germany.
Breast Cancer Res ; 20(1): 7, 2018 01 24.
Article en En | MEDLINE | ID: mdl-29368626
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Ováricas / Neoplasias de la Mama / Predisposición Genética a la Enfermedad / ARN Helicasas / Proteínas del Grupo de Complementación de la Anemia de Fanconi Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Asunto principal: Neoplasias Ováricas / Neoplasias de la Mama / Predisposición Genética a la Enfermedad / ARN Helicasas / Proteínas del Grupo de Complementación de la Anemia de Fanconi Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Alemania